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Filtered Search Results
Apexbio Technology LLC CA 074 134448-10-5 5mg
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CA 074 (CAS 134448-10-5) is a selective inhibitor of cathepsin B a cysteine protease involved in diverse pathological mechanisms By targeting cathepsin B CA 074 alleviates neurotoxicity induced by amyloid-activated microglia and inhibits proteolytic cascades associated with cell growth suppression and plasminogen activation Additionally CA 074 treatment modulates immune responses by shifting CD4 T cells from a Th2 to a Th1 phenotype reducing IgE and IgG1 levels In vivo studies indicate that CA 074 can attenuate TNF- -induced hepatic injury highlighting its relevance as a research tool in inflammation immunology and neurodegenerative disease investigations
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eMolecules 919286-71-8 | (S)-tert-butyl 2-(broMoMethyl)Morpholine-4-carboxylate | MFCD20489339 | 1g
WuXi ChemSupply | (S)-tert-butyl 2-(broMoMethyl)Morpholine-4-carboxylate | 1g | 599165858 | LN00199757 | 95.000 | 919286-71-8 | MFCD20489339 | 280.162 | C10H18BrNO3
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Selleck Chemical LLC DL-Benzylsuccinic acid
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DL-Benzylsuccinic acid (2-benzylbutanedioic acid Benzylsuccinic acid) is a bacterial xenobiotic metabolite
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Chemscene ChemScene | Methyl benzimidazole-5-carboxylate | 25G | CS-W022885 | 0.98 | 26663-77-4| MFCD03407310 | 176.18
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ChemScene | Methyl benzimidazole-5-carboxylate | 25G | CS-W022885 | 0.98 | 26663-77-4| MFCD03407310 | 176.18
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Medchemexpress LLC 11beta-Hydroxyprogesterone | 600-57-7 | 5 MG
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11beta-Hydroxyprogesterone is a potent inhibitor of 11β-Hydroxysteroid dehydrogenase. It activates the human mineralocorticoid receptor in COS-7 cells (ED50 of 10 nM) and exhibits agonist mineralocorticoid activity by activating the transiently expressed human mineralocorticoid receptor (hMR) in COS-7 cells. Its agonist activity is linked to contacts between its 11β-hydroxyl group and Asn770 within the hMR-ligand-binding domain.
- Potent inhibitor of 11β-Hydroxysteroid dehydrogenase.
- Activates human mineralocorticoid receptor in COS-7 cells with an ED50 of 10 nM.
- Displays agonist mineralocorticoid activity.
- Exhibits hypertensinogenic activity in rats, dependent on an intact adrenal and mineralocorticoid receptor activation.
- Classified as an endogenous metabolite and a steroid.
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Accela Chembio Inc Methyl 3-methylthiophene-2-carboxylate | 5g | 81452-54-2 | MFCD00234332 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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Methyl 3-methylthiophene-2-carboxylate | 5g | 81452-54-2 | MFCD00234332 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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Medchemexpress LLC PTP1B-IN-3 | 809272-64-8 | C₁₂H₉BrF₂NOP | 5 MG
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PTP1B-IN-3 is a potent and orally active PTP1B inhibitor with IC50s of 120 nM for both PTP1B and TCPTP. It has antidiabetic and anticancer effects.
- Potent and orally active PTP1B inhibitor
- IC50 of 120 nM for PTP1B and TCPTP
- Exhibits antidiabetic effects
- Shows anticancer effects
- Good oral bioavailability in diet-induced obese (DIO) mice
- Slow clearance and good elimination half-life
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eMolecules 1664-34-2 | 1-Amino-cyclohexanecarboxylic acid ethyl ester | J & W PharmLab, LLC | MFCD10566110 | 171.240 | C9H17NO2 | 96.000 | CCOC(=O)C1(N)CCCCC1 | 5g | 249973556
1-Amino-cyclohexanecarboxylic acid ethyl ester | J & W PharmLab, LLC | 1664-34-2 | MFCD10566110 | 171.240 | C9H17NO2 | 96.000 | CCOC(=O)C1(N)CCCCC1 | 5g | 249973556
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Sigma Aldrich Fine Chemicals Biosciences Methyl acetate United States Pharmacopeia (USP) Reference Standard | 79-20-9 | MFCD00008711 | 3X1.2ML
Methyl acetate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 74.08 | 79-20-9 | MFCD00008711 | 3X1.2ML
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eMolecules 536718-30-6 | 2-(TRIFLUOROMETHYL)-3-FUROIC ACID | AstaTech | MFCD03662621 | 180.082 | C6H3F3O3 | 95.000 | OC(=O)c1ccoc1C(F)(F)F | 0.25g | 402180709
2-(TRIFLUOROMETHYL)-3-FUROIC ACID | AstaTech | 536718-30-6 | MFCD03662621 | 180.082 | C6H3F3O3 | 95.000 | OC(=O)c1ccoc1C(F)(F)F | 0.25g | 402180709
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![Medchemexpress LLC 8-Quinolinol, 7-[(3-ethoxy-4-methoxyphenyl)[(4-methyl-2-pyridinyl)amino]methyl]- | 430462-93-4 | 98.05% | 415.48 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000388123-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 8-Quinolinol, 7-[(3-ethoxy-4-methoxyphenyl)[(4-methyl-2-pyridinyl)amino]methyl]- | 430462-93-4 | 98.05% | 415.48 | 100 MG
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HQ-415 is a biologically active metal chelator related to Clioquinol, with an EC50 of 15 μM.
- Purity: 98.05%
- Molecular weight: 415.48
- Formula: C25H25N3O3
- CAS No.: 430462-93-4
- Appearance: Solid
- Color: White to off-white
- Shipping: Room temperature in continental US
- Storage: Powder -20°C for 3 years, 4°C for 2 years; In solvent -80°C for 2 years, -20°C for 1 year
- Solubility (In Vitro): DMSO : 5.6 mg/mL (13.48 mM; requires ultrasonic and warming; hygroscopic DMSO has a significant impact on solubility, use newly opened DMSO)
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Eagle Biosciences Inc Tau-381 1N3R Wild-Type Monomer, 100 ug
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Tau-381 (1N3R) Wild-Type Monomers
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=O | 1g | 495881470](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502167988.JPG-250.jpg)
eMolecules 96916-42-6 | Isopropenyl p-nitrophenyl carbonate | Synthonix - Stock | MFCD27935132 | 223.184 | C10H9NO5 | 95.000 | CC(=C)OC(=O)Oc1ccc(cc1)[N+]([O-])=O | 1g | 495881470
Isopropenyl p-nitrophenyl carbonate | Synthonix - Stock | 96916-42-6 | MFCD27935132 | 223.184 | C10H9NO5 | 95.000 | CC(=C)OC(=O)Oc1ccc(cc1)[N+]([O-])=O | 1g | 495881470
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eMolecules 36679-81-9 | 4-Hydroxymethyl-dihydro-furan-2-one | J & W PharmLab LLC | MFCD21099409 | 116.116 | C5H8O3 | 96.000 | OCC1COC(=O)C1 | 1g | 309209384
4-Hydroxymethyl-dihydro-furan-2-one | J & W PharmLab LLC | 36679-81-9 | MFCD21099409 | 116.116 | C5H8O3 | 96.000 | OCC1COC(=O)C1 | 1g | 309209384
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eMolecules BENZYL PROPIOLATE 1G
5000189018 BENZYL PROPIOLATE 1G
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