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Filtered Search Results
Medchemexpress LLC PR-Set7 protein, human | >95.0% | 50 UG
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Recombinant human PR-Set7 (amino acids K195-H352) is a lyophilized, tag-free methyltransferase fragment produced in E. coli for research applications. It monomethylates histone H4 at Lys20 and is suitable for biochemical activity assays and cell-based studies.
- Recombinant fragment K195-H352
- Expressed in E. coli, tag free
- Purity >95% by reducing SDS-PAGE
- Lyophilized from 50 mM Tris-HCl, 300 mM NaCl, pH 8.0
- Molecular weight approximately 18 kDa
- Activity ED50 = 26.51 ng/mL (specific activity 3.772x10^4 units/mg)
- Store dry at -20°C; aliquot and freeze at -80°C for long-term storage
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Medchemexpress LLC Interleukin-21 (canine), recombinant protein | >95.0% | 2 UG
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Recombinant canine interleukin-21 (IL-21) supplied lyophilized as a tag-free protein expressed in E. coli for research use. It supports studies of humoral and cellular immunity and includes formulation, storage, and analytical purity data (sequence H18-S146; accession Q6L7I9).
- Recombinant canine IL-21, tag-free
- Expressed in E. coli
- Sequence H18-S146; accession Q6L7I9
- Purity >95.0% by reducing SDS-PAGE
- Predicted mass ~15 kDa
- Lyophilized with stabilizing excipients
- Store at -20°C; reconstitute per datasheet (recommend ≥100 μg/mL)
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Medchemexpress LLC GR 64349 | 137593-52-3 | MFCD00153800 | 99.9% | 921.11 | 1 MG
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GR 64349 is a potent and highly selective NK2 receptor peptide agonist with an EC50 of 3.7 nM in rat colon. This compound demonstrates selectivity of over 1000-fold with respect to NK1 receptors and over 300-fold with respect to NK3 receptors.
- Potent and highly selective NK2 receptor peptide agonist.
- Exhibits high selectivity for NK2 receptors over NK1 and NK3 receptors.
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Medchemexpress LLC ELA-21 (human) | 2245073-05-4 | 99.97% | 2587.11 | 1 MG
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ELA-21 (human) is an apelin receptor agonist that completely inhibits Forskolin-induced cAMP production and stimulates β-arrestin recruitment with subnanomolar potencies. It acts as an agonist in both G-protein-dependent and -independent pathways.
- Apelin receptor agonist with a pKi of 8.52
- Inhibits Forskolin-induced cAMP production
- Stimulates β-arrestin recruitment
- Agonist in G-protein-dependent and -independent pathways
- White to off-white solid appearance
- Soluble in H₂O at 50 mg/mL
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Medchemexpress LLC Potassium tetraborate tetrahydrate | 12045-78-2 | MFCD00149924 | 99.0% | 100g
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Potassium tetraborate tetrahydrate 99 5% has antibacterial activity against Pectobacterium carotovorum Potassium tetraborate tetrahydrate 99 5% can be used as a biological material or organic compound for life science related research[1]
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Medchemexpress LLC Zika virus envelope (E) protein | >90.0% | 100 UG
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Recombinant Zika virus envelope (E) protein, full-length (438 amino acids), produced in Sf9 insect cells with a C-terminal His tag. Supplied as a 0.22 μm filtered buffered solution (20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.0) for research use only. Purity is reported as greater than 90% by reducing SDS-PAGE. Store at -80°C, aliquot to avoid repeated freeze-thaw cycles.
- Recombinant full-length envelope protein (438 a.a.).
- Expressed in Sf9 insect cells for eukaryotic processing.
- C-terminal His tag facilitates purification and detection.
- Supplied in a ready-to-use buffered formulation.
- Purity greater than 90% as determined by reducing SDS-PAGE.
- Suitable for immunoassays, antibody production, and biochemical characterization.
- Store at -80°C; avoid repeated freeze-thaw cycles.
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Medchemexpress LLC Cathepsin Z (CTSZ) protein, mouse, recombinant (HEK293, His-tag) | >95.0% | 500 UG
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Recombinant mouse Cathepsin Z (CTSZ) is a His-tagged protein fragment (A23-V306) produced in HEK293 cells and supplied as a lyophilized powder. The protein has an approximate molecular weight of 38 kDa and is provided at high purity for biochemical assays, antibody generation, and functional studies. Recommended storage is at -20°C, with aliquoting after reconstitution for long-term use.
