Dicarboxylic acids and derivatives
Medchemexpress LLC PKUMDL-LC-101-D04 100mg | 2143896-83-5 | 378.9 | C14H22N4O2S2 · HCl | 100 MG
PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) used in research to modulate ferroptosis and lipid-peroxide-mediated cell death. It increases GPX4 enzymatic activity in biochemical assays and has demonstrated activity in cell extracts and cellular protection assays.
- Allosteric activator of glutathione peroxidase 4.
- Increases GPX4 activity to about 150% in a cell-free assay at 20 μM.
- Restores GPX4 activity in cell extracts at 61 μM.
- Reduces cholesterol hydroperoxide-induced cell death in mouse embryonic fibroblasts.
- High purity research-grade material suitable for biochemical and cellular assays.
- Molecular weight 378.9 and formula C14H22N4O2S2 · HCl.
Medchemexpress LLC 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | 99.1% | 434.49 g/mol | C24H26N4O4 | 1 ML
CUDC-101 is a small-molecule inhibitor that targets histone deacetylases (HDAC) and receptor tyrosine kinases EGFR and HER2. It is intended for research use in studies of signaling pathways, anti-proliferative activity, and preclinical cancer models. The compound is supplied as a high-purity reagent suitable for in vitro experiments.
- Multi-target HDAC, EGFR, and HER2 inhibition
- High purity suitable for research applications
- Available as a ready-to-use 10 mM solution in DMSO (1 mL)
- Confirmed molecular formula and molecular weight for analytical workflows
- Intended for in vitro and preclinical research use
Medchemexpress LLC Lauroyl-L-carnitine-d9 chloride | 2245711-25-3 | MFCD34676545 | 98.0% | 389.02 g/mol | C19H29D9ClNO4 | 5 MG
Lauroyl-L-carnitine-d9 chloride is the deuterium-labeled chloride salt of lauroyl-L-carnitine supplied for analytical and tracer applications. It is intended for use as a stable-isotope internal standard in bioanalytical, pharmacokinetic, and tracer studies where mass spectrometry differentiation is required.
- Stable isotope labeled internal standard for mass spectrometry
- Deuterated (d9) for clear mass separation from native compound
- High purity (98.0%) suitable for analytical workflows
- Chloride salt form for compatibility with common assays
- Supplied in a 5 mg quantity for small-scale analyses
Medchemexpress LLC AVN-101 hydrochlorid 10mg | 1061354-48-0 | 340.89 | C21H25ClN2 | 10 MG
AVN-101 hydrochloride is the hydrochloride salt of AVN-101, a brain-penetrant, orally active antagonist of serotonin 5-HT7 receptors used in preclinical CNS research. It is supplied as a high-purity solid for in vitro and in vivo studies.
- Potent 5-HT7 receptor antagonist with additional activity at 5-HT6, 5-HT2A, 5-HT2C, H1, and α2 adrenergic receptors.
- Brain-penetrant and orally active, suitable for CNS pharmacology studies.
- High purity solid (LCMS purity 99.59%) for reliable experimental results.
- Chemical identity: 1H-pyrido[4,3-b]indole hydrochloride; formula C21H25ClN2; Mw 340.89.
- Recommended storage: sealed at -20°C; solvent storage guidance available from supplier.
![Medchemexpress LLC O=C([C@]1(CO1)CO[Si](C)(C)C(C)(C)C)[C@H](CC(C)C)NC([C@H](C)NC(CCCCCC)=O)=O | 1000313-40-5 | 99.6% | 484.74 | C25H48N2O5Si | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000229462.png-250.jpg)
Medchemexpress LLC O=C([C@]1(CO1)CO[Si](C)(C)C(C)(C)C)[C@H](CC(C)C)NC([C@H](C)NC(CCCCCC)=O)=O | 1000313-40-5 | 99.6% | 484.74 | C25H48N2O5Si | 5 MG
UK-101 is a selective immunoproteasome β1i (LMP2) inhibitor for laboratory research. It shows reported potency with an IC50 of about 104 nM and is supplied as a high-purity solid suitable for in vitro studies; recommended solvent is DMSO.
- Selective immunoproteasome β1i (LMP2) inhibitor with IC50 ≈104 nM.
- High purity (≈99.6%).
- Available in small research quantities, e.g., 5 mg.
- Recommended solvent: DMSO for dissolution.
- Powder storage: -20°C (3 years) or 4°C (2 years); solutions: -80°C (6 months).
