Pyrazoles
Medchemexpress LLC RecR E.coli His-SU 5ug
Recombinant RecR protein from Escherichia coli, supplied lyophilized and expressed with an N-terminal SUMO and 6xHis tag. The product corresponds to residues M1-F201, has an approximate molecular weight of 38.0 kDa, and a stated purity of 96% by reducing SDS-PAGE. Lyophilized from 20 mM Tris-HCl, 0.5 M NaCl, 6% trehalose (pH 8.0); store lyophilized at -20°C and reconstitute to at least 100 μg/mL in ddH2O for use. Recommended post-reconstitution storage and aliquoting guidance are provided for long-term stability.
- Expressed in Escherichia coli with N-terminal SUMO and 6xHis tags.
- Covers residues M1-F201 for full-length RecR analysis.
- Approximately 38.0 kDa molecular weight for characterization.
- High purity (96%) suitable for biochemical and binding assays.
- Lyophilized formulation with trehalose to enhance stability.
- Storage and reconstitution guidance provided for reliable handling.
Medchemexpress LLC Phthalazinone pyrazole | 880487-62-7 | MFCD28399120 | 98.0% | 317.34 | C18H15N5O | 5MG
Phthalazinone pyrazole is a small-molecule Aurora-A kinase inhibitor used in research on cell cycle regulation, apoptosis, and mitosis. It is supplied as a solid and as a DMSO solution for biochemical and cellular assays.
- Potent Aurora-A kinase inhibitor for research use.
- Molecular formula C18H15N5O, molecular weight 317.34 g·mol⁻¹.
- Purity ≥98.0% by HPLC.
- Available as solid (5 mg-100 mg) and solution (10 mM in DMSO, 1 mL).
- Store at 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
- Provided with datasheet, SDS, and COA for characterization.
eMolecules 761446-44-0 | 1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-1H-Pyrazole | AA Blocks LLC | MFCD03789259 | 208.070 | C10H17BN2O2 | 0.000 | Cn1cc(cn1)B1OC(C)(C)C(C)(C)O1 | 250g | 846251707
1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-1H-Pyrazole | AA Blocks LLC | 761446-44-0 | MFCD03789259 | 208.070 | C10H17BN2O2 | 0.000 | Cn1cc(cn1)B1OC(C)(C)C(C)(C)O1 | 250g | 846251707
Medchemexpress LLC 1H-pyrazole, 1-(methyl-d3)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- | 1022151-50-3 | ≥98.0% | 211.08 g/mol | C10H14D3BN2O2 | 100 MG
1-Methyl-1H-pyrazole-4-boronic acid pinacol ester-d3 is a deuterium-labeled boronic ester supplied as a high-purity research reagent for use as an isotope-labeled building block, tracer, and analytical standard in synthetic and analytical chemistry. It is intended for method development, quantitative analysis, and incorporation into cross-coupling workflows.
- Deuterium-labeled (d3) boronic ester suitable as tracer and internal standard.
- Purity ≥98.0%.
- Molecular formula C10H14D3BN2O2; molecular weight 211.08 g/mol.
- Available in small-scale packages such as 100 mg.
- Supplied with COA and SDS for batch-specific documentation.
- Functional pinacol boronate enables Suzuki-Miyaura cross-coupling.
- Suitable as internal standard for NMR, GC-MS, and LC-MS method development.
Medchemexpress LLC 1H-pyrazole-1-carboximidamide hydrochloride | 4023-02-3 | MFCD00210087 | 98.8% | 146.58 g/mol | C4H7ClN4 | 100 G
1H-pyrazole-1-carboximidamide hydrochloride is an organic biochemical reagent used as a building block and assay reagent in life-science research. Supplied as the hydrochloride salt, it is used in organic synthesis, analytical standards, and assay development.
- High purity suitable for research applications.
- Molecular weight 146.58 g/mol.
- CAS number 4023-02-3.
- Available in 25 g and 100 g pack sizes.
- Useful as a synthetic intermediate and analytical reference standard.
Medchemexpress LLC Phthalazinone pyrazole | 880487-62-7 | MFCD28399120 | 98.0% | 317.34 | C18H15N5O | 10MG
Phthalazinone pyrazole is a potent, selective, orally active small-molecule inhibitor of Aurora-A kinase used for research in cell biology and oncology. It has a biochemical IC50 of 0.031 μM against Aurora-A and shows cellular activity in multiple cancer cell lines.
- Potent Aurora-A kinase inhibition (IC50 0.031 μM).
- Demonstrated cellular activity in COLO 205, HCT-116, and MCF7 cell lines.
