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Filtered Search Results
eMolecules 77758-51-1 | Methyl 5-hexynoate | Combi-Blocks | MFCD00671366 | 126.155 | C7H10O2 | 95.000 | COC(=O)CCCC#C | 1g | 415500572
Methyl 5-hexynoate | Combi-Blocks | 77758-51-1 | MFCD00671366 | 126.155 | C7H10O2 | 95.000 | COC(=O)CCCC#C | 1g | 415500572
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eMolecules 7283-69-4 | Diisobutyl fumarate | Combi-Blocks, Inc. | MFCD00152430 | 228.288 | C12H20O4 | 98.000 | CC(C)COC(=O)\C=C\C(=O)OCC(C)C | 25g | 603134297
Diisobutyl fumarate | Combi-Blocks, Inc. | 7283-69-4 | MFCD00152430 | 228.288 | C12H20O4 | 98.000 | CC(C)COC(=O)\C=C\C(=O)OCC(C)C | 25g | 603134297
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Apexbio Technology LLC NB-598 Maleate 155294-62-5 50mg
NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
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Apexbio Technology LLC Flupirtine maleate 75507-68-5 100mg
Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
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Medchemexpress LLC Avitinib maleate | 1557268-88-8 | 99.9% | 603.60 | 25 MG
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Avitinib maleate is a third-generation, irreversible, and orally active selective EGFR inhibitor. It has IC50 values of 0.18 nM against both EGFR L858R and EGFR T790M, and 7.68 nM against wild-type EGFR. It is also a BTK inhibitor, inducing apoptosis and inhibiting BTK phosphorylation in mantle cell lymphoma. It exhibits anticancer effects.
- Third-generation, irreversible, and orally active selective EGFR inhibitor.
- Potent against EGFR L858R, EGFR T790M, and wild-type EGFR.
- BTK inhibitor.
- Induces apoptosis.
- Inhibits phosphorylation of BTK in mantle cell lymphoma.
- Exhibits anticancer effects.
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Medchemexpress LLC Oleanolic acid hemiphthalate disodium salt | 168770-31-8 | 100 MG
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Oleanolic acid hemiphthalate disodium salt is a derivative of oleanolic acid with anti-inflammatory and potential anti-ulcer activities. It is intended for use as a laboratory chemical and in the manufacture of substances for research use only.
- Hemiphthalate derivative of oleanolic acid
- Exhibits anti-inflammatory activities
- Shows potential anti-ulcer activities
- Suitable for laboratory chemical applications
- Used in the manufacture of substances
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Medchemexpress LLC Bet bromodomain inhibitor 1 | 2411226-02-1 | 99.9% | C22H19F2N3O4S | 10MG
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BET bromodomain inhibitor 1 is an orally active, selective BET family bromodomain inhibitor used in epigenetic and anticancer research. It binds BRD4 with low-nanomolar potency and shows antiproliferative activity in multiple human cancer cell lines.
- Potent BRD4 inhibition (IC50 = 2.6 nM).
- Low-nanomolar binding to BET family members (Kd values ~1-3 nM).
- High purity (≈99.9%) suitable for research applications.
- Defined molecular formula C22H19F2N3O4S and molecular weight 459.47 g/mol.
- Demonstrated antiproliferative activity in cancer cell lines.
- Available in small research pack sizes and as a DMSO stock solution.
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Medchemexpress LLC PTP1B-IN-4 50 mg
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PTP1B-IN-4 50MG
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Medchemexpress LLC BET bromodomain inhibitor 1 | 2411226-02-1 | 99.7% | 50 MG
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BET bromodomain inhibitor 1 is an orally active, selective bromodomain and extra-terminal (BET) bromodomain inhibitor. It demonstrates high affinity binding to BRD2(2), BRD3(2), BRD4(1), BRD4(2), and BRDT(2) and exhibits potent anti-cancer activity.
- Orally active, selective BET bromodomain inhibitor
- IC50 of 2.6 nM for BRD4
- Binds to BRD2(2), BRD3(2), BRD4(1), BRD4(2), and BRDT(2) with high affinities
- Exhibits potent anti-cancer activity
- Induces G1-phase cell cycle arrest
- Inhibits c-Myc expression and upregulates p21 levels
- Reduces c-Myc, BCL-2, and CDK6 expressions
- Highly selective for BET bromodomain family (~1500-fold over EP300)
- Strong antitumor activities in MV4-11 mouse xenograft model
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eMolecules 1217457-86-7 | Medchem Express | GGTI298 (Trifluoroacetate) | 1mg | 446266818 | HY-15871 | MFCD06409252 | 593.66 | C29H34F3N3O5S
Medchem Express | GSK2656157 | 10mg | 446263575 | HY-13820 | 1337532-29-2 | MFCD27997885 | 416.460 | C23H21FN6O
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000743114 S-2-BENZYLSUCCINIC 5G
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Sigma Aldrich Fine Chemicals Biosciences Methyl 2-oxobutanoate 95% | 3952-66-7 | MFCD03093092 | 500G
Methyl 2-oxobutanoate 95% | Purity: >=95.0% (GC); 95% | Mol Wt: 116.12 | 3952-66-7 | MFCD03093092 | 500G
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MEDCHEMEXPRESS LLC L-CYSTEINE METHYL ESTER HYDRO
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501874312 L-CYSTEINE METHYL ESTER HYDRO
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Medchemexpress LLC 2-Benzylsuccinic acid | 884-33-3 | MFCD00055798 | 99.8% | 208.21 g/mol | C11H12O4 | 1 ML
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2-Benzylsuccinic acid is a small-molecule inhibitor of carboxypeptidase A and Nna1 supplied as a 10 mM solution in DMSO (1 mL). It is used in research on neuropathic pain (reduces cold hyperalgesia) and non-alcoholic steatohepatitis, and is provided at high purity for biochemical and pharmacological studies.
- Provided as a ready-to-use 10 mM solution in DMSO.
- High purity: 99.8%.
- CAS number 884-33-3 for unambiguous identification.
- Chemical formula C11H12O4 and molecular weight 208.21 g/mol.
- Intended for research on carboxypeptidase inhibition and neuropathic pain models.
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Medchemexpress LLC Z-YVAD-FMK | 210344-97-1 | 98.0% | 630.66 | 10 MG
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Z-YVAD-FMK is a cell-permeable caspase-1 and -4 inhibitor, demonstrating both anti-inflammatory and anti-tumor activities. It is intended for research use only and is not suitable for medical applications or sale to patients.
- Cell-permeable caspase-1 and -4 inhibitor
- Exhibits anti-inflammatory properties
- Demonstrates anti-tumor activities
- Suitable for various research applications
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