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Filtered Search Results
Chem-Impex International, Inc. 1-(2-Amino-4-methyl-1,3-thiazol-5-yl)ethanone | MFCD00051952 | 25G
1-(2-Amino-4-methyl-1,3-thiazol-5-yl)ethanone, MFCD00051952, 25G
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WELLINGTON LABORATORIES LLC 2 2 3 4 4 5 6 HEPTA DIPH
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NC2876334 2 2 3 4 4 5 6 HEPTA DIPH
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AARON CHEMICALS LLC 245 TRIMETHYL HYDROCHL 250MG
NC3844511 245 TRIMETHYL HYDROCHL 250MG
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ACROTEIN CHEMBIO INC
NC3902642 N-FMOC-N-METHYL-/S\-2-AMIN-25G
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Medchemexpress LLC Th-z145 | 2260887-57-6 | 97.1% | 394.34 g/mol | C16H28O7P2 | 10 MG
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TH-Z145 is a lipophilic bisphosphonate research compound that inhibits farnesyl pyrophosphate synthase (FPPS) with a reported IC50 of 210 nM. The compound is characterized by defined physicochemical properties (CAS 2260887-57-6; formula C16H28O7P2; mol wt 394.34 g/mol) and is supplied for research use in small milligram quantities, typically as a DMSO-soluble solid.
- Inhibits farnesyl pyrophosphate synthase with reported IC50 of 210 nM.
- Lipophilic bisphosphonate scaffold suitable for biochemical assays.
- High purity suitable for research applications.
- Supplied in small milligram packages for screening and synthesis.
- Soluble in DMSO for convenient stock preparation.
- Includes datasheet and analytical information for verification.
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eMolecules Ethyl 2-chloro-5-methylthiazole-4-carboxylate | 907545-27-1 | MFCD19443895 | 25g
Combi-Blocks | Ethyl 2-chloro-5-methylthiazole-4-carboxylate | 25g | 401040300 | QB-9241 | 98.000 | 907545-27-1 | MFCD19443895 | 205.660 | C7H8ClNO2S
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Medchemexpress LLC Macitentan (n-butyl analogue) | 556797-16-1 | MFCD28900696 | 99.4% | C20H21Br2N5O4S | 10MG
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Macitentan (n-butyl analogue) is an n-butyl analogue of macitentan that acts as a dual endothelin ETA and ETB receptor antagonist. It is intended for research use in in vitro and preclinical pharmacology studies focused on endothelin signaling. Not for human or veterinary use.
- Dual endothelin ETA and ETB receptor antagonist.
- High purity (99.35%).
- Molecular formula C20H21Br2N5O4S.
- Soluble in DMSO; available as 10 mM solutions.
- Available in small research pack sizes for screening.
- Suitable for in vitro and preclinical pharmacology studies.
- Provided as solid and solution formats for flexible use.
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Medchemexpress LLC tert-Butyl (3-aminopropyl)carbamate | 75178-96-0 | 99.82% | 174.24 | 100 G
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tert-Butyl (3-aminopropyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Biochemical reagent
- Can be used as a biological material or organic compound for life science related research
- N-Boc-1,3-propanediamine plays a key role in the synthesis of spermidine analogues and the suzuki reaction.
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Medchemexpress LLC 3-Chloro-N-(4-hydroxy-2-oxo-2H-chromen-3-yl)benzamide | 94205-22-8 | C16H10ClNO4 | 25 MG
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Anticancer agent 93 is a 4-Hydroxycoumarin derivative. It can inhibit invasion and migration of lung cancer cells by modulating the expression of epithelial-mesenchymal transition (EMT) effectors.
- 4-Hydroxycoumarin derivative
- Inhibits invasion and migration of lung cancer cells
- Modulates expression of epithelial-mesenchymal transition (EMT) effectors
- Purity of 98.01%
- White to off-white solid appearance
- Inhibits A549 cell invasion by approximately 50% at concentrations of 5-15 μM for 24 hours
- Significantly inhibits A549 cell migration at 15 μM for 24-72 hours
- Inhibits lung cancer cell motility by downregulating EMT markers at 5-15 μM for 4 hours
- Decreases expression of N-cadherin and E-cadherin in A549 cells
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BIOHIPPO AAV-TH-hM4D(Gi)-mCherry-WPRE-hGH-polyA
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Recombinant adeno associated virus expressing hM4D(Gi) fused to mCherry under the TH promoter with WPRE and hGH polyA elements. The Dre dependent configuration enables expression only after recombination, providing precise chemogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Medchemexpress LLC TERT activator-1 | 666699-46-3 | 99.5% | 331.77 | 50 MG
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TERT activator-1 is a small molecule activator of telomerase reverse transcriptase (TERT). It promotes TERT transcription through the MEK/ERK/AP-1 signaling cascade. It offers several benefits:
- Promotes adult neurogenesis.
- Enhances neuromuscular function.
- Reduces cellular senescence and systemic inflammation in aged mice.
- Can be used in the study of aging.
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Medchemexpress LLC Di(adamantan-1-yl)phosphine | 131211-27-3 | 97.0% | 302.43 | 5 G
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Di(adamantan-1-yl)phosphine is a biological molecule intended for research use only and not sold to patients. It appears as a white to off-white solid.
- Store at 4°C, protected from light, and under nitrogen
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light and under nitrogen
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Medchemexpress LLC 3-Chloro-N-(4-hydroxy-2-oxo-2H-chromen-3-yl)benzamide | 94205-22-8 | C16H10ClNO4 | 100 MG
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Anticancer agent 93 is a 4-Hydroxycoumarin derivative that demonstrates efficacy against lung cancer cells. It inhibits invasion and migration by modulating epithelial-mesenchymal transition (EMT) effectors, making it a potential candidate for cancer research.
- Inhibits A549 cell invasion by approximately 50%
- Significantly inhibits A549 cell migration
- Decreases lung cancer cell motility by downregulating EMT markers
- Reduces expression of N-cadherin and E-cadherin in A549 cells
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Medchemexpress LLC 2 4-Dimethylthiazole | 10G
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2 4-Dimethylthiazole | 10G
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Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 g·mol⁻¹ | C24H16ClN3O2S | 25 MG
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PNR-7-02 is a small-molecule inhibitor of DNA polymerase eta (Pol η) used in research on translesion synthesis and polymerase-mediated drug resistance. It is an indole thio-barbituric acid derivative reported to inhibit Pol η (IC50 ≈ 8 μM) and to act synergistically with cisplatin in cancer cell lines.
- Inhibits Pol η with reported IC50 ≈ 8 μM
- Also shows activity against hRev1 and hpol λ
- High purity (98.0%) suitable for biochemical assays
- Available as a 25 MG package, other sizes available
- Indole thio-barbituric acid scaffold, useful as a small-molecule probe
- For research use only; not for human or clinical use
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