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Filtered Search Results
Selleck Chemical LLC Dimethindene maleate-100MG
Dimethindene maleate is a selective antagonist of histamine H1 and exhibits antihistamine effects It suppresses the cromakalim-induced/glibenclamide-sensitive K currents in a concentration-dependent and reversible manner
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eMolecules 922-67-8 | Methyl propiolate | AA Blocks LLC | MFCD00008572 | 84.074 | C4H4O2 | 0.000 | COC(=O)C#C | 10g | 448665143
Methyl propiolate | AA Blocks LLC | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 0.000 | COC(=O)C#C | 10g | 448665143
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Medchemexpress LLC ER-27319 (maleate) | 1204480-26-1 | 99.4% | 396.44 | 50 MG
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ER-27319 (maleate), an acridone derivative, is a potent and selective SYK inhibitor. It inhibits the tyrosine phosphorylation of SYK and its activity, and can be used for study in allergic diseases. It also inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM.
- Potent and selective SYK inhibitor
- Inhibits tyrosine phosphorylation of SYK
- Inhibits release of antigen-induced allergic mediators
- Suitable for study in allergic diseases
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Medchemexpress LLC Zamifenacin fumarate | 127308-98-9 | 99.0% | 531.60 g/mol | C31H33NO7 | 5 MG
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Zamifenacin fumarate is the fumarate salt of zamifenacin (UK-76654), a gut-selective muscarinic M3 receptor antagonist used in research to study gastrointestinal motility. It is provided as a high-purity solid for use in in vitro and in vivo pharmacology studies targeting colonic motility.
- Potent gut-selective muscarinic M3 receptor antagonist that reduces colonic motility.
- High purity suitable for research applications (99.0%).
- Solid, white to off-white form for convenient handling and dosing.
- Molecular weight 531.60 g/mol, molecular formula C31H33NO7.
- Recommended storage at 4°C; in solution, -80°C for long-term stability.
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eMolecules 1120360-13-5 | Glyceryl ascorbate | Chem-Impex250.203 | C9H14O8 | 97.000 | OCC(O)COC1=C(O)C(OC1=O)C(O)CO | 1g | 490842859
Glyceryl ascorbate | Chem-Impex | 1120360-13-5250.203 | C9H14O8 | 97.000 | OCC(O)COC1=C(O)C(OC1=O)C(O)CO | 1g | 490842859
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Apexbio Technology LLC Flupirtine maleate 75507-68-5 10mM (in 1mL DMSO)
Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
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Medchemexpress LLC (S)-Timolol (Maleate) | 26921-17-5 | 99.8% | 432.49 | 25 MG
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(S)-Timolol maleate is a non-cardioselective hydrophilic β-adrenoceptor blocker, widely used as a standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. It also finds application in hypertension, angina pectoris, and myocardial infarction. This product is suitable for research and analytical applications.
- Non-cardioselective hydrophilic β-adrenoceptor blocker
- Prevents production of aqueous humor
- Used for intraocular pressure (glaucoma)
- Can be used for hypertension
- Can be used for angina pectoris
- Can be used for myocardial infarction
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Apexbio Technology LLC Rosiglitazone maleate(Synonyms: Avandia, BRL 49653, BRL49653C, Rosiglitazone maleate salt, BRL49653, RGZ, Rosiglizole maleate), 25mg, CAS: 155141-29-0.
Rosiglitazone maleate (CAS 155141-29-0) is the maleate salt formulation of rosiglitazone a thiazolidinedione compound targeting the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR ) By selective activation of PPAR rosiglitazone increases insulin sensitivity of peripheral tissues facilitating glucose uptake and reduction of blood glucose levels Due to its insulin-sensitizing activity rosiglitazone maleate serves as an important research tool in diabetes and metabolic syndrome investigations However recent clinical studies also report associations with adverse cardiovascular events fluid retention and anemia underscoring considerations for risk-benefit evaluation in ongoing research
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eMolecules 1588440-89-4 | 4-(Aminomethyl)-7-methoxy-3,4-dihydroquinolin-2(1H)-one hydrochloride | MFCD27920873 | 250mg
Ambeed | Dibenzo[bd]thiophene-2-carbaldehyde | 1g | 600827214 | A108182 | 22099-23-6 | MFCD02251670 | 212.270 | C13H8OS
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Medchemexpress LLC Sultamicillin | 76497-13-7 | 50 MG
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Sultamicillin is a broad-spectrum, orally active beta-lactamase inhibitor and an antibiotic with antibacterial activity. It is for research use only and exhibits antibacterial activity even against MRSA.
- Broad-spectrum beta-lactamase inhibitor
- Orally active antibiotic
- Exhibits antibacterial activity, including against MRSA
- Hydrolyzed to Sulbactam and Ampicillin upon oral absorption
- Can improve survival in experimental polymicrobial sepsis in mice when combined with immunosuppression agents
- Enhances bacterial clearance
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eMolecules CEFCAPENE PIVOXIL HCL | 147816-23-7 | | 1g
AstaTech | CEFCAPENE PIVOXIL HCL | 1g | 213339658 | 83157 | 95.000 | 147816-23-7 | | 604.090 | C23H30ClN5O8S2
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AdipoGen Dihydrofluorescein diacetate
Chemical. CAS 35340-49-9. Formula C24H18O7. MW 418.4. Synthetic. Dihydrofluorescein diacetate is a fluorescent probe for detecting intracellular oxidants. It is hydrolyzed by cellular esterases to dihydrofluorescein and is then oxidized to fluorescein primarily by H2O2. Dihydrofluorescein diacetate might be reactive toward a broad range of oxidizing reactions that may be increased during intracellular oxidant stress. Cell-loading studies indicate that dihydrofluorescein achieves higher intracellular concentrations than the other redox sensors such as Dihydrorhodamine 123 Ex/Em 490/514nm.
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eMolecules 863971-12-4 | MMAF-methyl ester | Broadpharm | MFCD30535529 | 746.003 | C40H67N5O8 | 98.000 | CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C | 10mg | 445408910
MMAF-methyl ester | Broadpharm | 863971-12-4 | MFCD30535529 | 746.003 | C40H67N5O8 | 98.000 | CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C | 10mg | 445408910
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Apexbio Technology LLC CA 074 134448-10-5 1mg
CA 074 (CAS 134448-10-5) is a selective inhibitor of cathepsin B a cysteine protease involved in diverse pathological mechanisms By targeting cathepsin B CA 074 alleviates neurotoxicity induced by amyloid-activated microglia and inhibits proteolytic cascades associated with cell growth suppression and plasminogen activation Additionally CA 074 treatment modulates immune responses by shifting CD4 T cells from a Th2 to a Th1 phenotype reducing IgE and IgG1 levels In vivo studies indicate that CA 074 can attenuate TNF- -induced hepatic injury highlighting its relevance as a research tool in inflammation immunology and neurodegenerative disease investigations
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Cayman Chemical CA-074 methyl ester 500ug
A cell-permeable inhibitor of cathepsin B and L in vivo and in whole cells; used to study the role of cathepsin B in neurodegeneration, cancer cell metastasis, necrosis, and rheumatoid arthritis
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