- Recombinant mouse CTSZ fragment A23-V306 expressed in HEK293 cells.
- His-tag facilitates purification and detection.
- Lyophilized powder format for improved stability and shipping.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Approximate molecular weight 38 kDa for experimental planning.
- Available in multiple sizes for experimental flexibility.
- Store at -20°C and aliquot after reconstitution for long-term storage.
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Medchemexpress LLC CARM1-IN-3 dihydrochloride | 912970-67-3 | 98.8% | 481.46 | C24H34Cl2N4O2 | 10 MG
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CARM1-IN-3 dihydrochloride is a small-molecule inhibitor selective for co-activator associated arginine methyltransferase 1 (CARM1). Supplied as a white to off-white solid, it shows potent inhibition of CARM1 (IC50 = 0.07 μM) with minimal activity versus CARM3, and is intended for research use in biochemical and cellular assays. Store sealed and away from moisture; follow recommended cold storage for long-term stability.
- Potent and selective CARM1 inhibition (IC50 = 0.07 μM).
- High purity for reproducible experimental results (98.77%).
- White to off-white solid suitable for analytical and biological applications.
- Dihydrochloride salt form compatible with aqueous preparations.
- Recommended storage: sealed, away from moisture; in solvent -80°C (6 months), -20°C (1 month).
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Medchemexpress LLC Cycloguanil hydrochloride | 152-53-4 | 99.9% | 25 MG
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Cycloguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 10.8 μM against human DHFR. It functions by blocking the folate metabolic pathway, which affects nucleotide synthesis and interferes with DNA replication. It inhibits DHFR in Plasmodium, making it relevant for malaria research. Additionally, it exhibits anticancer activity by potently inhibiting DHFR in human cancer cells and blocking the transcriptional activity of STAT3.
- Inhibits dihydrofolate reductase (DHFR)
- Blocks the folate metabolic pathway
- Interferes with DNA replication and nucleotide synthesis
- Relevant for malaria research through Plasmodium DHFR inhibition
- Exhibits anticancer activity in human cancer cells
- Blocks transcriptional activity of STAT3
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Medchemexpress LLC N-methylparoxetine | 110429-36-2 | MFCD03788781 | 5g
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N-Methylparoxetine is a derivative of Paroxetine that induces Apoptosis NSCLC cells by activating mitogen-activated protein kinase ( MAPK) N-Methylparoxetine has antitumor activity[1]
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000291610 IL-21 RAT 100UG
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Medchemexpress LLC ssPA protein, E. coli (His) | >95.0% | 10 UG
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Recombinant ssPA (SspA) protein expressed in Escherichia coli with an N-terminal His tag. Supplied as a lyophilized sterile powder, the protein forms an equimolar complex with RNA polymerase holoenzyme and is useful for biochemical, structural, and functional studies. The product is high purity with low endotoxin and is recommended to be stored frozen and aliquoted after reconstitution.
- Expressed in E. coli with an N-terminal His tag.
- Supplied as lyophilized sterile powder for long-term stability.
- Greater than 95.0% purity by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Includes full-length sequence and recommended storage instructions.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000301469 3-BUTENYLAMINE HYDRO 5G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000301435 H-SAR-OTBU.HCL 100G
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Medchemexpress LLC N-[5-({[(3-fluorophenyl)carbamoyl]amino}methyl)-2-methylphenyl]imidazo[1,2-a]pyridine-3-carboxamide | 1644069-80-6 | MFCD31567545 | 99.0% | 417.44 | C23H20FN5O2 | 1 ML
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DDR Inhibitor is a small-molecule discoidin domain receptor (DDR) inhibitor for research applications. It potently inhibits DDR2 (IC50 3.3 nM), shows partial activity against DDR1 (53% inhibition at 1.5 nM), and inhibits collagen I-induced DDR2 phosphorylation in cells (EC50 8.7 nM). Available as concentrated DMSO solution or as solid for biochemical and cell-based studies.
- Potent DDR2 inhibition (IC50 3.3 nM).
- Partial DDR1 activity (53% inhibition at 1.5 nM).
- Cell-active inhibition of collagen I-induced DDR2 phosphorylation (EC50 8.7 nM).
- Available as 10 mM solution in DMSO or as solid quantities.
- High reported purity (>99% by HPLC) with COA available.
- Suitable for biochemical and cell-based DDR signaling studies.
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