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Filtered Search Results
Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000568357 E-7386-1MG
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eMolecules 123696-02-6 | 3-Chloro-5-methoxypyridazine | AA Blocks LLC | MFCD08236839 | 144.560 | C5H5ClN2O | 0.000 | COc1cnnc(Cl)c1 | 10g | 410146322
3-Chloro-5-methoxypyridazine | AA Blocks LLC | 123696-02-6 | MFCD08236839 | 144.560 | C5H5ClN2O | 0.000 | COc1cnnc(Cl)c1 | 10g | 410146322
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Medchemexpress LLC Fluorenone | 486-25-9 | 100.0% | 180.20 | 1 KG
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9H-fluoren-9-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is a solid with a light yellow to yellow appearance.
- Formula: C13H8O
- Molecular weight: 180.20
- Purity: 99.97%
- Shipping: Room temperature in continental US
- Storage: Store at room temperature for 3 years; in solvent at -80°C for 2 years or -20°C for 1 year
- Solubility (in vitro): DMSO: 100 mg/mL (554.94 mM)
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eMolecules 94790-35-9 | N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate | AA Blocks LLC | MFCD01862891 | 280.580 | C5H12ClF6N2P | 0.000 | F[P-](F)(F)(F)(F)F.CN(C)C(Cl)=[N+](C)C | 25g | 460595467
N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate | AA Blocks LLC | 94790-35-9 | MFCD01862891 | 280.580 | C5H12ClF6N2P | 0.000 | F[P-](F)(F)(F)(F)F.CN(C)C(Cl)=[N+](C)C | 25g | 460595467
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eMolecules 16545-68-9 | Cyclopropanol | Ambeed | MFCD19707103 | 58.080 | C3H6O | 95.000 | OC1CC1 | 100g | 879143188
Cyclopropanol | Ambeed | 16545-68-9 | MFCD19707103 | 58.080 | C3H6O | 95.000 | OC1CC1 | 100g | 879143188
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eMolecules 133745-75-2 | N-Fluorobenzenesulfonimide | Chem-Impex | MFCD00144885 | 315.330 | C12H10FNO4S2 | 98.000 | FN(S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1 | 1kg | 386904252
N-Fluorobenzenesulfonimide | Chem-Impex | 133745-75-2 | MFCD00144885 | 315.330 | C12H10FNO4S2 | 98.000 | FN(S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1 | 1kg | 386904252
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eMolecules 56-81-5 | Glycerin | Oakwood Chemicals | MFCD00004722 | 92.094 | C3H8O3 | 99.000 | OCC(O)CO | 1kg | 480144972
Glycerin | Oakwood Chemicals | 56-81-5 | MFCD00004722 | 92.094 | C3H8O3 | 99.000 | OCC(O)CO | 1kg | 480144972
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eMolecules 126-33-0 | Sulfolane | Oakwood Chemicals | MFCD00005484 | 120.170 | C4H8O2S | 99.000 | O=S1(=O)CCCC1 | 1kg | 480131568
Sulfolane | Oakwood Chemicals | 126-33-0 | MFCD00005484 | 120.170 | C4H8O2S | 99.000 | O=S1(=O)CCCC1 | 1kg | 480131568
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Medchemexpress LLC Cyanoacetohydrazide | 140-87-4 | MFCD00007611 | 99.7% | 100 G
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Cyanoacetohydrazide is a pharmaceutical intermediate that can be used to synthesize acylhydrazide hydrazone derivatives with antibacterial or anti-tumor activity.
- Solid appearance
- Color ranges from light yellow to light brown
- Molecular weight of 99.09
- Molecular formula C3H5N3O
- Soluble in DMSO and H2O (100 mg/mL)
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Ambeed AMBEED
5000847082 N-METHYLHYDANTOIN 100G
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eMolecules 367-27-1 | 2,4-Difluorophenol | ChemScene | MFCD00009715 | 130.094 | C6H4F2O | 98.000 | Oc1ccc(F)cc1F | 25g | 894453416
2,4-Difluorophenol | ChemScene | 367-27-1 | MFCD00009715 | 130.094 | C6H4F2O | 98.000 | Oc1ccc(F)cc1F | 25g | 894453416
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eMolecules 65864-64-4 | (Difluoromethyl)trimethylsilane | Combi-Blocks | MFCD19381658 | 124.206 | C4H10F2Si | 97.000 | C[Si](C)(C)C(F)F | 100g | 448003412
(Difluoromethyl)trimethylsilane | Combi-Blocks | 65864-64-4 | MFCD19381658 | 124.206 | C4H10F2Si | 97.000 | C[Si](C)(C)C(F)F | 100g | 448003412
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Medchemexpress LLC Oxidopamine hydrochloride | 28094-15-7 | 99.9% | 50 MG
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Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine. It is a widely used neurotoxin that selectively destroys dopaminergic neurons. It promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion and can be used for the research of Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.
- Selectively destroys dopaminergic neurons.
- Promotes COX-2 activation.
- Leads to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion.
- Can be used for research of Parkinson's disease, attention-deficit hyperactivity disorder, and Lesch-Nyhan syndrome.
- Decreases viability of Neuro-2a and SH-SY5Y cells in a concentration-dependent manner.
- Induces apoptosis and mitochondrial membrane depolarization in PC12 cells.
- Increases caspase-3, -8, and -9 activities.
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Medchemexpress LLC PROTAC BCR-ABL1 ligand 1 | 2489876-34-6 | 99.2% | 250 MG
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PROTAC BCR-ABL1 ligand 1, also known as compound GMB-475, is a PROTAC ligand that allosterically targets the BCR-ABL1 protein. It recruits the E3 ligase Von Hippel-Lindau, leading to the ubiquitination and subsequent degradation of BCR-ABL1. It demonstrates cell proliferation inhibition with IC50 values ranging from 0.37 μM to 1.98 μM for different BCR-ABL1 cell types and induces the degradation of BCR-ABL1 and c-ABL1, inhibiting downstream signaling via the STAT5 pathway in a dose- and time-dependent manner.
- Targets the BCR-ABL1 protein allosterically
- Recruits the E3 ligase Von Hippel-Lindau
- Leads to ubiquitination and degradation of BCR-ABL1
- Induces degradation of BCR-ABL1 and c-ABL1
- Inhibits downstream signaling via the STAT5 pathway
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Ambeed AMBEED
5000846858 2-BROMO-3-CHLOROPHENOL 1G
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