- For research use only; not for human or clinical use.
Medchemexpress LLC Lauroyl-L-carnitine chloride | 6919-91-1 | 98.1% | 1 ML
Lauroyl-L-carnitine chloride is an orally active metabolite that significantly reverses the decrease in its target gene IL-10 and alleviates Crohn's-like colitis. This product is for research use only.
- Orally active metabolite
- Reverses decrease in IL-10
- Alleviates Crohn's-like colitis
- Exhibits anti-inflammatory effects
- Improves systemic and local phenotypes of TNBS mice
Medchemexpress LLC Lauroyl-L-carnitine (chloride) | 6919-91-1 | 98.1% | 25 MG
Lauroyl-L-carnitine chloride is an orally active metabolite. It significantly reverses the decrease in its target gene IL-10 and alleviates Crohn's-like colitis.
- Orally active metabolite
- Reverses decrease in IL-10 gene
- Alleviates Crohn's-like colitis
- Purity: 98.14%
Medchemexpress LLC 1,2-Dilauroyl-sn-glycerol | 60562-15-4 | 98.0% | 25 MG
1,2-Dilauroyl-sn-glycerol is a saturated diacylglycerol that may participate in second messenger signal transduction. It is intended for research use only and is not sold to patients.
- Potential role in second messenger signal transduction.
- Crucial intracellular signaling molecules involved in regulating various physiological processes.
- Specifically designated for research purposes.
Medchemexpress LLC 1,2-Dilauroyl-sn-glycerol | 60562-15-4 | 98.0% | 50 MG
1,2-Dilauroyl-sn-glycerol is a saturated diacylglycerol that may be involved in second messenger signal transduction. It appears as a white to off-white solid with a molecular formula of C27H52O5 and a molecular weight of 456.70. This product is intended for research use only.
- Purity of 98.0%
- CAS number: 60562-15-4
- Soluble in DMSO (100 mg/mL), requiring ultrasonic for dissolution
- Ships at room temperature within the continental US
- Recommended storage for powder: -20°C for 3 years
- Recommended storage for in-solvent solutions: -80°C for 6 months, or -20°C for 1 month (aliquot and store to prevent inactivation from repeated freeze-thaw cycles)
- Related to metabolic enzymes/proteases and endogenous metabolites
- Acts as an inhibitor
Medchemexpress LLC UK-101 | 1000313-40-5 | 99.6% | 484.74 g/mol | C25H48N2O5Si | 25 MG
UK-101 is a potent, selective immunoproteasome β1i (LMP2) inhibitor intended for research use. It has a reported IC50 of 104 nM against LMP2, with significant selectivity over the constitutive β1c and β5 proteasome subunits. UK-101 is used in cell-based studies to induce apoptosis and to investigate immunoproteasome function and cancer-related pathways. Supplied as a powder with recommended storage conditions to preserve stability.
- Potent LMP2 (β1i) inhibitor with IC50 ≈ 104 nM.
- Selective over proteasome β1c and β5 subunits.
- Induces apoptosis in cell-based assays.
- High purity suitable for biochemical and cellular studies.
- Supplied as powder with recommended storage for long-term stability.
Medchemexpress LLC Lauroyl-L-carnitine (chloride) | 6919-91-1 | 98.1% | 1 MG
Lauroyl-L-carnitine chloride is an orally active metabolite that significantly reverses the decrease in its target gene IL-10, alleviating Crohn's-like colitis. It demonstrates anti-inflammatory effects and improves both systemic and local phenotypes in TNBS mice.
- Orally active metabolite
- Reverses decrease in target gene IL-10
- Alleviates Crohn's-like colitis
- Exhibits anti-inflammatory effects
- Improves systemic and local phenotypes in TNBS mice
Medchemexpress LLC Lauroyl-L-carnitine chloride | 6919-91-1 | MFCD00274131 | 98.1% | C19H38ClNO4 | 10MG
Lauroyl-L-carnitine chloride is an orally active absorption enhancer used in research to improve the oral bioavailability of peptide compounds. Supplied as a white to off-white solid with high purity, it is applied in formulation and permeability studies to assess and enhance intestinal uptake of peptide drugs.
- Orally active absorption enhancer for peptide compounds.
- Reported to improve oral bioavailability of peptides.
- White to off-white solid suitable for formulation research.
- High purity (~98.1%) as supplied.
- Supports studies of intestinal permeability and delivery.
- Store sealed at 4°C; in solvent, -80°C (6 months) or -20°C (1 month).