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Filtered Search Results
Ambeed tertButyl 2 2 2aminoethoxy et
tert-Butyl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate, 153086-78-3, 97%
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Medchemexpress LLC ML-00253764 hydrochloride | 1706524-94-8 | 99.3% | 413.71 | 25 MG
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ML-00253764 hydrochloride is a brain-penetrant, nonpeptidic melanocortin receptor 4 (MC4R) antagonist. This compound exhibits a Kᵢ of 0.16 μM and an IC₅₀ of 0.103 μM, and is capable of crossing the blood-brain barrier. It is intended for research use only.
- Brain-penetrant compound
- Nonpeptidic melanocortin receptor 4 (MC4R) antagonist
- Kᵢ of 0.16 μM
- IC₅₀ of 0.103 μM
- Capable of crossing the blood-brain barrier
- Intended for research use only
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Medchemexpress LLC Cariprazine hydrochloride | 1083076-69-0 | 99.71% | 463.87 | 1 ML
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Cariprazine hydrochloride is a novel antipsychotic agent candidate that exhibits high affinity for D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). It is currently being investigated in various clinical trials for conditions such as Bipolar Disorder, Schizophrenia, and Major Depressive Disorder.
- High affinity for D3 (0.085 nM) and D2 (0.49 nM) receptors
- Moderate affinity for 5-HT1A receptor (2.6 nM)
- Antimanic properties
- Interferes with dopamine D2 receptor β-arrestin interactions
- Reduces ouabain-induced hyperactivity
- Available as a solution in DMSO
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Medchemexpress LLC (S)-Dolaphenine hydrochloride | 135383-60-7 | 98.5% | C11H13ClN2S | 1 ML
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(S)-Dolaphenine hydrochloride is a component used in the synthesis of Dolastatin 10, an antineoplastic agent known to inhibit tubulin polymerization. This product is intended solely for research purposes and is not sold to patients.
- Component used in the synthesis of Dolastatin 10.
- Precursor to an antineoplastic agent that inhibits tubulin polymerization.
- For research use only.
- Not for patient use.
- Available in solid form.
- Available in various solution concentrations.
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Medchemexpress LLC 4-(3-chloro-4-cyanophenyl)-2-(2-((1R,2R)-2-hydroxy-2-methylcyclopropyl)amino)pyrimidi. | 1610677-37-6 | 99.6% | 535.04 g·mol⁻1 | C28H31ClN6O3 | 1 ML
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Luvixasertib hydrochloride is a potent, selective inhibitor of the TTK/Mps1 kinase with low-nanomolar biochemical potency and demonstrated in vitro anticancer activity. Supplied as the hydrochloride salt in a ready-to-use 10 mM DMSO solution, it is intended for preclinical kinase assays and cellular studies probing mitotic checkpoint biology.
- High potency: IC50 1.7 nM for TTK in vitro.
- Hydrochloride salt suitable for formulation and storage.
- Provided as a 10 mM solution in DMSO, 1 mL ready to use.
- High purity (99.63% by supplier analysis).
- Well characterized: CAS 1610677-37-6; molecular weight 535.04 g·mol⁻1.
- Applications: preclinical kinase inhibition and cellular mitotic checkpoint studies.
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Ambeed Dicyclohexyl 2 4 6 triisopro
Dicyclohexyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine, 1070663-78-3, 97%
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Medchemexpress LLC Midaglizole hydrochloride | 79689-25-1 | 324.25 | 1 ML
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Midaglizole hydrochloride is a potent α2-adrenoceptor antagonist and a hypoglycemic agent. It increases blood pressure and reduces blood glucose levels in vivo by stimulating insulin release from pancreatic islets.
- Potent α2-adrenoceptor antagonist
- Hypoglycemic agent
- Increases blood pressure
- Reduces blood glucose levels
- Targets adrenergic receptor
- Relevant to metabolic disease, endocrinology, and cardiovascular disease
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Medchemexpress LLC Dorzolamide hydrochloride | 130693-82-2 | 99.86% | C10H17ClN2O4S3 | 100 MG
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Dorzolamide hydrochloride | 130693-82-2 | 99.86% | C10H17ClN2O4S3 | 100 MG
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Ambeed 6Chloro7Hpurine
6-Chloro-7H-purine, 87-42-3, 98%
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Medchemexpress LLC Ondansetron hydrochloride | 99614-01-4 | MFCD00764297 | 99.4% | C18H20ClN3O | 100 MG
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Ondansetron hydrochloride (GR 38032; SN 307) is a highly selective 5-HT3 receptor antagonist. It exerts its antiemetic effect by antagonizing 5-HT receptors in the peripheral and central nervous systems, inhibiting nausea and vomiting induced by chemotherapy and radiotherapy.
- Highly selective 5-HT3 receptor antagonist (IC50: 103 pM)
- Exerts antiemetic effect
- Inhibits nausea and vomiting from chemotherapy and radiotherapy
- Reduces EAAT3 response to L-glutamate (IC50: 8.57 μM)
- Exhibits anti-inflammatory effects through 5-HT3 receptor
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Medchemexpress LLC ML-00253764 hydrochloride | 1706524-94-8 | 99.29% | 413.71 | 50 MG
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ML-00253764 hydrochloride is a brain penetrant nonpeptidic melanocortin receptor 4 (MC4R) antagonist. It can cross the blood-brain barrier and is suitable for research applications.
- Antagonizes melanocortin receptor 4 (MC4R) activity
- Brain penetrant
- Suitable for in vitro and in vivo studies
- Supports research on tumor-induced weight loss
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Medchemexpress LLC Inupadenant hydrochloride | 2411004-22-1 | 99.6% | 641.11 g·mol⁻¹ | C25H27ClF2N8O4S2 | 5 MG
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Inupadenant hydrochloride is the hydrochloride salt of inupadenant (EOS-850), an orally active, highly selective adenosine A2A receptor antagonist reported to be non-brain-penetrant and to enhance humoral immune responses with anti-tumor activity in preclinical studies. Provided as a purified research compound for pharmacology and immuno-oncology investigations.
- Selective A2A receptor antagonist
- Orally active compound
- Does not cross the blood-brain barrier
- High purity (99.6%)
- Supplied in small research quantities suitable for in vivo and in vitro studies
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Medchemexpress LLC Desipramine hydrochloride | 58-28-6 | 99.8% | 500 MG
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Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT), and dopamine transporter (DAT) with Ki values of 4, 61, and 78,720 nM, respectively. It is intended for research use only.
- Inhibits norepinephrine transporter (NET), 5-HT transporter (SERT), and dopamine transporter (DAT).
- High purity of 99.76%.
- Available in various quantities and formulations (solid, solution in DMSO).
- Used in numerous publications, including studies on cell proliferation/viability, apoptosis-related proteins, and various cellular staining methods.
- Relevant in research areas such as infection, neurological diseases, and cancer.
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Medchemexpress LLC Ziprasidone Hydroch 5Mg | HY-14542A-5MG
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Ziprasidone Hydroch 5Mg
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Medchemexpress LLC Vernakalant hydrochloride | 748810-28-8 | 99.3% | C20H32ClNO4 | 100 MG
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Vernakalant hydrochloride is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker. It is intended for research use only.
- Potent blocker of Kv1.5 channels
- Appearance: White to light yellow solid
- Soluble in DMSO and water
- Store at 4°C, sealed, away from moisture. For solutions, store at -80°C for 6 months or -20°C for 1 month.
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