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Filtered Search Results
Medchemexpress LLC U-99194 (maleate) | 234757-41-6 | 99.2% | 25 MG
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U-99194 maleate is a selective, potent dopamine D3 receptor antagonist with a Kᵢ of 160 nM. It inhibits the activation of the D3 receptor mediated by endogenously released dopamine or exogenous D3 agonists. This compound can be used for the study of dopamine D3 receptor-mediated motor disorders, particularly kinetic tremors.
- Selective, potent dopamine D3 receptor antagonist
- Inhibits activation of D3 receptor
- Abrogates the IPSC-suppressive effect of D3 agonists
- Significantly suppresses Nicotine-induced tremor in mice
- Useful for studying dopamine D3 receptor-mediated motor disorders
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Medchemexpress LLC Ro 25-6981 Maleate | 1312991-76-6 | 99.25% | 455.54 | 100 MG
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Ro 25-6981 Maleate is a potent, selective, and activity-dependent NR2B subunit-specific NMDA receptor antagonist. It demonstrates anticonvulsant and anti-parkinsonian activity and has potential for research into Parkinson's disease.
- Potent, selective, and activity-dependent NR2B subunit-specific NMDA receptor antagonist
- Demonstrates anticonvulsant activity
- Demonstrates anti-parkinsonian activity
- Potential for Parkinson's disease research
- Induces contraversive rotations in 6-OHDA-lesioned rats
- Exhibits age- and activation-dependent anticonvulsant action
- Shows analgesic effects on incision pain in rats
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Apexbio Technology LLC CARBINOXAMINE-MALEATE-100MG
CarbinoxaMine Maleate (CAS No 3505-38-2) is an antihistamine often studied in biomedical research for its role in allergy and respiratory studies Originating from first-generation antihistamines it primarily targets H1 histamine receptors inhibiting the action of histamine in allergic reactions Its mechanism of action involves blocking the receptors reducing symptoms like itching swelling and runny noses In vitro studies frequently show activity in the nanomolar to low micromolar range demonstrating its potency in these controlled settings Common applications of CarbinoxaMine Maleate include use in cell models to evaluate histamine-related responses animal studies for allergy and inflammation research and drug screening to assess antihistamine candidates Experimental concentrations typically depend on the specific research design allowing flexibility based on the study s objectives and requirements
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Medchemexpress LLC Zamifenacin fumarate | 127308-98-9 | 99.0% | 531.60 g·mol^-1 | C31H33NO7 | 50 MG
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Zamifenacin fumarate is a gut-selective muscarinic M3 receptor antagonist used in research to reduce colonic motility. Supplied as a high-purity solid, it is intended for laboratory pharmacology and GPCR signaling studies.
- Gut-selective muscarinic M3 receptor antagonist for research use.
- Shown to reduce colonic motility in preclinical studies.
- High reported purity (99.0%).
- Solid, white to off-white appearance suitable for analytical handling.
- Available in multiple pack sizes, including 50 MG.
- Store sealed and away from moisture; recommended refrigerated storage and defined solution storage temperatures.
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Medchemexpress LLC BGT226 MALEATE 100 mg
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BGT226 MALEATE 100MG
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Medchemexpress LLC MEPYRAMINE MALEATE 1G
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MEPYRAMINE MALEATE 1G
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Medchemexpress LLC MEPYRAMINE MALEATE 50 mg
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MEPYRAMINE MALEATE 50MG
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Medchemexpress LLC Filgotinib maleate | 1802998-75-9 | MFCD34184747 | 99.9% | 541.58 | C25H27N5O7S | 10 MG
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Filgotinib maleate is the maleate salt of filgotinib, a selective, orally active JAK1 inhibitor supplied as a high-purity research reagent for studying inflammatory and antiviral pathways. Provided as a 10 mg solid, it is intended for laboratory use with recommended storage conditions noted on the product datasheet and SDS.
- Selective JAK1 inhibitor for research applications.
- Maleate salt form for improved solubility.
- High purity suitable for analytical and biological studies.
- 10 mg solid package convenient for small-scale experiments.
- Recommended storage: solid 4°C; in solvent -80°C up to 6 months.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000296915 PD-168077 MALEATE 10MG
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Medchemexpress LLC Avitinib maleate | 1557268-88-8 | MFCD29089376 | 99.9% | 603.60 | C30H30FN7O6 | 10 MG
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Avitinib maleate is a third-generation, irreversible, orally active EGFR inhibitor supplied as the maleate salt for research use. It exhibits potent activity against EGFR L858R and T790M mutations, with reported BTK inhibitory activity, and is provided with analytical data confirming high purity. Typical formats include small solid quantities and DMSO solutions for laboratory studies.
- Third-generation, irreversible EGFR inhibitor suitable for targeted research.
- Potent activity against EGFR L858R and T790M mutants.
- Reduced potency against wild-type EGFR to aid selectivity studies.
- Maleate salt form for improved handling and stability.
- High purity with RP-HPLC documentation.
- Available in small solid pack sizes and solution formats for assays.
- Intended for in vitro and preclinical research applications.
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eMolecules 922-67-8 | Methyl propiolate | Ambeed | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 1g | 525200920
Methyl propiolate | Ambeed | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 1g | 525200920
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eMolecules 79218-15-8 | TERT-BUTYL CROTONATE | AstaTech | MFCD00059055 | 142.198 | C8H14O2 | 95.000 | C\C=C\C(=O)OC(C)(C)C | 1g | 718082882
TERT-BUTYL CROTONATE | AstaTech | 79218-15-8 | MFCD00059055 | 142.198 | C8H14O2 | 95.000 | C\C=C\C(=O)OC(C)(C)C | 1g | 718082882
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Medchemexpress LLC ODN 2216 | 332437-00-0 | DNA, d(G-sp-G-sp-G-G-G-A-C-G-A-T-C-G-T-C-G-sp-G-sp-G-sp-G-sp-G-sp-G) | 1 MG
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ODN 2216 is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. It induces high amounts of IFN-α and IFN-β, and IFN-α by pDC (plasmacytoid DC) and IL-12 (p40) production by DC (dendritic cells). It stimulates IFN-γ production in peripheral blood mononuclear cells (PBMC), indirectly mediated by IFN-α/β.
- Activates NK cells and promotes IFN-γ production of TCR-triggered CD4+ T cells.
- Drives Th1 development of naive CD4 T cells.
- Significantly decreases apoptosis of thymic DC.
- Induces T-cell mediated antitumor immune response in murine vaccination models.
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eMolecules 922-67-8 | Methyl propiolate | Ambeed | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 10g | 552720843
Methyl propiolate | Ambeed | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 10g | 552720843
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Accela Chembio Inc Diethyl Isopropylidenemalonate | 100g | 6802-75-1 | MFCD00009147 | 95% | D: 1.021 | Shelf Life: 540 Days |
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Diethyl Isopropylidenemalonate | 100g | 6802-75-1 | MFCD00009147 | 95% | D: 1.021 | Shelf Life: 540 Days |
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