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Organic compounds that contain two carboxyl groups; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from dicarboxylic acids.
PHI-101 is an orally active potent third-generation inhibitor of FLT3 that overcomes resistance to multiple drug-resistant mutations It has potential for research in relapsed or refractory acute myeloid leukemia (AML)
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Sulforhodamine 101 (60311-02-6) is a red-emitting fluorescent dye primarily utilized as a selective marker for astrocytes Sulforhodamine 101 selectively accumulates in astrocytes enabling differentiation from surrounding neuronal populations In neurobiological studies using live tissue imaging including acute brain slice preparations the dye facilitates visualization of astroglial cell morphology and cellular dynamics Based on these properties Sulforhodamine 101 holds research potential in the study of astrocyte-specific responses morphological characteristics and cell cell interactions within neuronal tissues
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LEI-101 is a potent, selective cannabinoid CB2 receptor agonist used for biochemical and pharmacological research. It shows high selectivity for CB2 over CB1, is orally bioavailable, and is supplied as a solid for laboratory studies. Intended for research use only (not for human use).
Selective CB2 receptor agonist with approximately 100-fold selectivity over CB1.
Orally bioavailable, suitable for in vivo pharmacology studies.
High purity (99.35%).
Molecular weight 508.99 and formula C23H26ClFN4O4S.
Soluble in DMSO (approx. 116.7 mg/mL).
Intended for laboratory research use only, not for human consumption.
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PKUMDL-LC-101-D04 (CAS 2143896-83-5) is a small molecule allosteric activator of glutathione peroxidase 4 (GPX4) a key enzyme regulating ferroptosis In biochemical and cell extract assays PKUMDL-LC-101-D04 enhances GPX4 activity to 150% of baseline at concentrations of 20 M and 61 M respectively This compound serves as a valuable tool for investigating the modulation of ferroptosis through GPX4 activation and supports research into oxidative stress and cell death mechanisms
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UK-101 is a selective small-molecule inhibitor of the immunoproteasome β1i (LMP2) subunit used in biochemical and cellular research to probe immunoproteasome function and induce apoptosis in certain cancer models.
Selective LMP2 (β1i) inhibitor with reported IC50 of 104 nM.
Shows ~144-fold selectivity versus β1c and ~10-fold versus β5.
High reported purity (99.58%) suitable for research applications.
Molecular weight 484.74 g·mol⁻¹ and formula C25H48N2O5Si.
Soluble in DMSO and supplied in small research quantities, including 1 mg packs.
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GlyH-101 is a research-grade small-molecule inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR). It is used in cellular and electrophysiological studies to block CFTR-mediated chloride conductance and has reported antiproliferative activity. Supplied as a purified, characterized compound for laboratory research.
Potent CFTR inhibitor for cellular and electrophysiology assays.
Reversible blockade of VSORC conductance.
High purity (99.7%).
Molecular weight 493.15 g/mol.
Molecular formula C19H15Br2N3O3.
Supplied as a 10 mg vial for research use.
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