- High purity suitable for research (98.0%).
- Well-characterized physicochemical properties (C18H15N5O; MW 317.34).
- Available as solid and solution formats for assay flexibility.
- Supplied with a datasheet containing analytical and handling information.
eMolecules 25016-11-9 | 1-Methyl-1H-pyrazole-4-carboxaldehyde | Apollo Scientific | MFCD00460465 | 110.116 | C5H6N2O | 95.000 | Cn1cc(C=O)cn1 | 1g | 600854698
1-Methyl-1H-pyrazole-4-carboxaldehyde | Apollo Scientific | 25016-11-9 | MFCD00460465 | 110.116 | C5H6N2O | 95.000 | Cn1cc(C=O)cn1 | 1g | 600854698
eMolecules 25016-11-9 | 1-METHYL-1H-PYRAZOLE-4-CARBALDEHYDE | AstaTech | MFCD00460465 | 110.116 | C5H6N2O | 95.000 | Cn1cc(C=O)cn1 | 1g | 213336749
1-METHYL-1H-PYRAZOLE-4-CARBALDEHYDE | AstaTech | 25016-11-9 | MFCD00460465 | 110.116 | C5H6N2O | 95.000 | Cn1cc(C=O)cn1 | 1g | 213336749
![eMolecules 288246-16-2 | 4-Bromo-1h-pyrazole-3-carbonitrile | Combi-Blocks | MFCD00105683 | 171.985 | C4H2BrN3 | 98.000 | Brc1c[nH]nc1C#N | 1g | 117561221](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000216502.jpg-250.jpg)
eMolecules 288246-16-2 | 4-Bromo-1h-pyrazole-3-carbonitrile | Combi-Blocks | MFCD00105683 | 171.985 | C4H2BrN3 | 98.000 | Brc1c[nH]nc1C#N | 1g | 117561221
4-Bromo-1h-pyrazole-3-carbonitrile | Combi-Blocks | 288246-16-2 | MFCD00105683 | 171.985 | C4H2BrN3 | 98.000 | Brc1c[nH]nc1C#N | 1g | 117561221
![eMolecules 35344-95-7 | 1H-Pyrazole-4-carbaldehyde | Chem-Impex | MFCD02179514 | 96.089 | C4H4N2O | 95.000 | O=Cc1cn[nH]c1 | 1g | 112751114](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000216963.jpg-250.jpg)
eMolecules 35344-95-7 | 1H-Pyrazole-4-carbaldehyde | Chem-Impex | MFCD02179514 | 96.089 | C4H4N2O | 95.000 | O=Cc1cn[nH]c1 | 1g | 112751114
1H-Pyrazole-4-carbaldehyde | Chem-Impex | 35344-95-7 | MFCD02179514 | 96.089 | C4H4N2O | 95.000 | O=Cc1cn[nH]c1 | 1g | 112751114
Medchemexpress LLC RORC Human His SU 50ug | 50ug
RORC Protein Human (His SUMO) is the recombinant human-derived RORC expressed by E coli with N-6 His N-SUMO labeled tag
Medchemexpress LLC DIM-C-pPhOCH3 | 33985-68-1 | 99.4% | 352.43 | 25 MG
DIM-C-pPhOCH3 is a Nur77 agonist. Nur77 (Nerve growth factor-induced Bα, NGFI-Bα) is an orphan nuclear receptor. It is used for research purposes only. In vitro, DIM-C-pPhOCH3 decreases survival and induces apoptosis in RKO colon cancer cells, accompanied by the induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein. It also induces Nur77-independent apoptosis. In vivo, DIM-C-pPhOCH3 inhibits tumor growth in athymic nude mice bearing RKO cell xenografts.
- Nur77 agonist
- Induces apoptosis in RKO colon cancer cells
- Inhibits tumor growth in athymic nude mice bearing RKO cell xenografts
- Suitable for research applications
Medchemexpress LLC 1,3,5-Trimethylpyrazole | 1072-91-9 | MFCD00015536 | 500 MG
1,3,5-Trimethylpyrazole is a compound primarily used for chemical synthesis.
- High purity of 99.91%
- Molecular weight of 110.16
- Chemical formula C6H10N2
- Appearance as a solid below 38°C and liquid above 41°C
- Colorless to off-white appearance
- Soluble in DMSO and H2O at 100 mg/mL, requiring ultrasonic for dissolution
- Multiple in vivo dissolution protocols available, including those with DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil
- Long-term storage recommendations: -20°C for 3 years, 4°C for 2 years for pure form; -80°C for 6 months, -20°C for 1 month for in solvent