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Filtered Search Results
Medchemexpress LLC Olopatadine hydrochloride | 140462-76-6 | 99.8% | 50 MG
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Olopatadine hydrochloride (ALO4943A) is a histamine blocker used to treat allergic conjunctivitis and other allergic disorders. It significantly inhibits ear swelling and the production of several interleukins. It is rapidly absorbed, with renal clearance, and has shown effectiveness in treating allergic rhinitis and chronic urticaria in clinical trials.
- Used to treat allergic conjunctivitis
- Second-generation histamine H1 receptor antagonist
- Significantly inhibits ear swelling
- Increases production of IL-4, IL-1beta, IL-6, GM-CSF, and NGF
- Highly and rapidly absorbed in healthy human volunteers
- Renal clearance drug
- Useful for treating allergic rhinitis and chronic urticaria
- Inhibits histamine release from human conjunctival mast cells
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Medchemexpress LLC Pilsicainide hydrochloride | 88069-49-2 | 99.9% | 308.85 | C17H25ClN2O | 5 MG
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Pilsicainide hydrochloride is an orally active sodium channel blocker used in research on cardiac electrophysiology. It functions as a potent class Ic antiarrhythmic agent and is provided as a solid suitable for laboratory studies.
- Orally active sodium channel blocker.
- Potent class Ic antiarrhythmic agent.
- High purity (99.94%).
- White to off-white solid appearance.
- Available in small-mass packages for analytical and pharmacological work.
- Stable when stored under recommended conditions.
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Medchemexpress LLC Bomedemstat hydrochloride | 99.9% | 556.07 g/mol | C28H35ClFN7O2 | 5 MG
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Bomedemstat hydrochloride is the hydrochloride salt of bomedemstat, an orally active, irreversible lysine-specific demethylase 1 (LSD1) inhibitor used in preclinical research to modulate histone methylation and evaluate antineoplastic activity. Supplied as a high-purity solid for research use.
- Irreversible LSD1 inhibitor.
- Hydrochloride salt for improved solubility.
- High purity (≈99.9%).
- Modulates H3K4 and H3K9 methylation.
- Suitable for in vitro and preclinical studies.
- Available as solid and as a 10 mM DMSO solution.
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Medchemexpress LLC 3-BENZYL-6-BROMO-1H- 500 mg
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3-BENZYL-6-BROMO-1H- 500MG
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Medchemexpress LLC AGAROSE WITH TAE POW 100P
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AGAROSE WITH TAE POW 100P
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Cayman Chemical 6piperazin1ylIsoquinoline hy
A synthetic intermediate useful for pharmaceutical synthesis.
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eMolecules 247129-88-0 | Diphenylvinylsulfonium triflate | Combi-Blocks, Inc. | MFCD22123284 | 362.380 | C15H13F3O3S2 | 95.000 | [O-]S(=O)(=O)C(F)(F)F.C=C[S+](c1ccccc1)c1ccccc1 | 25g | 686214806
Diphenylvinylsulfonium triflate | Combi-Blocks, Inc. | 247129-88-0 | MFCD22123284 | 362.380 | C15H13F3O3S2 | 95.000 | [O-]S(=O)(=O)C(F)(F)F.C=C[S+](c1ccccc1)c1ccccc1 | 25g | 686214806
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Medchemexpress LLC JNJ-47117096 hydroch | 1610536-69-0 | 50MG
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JNJ-47117096 hydrochloride is potent and selective MELK inhibitor with an IC50 of 23 nM also effectively inhibits Flt3 with an IC50 of 18 nM
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Ambeed FmocDTrp Boc OH
Fmoc-D-Trp(Boc)-OH, 163619-04-3, 95%
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Medchemexpress LLC Lesogaberan (hydrochloride) | 2925644-17-1 | 98.0% | 177.54 | 5 MG
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Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABAB receptor agonist, with an EC50 of 8.6 nM for human recombinant GABAB receptors. It demonstrates high affinity for rat GABAB receptors (Ki: 5.1 nM) and inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action. This compound has been shown to enhance human islet cell proliferation in vitro and protect human islet β-cells from apoptosis in islet grafts in mice. Lesogaberan hydrochloride exhibits high oral availability (88% in dogs, 100% in rats) and relatively low systemic clearance in rats, making it suitable for research applications.
- Potent and selective GABAB receptor agonist
- Inhibits transient lower esophageal sphincter relaxation
- Enhances human islet cell proliferation in vitro
- Protects human islet β-cells from apoptosis in islet grafts in mice
- High oral availability and low systemic clearance
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Medchemexpress LLC Propafenone hydrochloride | 34183-22-7 | 98.5% | 377.90 | 500 MG
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Propafenone hydrochloride is an anti-arrhythmic medication used to treat illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias. It functions by slowing the influx of sodium ions into cardiac muscle cells, which decreases cell excitability. This medication is more selective for cells with a high rate, but also blocks normal cells more than class Ia or Ib antiarrhythmics. It possesses beta-adrenergic blocker activity.
- Treats atrial and ventricular arrhythmias
- Slows influx of sodium ions into cardiac muscle cells
- Decreases cardiac cell excitability
- Exhibits beta-adrenergic blocker activity
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Medchemexpress LLC 2-BROMO-3-METHOXYCYC 100 mg
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2-BROMO-3-METHOXYCYC 100MG
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Medchemexpress LLC Acedoben | 556-08-1 | 99.9% | 25 G
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Acedoben is a biochemical agent that can form a fast self-assembled coordination complex with iron ions. The Fe-Ace coordination complex can serve as a carrier of tumor antigens and enhance antigen-specific anti-tumor immunity. This product is for research use only.
- Forms coordination complex with iron ions
- Enhances antigen-specific anti-tumor immunity
- Suitable for laboratory research applications
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Medchemexpress LLC Tropolone | 533-75-5 | MFCD00004158 | 100 G
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Tropolone is a seven-membered non-benzenoid aromatic compound and a precursor of many Azulene derivatives. It is a potent mushroom tyrosinase inhibitor with an IC50 value of 0.4 μM. Tropolone exhibits broad anti-viral and anti-fungal activity and shows synergistic effects when co-treated with nucleos(t)ide analog drugs. It is also a promising candidate for research in osteosarcoma.
- Potent mushroom tyrosinase inhibitor with an IC50 of 0.4 μM
- Exhibits broad anti-viral and anti-fungal activity
- Precursor to Azulene derivatives
- Promising candidate for osteosarcoma research
- Solid appearance, off-white to light brown color
- Purity of 99.77%
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Medchemexpress LLC Undecane | 1120-21-4 | 25 G
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Undecane is a potent cAMP agonist with anti-allergic and anti-inflammatory activities. It inhibits degranulation and the secretion of histamine and TNF-α. It reverses increased levels of p38 phosphorylation, NF-κB transcriptional activity, and target cytokine/chemokine genes. Undecane can be used for the study of skin inflammatory disorders, such as atopic dermatitis.
- Potent cAMP agonist
- Exhibits anti-allergic and anti-inflammatory activities
- Inhibits degranulation and secretion of histamine and TNF-α
- Reverses p38 phosphorylation and NF-κB transcriptional activity
- Reduces mRNA expression of inflammatory cytokines
- Suitable for studying skin inflammatory disorders
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