Dicarboxylic acids and derivatives
Sigma Aldrich Luperox™ TBEC, tert-Butylperoxy 2-ethylhexyl carbonate
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Luperox™ A75, Benzoyl peroxide
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich Luperox™ LP, Lauroyl peroxide
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Medchemexpress LLC VH 101, acid | 2408341-97-7 | 98.8% | 574.66 | C28H35FN4O6S | 10 MG
VH 101, acid is a functionalized von Hippel-Lindau (VHL) E3 ligase ligand developed for PROTAC research and conjugation chemistry. The molecule includes an E3 ligase recognition motif and an alkyl linker terminating in a primary amine, facilitating attachment to target protein ligands.
- Designed for use as a VHL E3 ligase ligand in PROTAC development.
- Alkyl linker with terminal amine enables straightforward conjugation chemistry.
- High reported purity suitable for research applications.
- Supplied in small research-scale quantities for synthetic work and assay testing.
Medchemexpress LLC VH 101, acid | 2408341-97-7 | 98.8% | C28H35FN4O6S | 25 MG
VH 101, acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. It contains an E3 ligase ligand plus an alkyl linker with a terminal amine, making it ready for conjugation to a target protein ligand.
- Functionalized von-Hippel-Lindau (VHL) protein ligand
- For PROTAC research and development
- Contains an E3 ligase ligand
- Alkyl linker with terminal amine for conjugation
- VHL protein is a substrate recognition subunit of Cullin RING E3 ubiquitin ligase complexes
- Used by bifunctional Proteolysis-targeting chimeras (PROTACs) to induce ubiquitination and subsequent proteasomal degradation of a target protein
Apexbio Technology LLC AT-101 90141-22-3 50mg
AT-101 (CAS 90141-22-3) is a natural BH3-mimetic isolated from cottonseed identified as a pan-inhibitor of the anti-apoptotic proteins Bcl-2 Bcl-xL and Mcl-1 Mechanistically AT-101 binds to the hydrophobic BH3-binding grooves of these Bcl-2 family proteins impeding their heterodimerization with pro-apoptotic members (e g Bad Bid and Bim) thereby restoring apoptotic signaling pathways It has been shown to promote apoptosis in cell-based assays via caspase-9 activation and modulation of Puma Noxa Bax and XIAP protein expression Preclinical studies demonstrate anti-tumor activity in prostate cancer xenografts AT-101 is currently evaluated in clinical trials against castration-resistant prostate cancer and other cancers
![Medchemexpress LLC Benzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl] | 831217-40-4 | 98.2% | 931.12 g/mol | C54H66N4O10 | 1MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238871.png-250.jpg)
Medchemexpress LLC Benzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl] | 831217-40-4 | 98.2% | 931.12 g/mol | C54H66N4O10 | 1MG
MAL3-101 is a small-molecule allosteric inhibitor of heat shock protein 70 (HSP70) used in cellular and biochemical research. It inhibits HSP70 ATPase activity by blocking interaction with Hsp40 co-chaperones, perturbing protein folding and proteostasis pathways. The compound is supplied as a high-purity research reagent (CAS 831217-40-4) and is intended for in vitro and preclinical studies only.
- Allosteric inhibitor of HSP70 ATPase activity.
- Blocks Hsp40-Hsp70 interaction to disrupt protein folding.
- Applicable to cellular models studying proteostasis and cancer biology.
- High reported purity supports reproducible results.
- Supplied in small quantities suitable for screening and pilot studies.
- For research use only; not for human or veterinary use.
TARGETMOL CHEMICALS INC KHS 101 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation. Purity 98%
Medchemexpress LLC Vnt-101 | 2894060-67-2 | 456.41 | C21H23F3N2O6 | 10 MG
VNT-101 is a small-molecule, orally active inhibitor of influenza A virus nucleoprotein (NP) oligomerization. It disrupts NP-NP protein-protein interactions to destabilize the viral ribonucleoprotein complex and has been used in vitro and in vivo to study antiviral activity across multiple influenza A subtypes.
- Disrupts nucleoprotein oligomerization to inhibit viral replication.
- Orally bioavailable small molecule suitable for in vivo studies.
- Demonstrated activity against multiple influenza A subtypes.
- Molecular weight 456.41 and molecular formula C21H23F3N2O6.
- CAS number 2894060-67-2 for substance identification.
- Supplied as a solid for research use with supporting characterization data.
Medchemexpress LLC Sulforhodamine 101 DHPE | 187099-99-6 | >95.0% | 1381.84 | C74H117N4O14PS2 | 1MG
Sulforhodamine 101 DHPE is a red fluorescent phospholipid probe created by conjugating dipalmitoyl phosphoethanolamine to sulforhodamine 101. It readily incorporates into lipid bilayers and is used for membrane imaging, monitoring probe colocalization in liposomes, and detecting protein-ligand interactions on supported bilayers. The dye exhibits excitation/emission peaks near 586/605 nm and is supplied as a powder with recommended cold storage.