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Organic compounds that contain two carboxyl groups; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from dicarboxylic acids.
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MZ-101 (GYS1-IN-2) is a potent small molecule inhibitor of Glycogen synthase 1(GYS1) with an IC50 value of 0 041 M By depleting muscle glycogen MZ-101 treatment normalizes glycogen levels and corrects transcriptional and metabolic abnormalities in Pompe mice
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
MZ-101 (GYS1-IN-2) is a potent small molecule inhibitor of Glycogen synthase 1(GYS1) with an IC50 value of 0 041 M By depleting muscle glycogen MZ-101 treatment normalizes glycogen levels and corrects transcriptional and metabolic abnormalities in Pompe mice
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
UK-101 is a potent, selective inhibitor of the immunoproteasome β1i (LMP2) subunit used as a biochemical probe to study immunoproteasome activity and apoptosis-related pathways.
Potent LMP2 inhibition (IC50 ≈ 104 nM).
High selectivity versus β1c and β5 subunits.
High purity suitable for research use (≈99.6%).
Soluble in DMSO (≈7.3 mg/mL); may require warming or sonication.
Supplied in small quantities appropriate for laboratory assays.
Commonly used in biochemical assays and apoptosis research.
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Sulforhodamine 101 DHPE is a red fluorescent phospholipid probe created by conjugating dipalmitoyl phosphoethanolamine to sulforhodamine 101. It readily incorporates into lipid bilayers and is used for membrane imaging, monitoring probe colocalization in liposomes, and detecting protein-ligand interactions on supported bilayers. The dye exhibits excitation/emission peaks near 586/605 nm and is supplied as a powder with recommended cold storage.
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ULK-101 is a potent, selective small-molecule inhibitor of Unc-51-like autophagy-activating kinase 1 (ULK1) that suppresses autophagy and sensitizes cancer cells to nutrient stress. It is characterized in vitro with low-nanomolar activity against ULK1 and shows activity versus ULK2. Supplied as a powder for laboratory research use only.
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