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Filtered Search Results
Apexbio Technology LLC L-693,403 maleate 207455-21-8 10mg
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L-693 403 maleate (CAS 207455-21-8) is a small molecule exhibiting high affinity and selectivity for sigma ( ) receptors By modulating receptor-mediated signaling pathways it influences neuronal signal transduction at the molecular level Preclinical studies indicate that L-693 403 maleate possesses analgesic properties likely through its regulatory effects on neural activity Owing to these pharmacological characteristics it is utilized in exploratory research on neurological disorders supporting its value as a tool compound in the investigation of neural modulation mechanisms
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eMolecules 35952-69-3 | Ambeed | (2-Bromopropoxy)trimethylsilane | 1g | 572861989 | A1039449 | MFCD24477135 | 211.174 | C6H15BrOSi
Ambeed | 1-(2-(4-((4-Carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [11-biphenyl]-2-ylcarbamate | 5mg | 514324562 | A642503 | 864750-70-9 | MFCD28386316 | 597.760 | C35H43N5O4
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Medchemexpress LLC Flupirtine Maleate | 75507-68-5 | 100.0% | 420.39 | 100 MG
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Flupirtine Maleate is an orally active, blood-brain barrier-crossing non-opioid analgesic and neuroprotective agent. It functions as a neuronal potassium channel opener (Kv7 activator), an NMDA receptor antagonist, and a GABA receptor activator. This agent is suitable for research related to focal cerebral ischemia, pain, Alzheimer's disease, or multiple sclerosis.
- Stabilizes blood-brain barrier integrity.
- Reduces oxidative stress and brain leukocyte infiltration.
- Enhances angioneurogenesis.
- Suppresses calcium influx.
- Stabilizes neuronal resting membrane potential.
- Counteracts focal cerebral ischemia.
- Exhibits analgesic and muscle relaxant properties.
- Protects neurons from excitotoxic, ischemic, or cytokine-mediated death.
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Medchemexpress LLC BRL-44408 maleate | 681806-46-2 | 99.0% | 10 MG
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BRL-44408 maleate is a selective, blood-brain barrier-permeable α2A-adrenergic receptor antagonist with a Kᵢ value of 8.56 nM against human targets. It exhibits antidepressant and analgesic effects, and attenuates sepsis-induced acute lung injury by regulating neurotransmitter release or inhibiting signaling pathways. It can be used in studies related to acute respiratory distress syndrome, depression, and visceral pain.
- Selective α2A-adrenergic receptor antagonist
- Blood-brain barrier permeable
- Exhibits antidepressant and analgesic effects
- Attenuates sepsis-induced acute lung injury
- Regulates neurotransmitter release and inhibits signaling pathways
- Used in studies for acute respiratory distress syndrome, depression, and visceral pain
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Medchemexpress LLC Tegaserod (maleate) | 189188-57-6 | 99.9% | C20H27N5O5 | 25 MG
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Tegaserod maleate is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. It induces tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling, and decreases S6 phosphorylation, exhibiting anti-tumor activity.
- Orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist
- 5-HT2B receptor antagonist
- Induces tumor cell apoptosis
- Blunts PI3K/Akt/mTOR signaling
- Decreases S6 phosphorylation
- Exhibits anti-tumor activity
- Potential for irritable bowel syndrome (IBS) research
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eMolecules 2757470-18-9 | Medchem Express | Ensitrelvir (fumarate) | 5mg | 713704805 | HY-143216A | 647.96 | C26H21ClF3N9O6
Ambeed | 6-Bromobenzo[d]isothiazole-3-carboxylic acid | 100mg | 490496692 | A115832 | 677304-75-5 | MFCD11042714 | 258.090 | C8H4BrNO2S
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Medchemexpress LLC ER-27319 (maleate) | 1204480-26-1 | 99.4% | 396.44 | 1 ML
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ER-27319 (maleate) | 1204480-26-1 | 99.4% | 396.44 | 1 ML
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eMolecules 628-48-8 | TRANS-GLUTACONIC ACID | AstaTech | MFCD00002784 | 130.099 | C5H6O4 | 95.000 | OC(=O)C\C=C\C(O)=O | 0.25g | 718059738
TRANS-GLUTACONIC ACID | AstaTech | 628-48-8 | MFCD00002784 | 130.099 | C5H6O4 | 95.000 | OC(=O)C\C=C\C(O)=O | 0.25g | 718059738
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Medchemexpress LLC Ciproxifan (maleate) | 184025-19-2 | MFCD06411563 | 99.7% | 386.40 g/mol | C20H22N2O6 | 10 MG
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Ciproxifan maleate is a potent, selective, orally bioavailable competitive antagonist of the histamine H3 receptor supplied as a white to off-white powder for research use. It is used as an analytical standard and research reagent in neuroscience and aging-disease studies, with reported nanomolar potency.
- Potent H3 receptor antagonist (IC50 ≈ 9.2 nM)
- High purity (≈ 99.7%)
- Provided as a powdered maleate salt for stability and handling
- Suitable for neuroscience and Alzheimer's disease research
- Available in small pack sizes for analytical and screening use
- Includes CAS number 184025-19-2 and molecular weight 386.40 g/mol
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Medchemexpress LLC Indacaterol maleate | 753498-25-8 | 99.8% | C28H32N2O7 | 1 ML
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Indacaterol maleate is an orally active, ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. It functions by inhibiting NF-κB activity in a β-arrestin2-dependent manner. This chemical property contributes to preventing further lung damage and improving lung function in conditions like chronic obstructive pulmonary disorder (COPD). It also has potential applications in cardiovascular disease research.
- Acts as an ultra-long-acting β2 adrenergic receptor (ADRB2) agonist.
- Inhibits NF-κB activity via a β-arrestin2-dependent mechanism.
- Suppresses MMP-9 mRNA expression and activity.
- Reduces cell migration and inhibits NF-κB nuclear translocation.
- Active in normalizing cardiac remodeling in heart failure models.
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eMolecules 103-60-6 | 2-Phenoxyethyl isobutyrate | Ambeed | MFCD00027363 | 208.257 | C12H16O3 | 98.000 | CC(C)C(=O)OCCOc1ccccc1 | 25g | 490489950
2-Phenoxyethyl isobutyrate | Ambeed | 103-60-6 | MFCD00027363 | 208.257 | C12H16O3 | 98.000 | CC(C)C(=O)OCCOc1ccccc1 | 25g | 490489950
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Selleck Chemical LLC Timolol Maleate S4123-50mg
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Timolol Maleate (MK-950 (S)-Timolol Maleate) is a non-selective beta-adrenergic receptor antagonist for 1/ 2 with Ki of 1 97 nM/2 0 nM
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Selleck Chemical LLC Indacaterol Maleate S3083-1g
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Indacaterol (QAB149) is an ultra-long-acting -adrenoceptor agonist with pKi of 7 36 for 1-adrenoceptor and pKi of 5 48 for 2-adrenoceptor
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Selleck Chemical LLC Timolol Maleate S4123-1g
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Timolol Maleate (MK-950 (S)-Timolol Maleate) is a non-selective beta-adrenergic receptor antagonist for 1/ 2 with Ki of 1 97 nM/2 0 nM
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Medchemexpress LLC HY-B0516 100mg Medchemexpress, Articaine (hydrochloride) CAS:23964-57-0 Purity:>98%
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Medchemexpress, HY-B0516 100mg Articaine (hydrochloride) CAS:23964-57-0 Articaine hydrochloride (Hoe-045) is used in dental. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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