Alpha beta-unsaturated carbonyl compounds
Biotium Reactive Dyes Biotin Cell Viability and Apoptosis Cellular Stains ViaTag 540 565 1/EA
ViaTag 540/565 Haloalkane Ligand is a bright fluorescent ligand for the HaloTag self-labeling protein tag Red fluorescent ViaTag 540/565 is cell permeant and has an excitation/emission of 543/572 nm 30 uL of 1000X
Medchemexpress LLC SP-141 | 1253491-42-7 | 98.9% | 324.38 | 50 MG
SP-141 is a specific inhibitor of MDM2 that promotes MDM2 auto-ubiquitination and degradation. It is used for research on pancreatic and breast cancer cells, inhibiting human pancreatic cancer cell growth in a p53-independent manner and showing selective cytotoxicity for cancer cells.
- Promotes MDM2 auto-ubiquitination and degradation.
- Inhibits human pancreatic cancer cell growth.
- Shows selective cytotoxicity for cancer cells.
- Suppresses pancreatic tumor growth in xenograft and orthotopic mouse models.
Medchemexpress LLC SP-141 | 1253491-42-7 | 98.9% | 324.38 | 25 MG
SP-141 is a specific inhibitor of MDM2. It promotes MDM2 auto-ubiquitination and degradation. This compound may be used for the research of pancreatic cancer and breast cancer cells.
- Specific inhibitor of MDM2.
- Promotes MDM2 auto-ubiquitination and degradation.
- Potential for research in pancreatic cancer and breast cancer cells.
- Inhibits human pancreatic cancer cell growth with IC50 values of less than 0.5 μM in a p53-independent manner.
- Shows selective cytotoxicity for cancer cells.
- Induces MDM2 auto-ubiquitination and proteasomal degradation.
- Suppresses pancreatic tumor growth in both xenograft and orthotopic mouse models.
- Reduced tumor volume by 75% in a pancreatic xenograft model without significant differences in body weight in one study.
Medchemexpress LLC IBSP Human His-SUM 100ug
The IBSP protein has a strong affinity for hydroxyapatite and plays a crucial role in mineralized matrix formation indicating its overall nature in this regard Its tight binding suggests an important role in cell-matrix interactions particularly in promoting RGD-dependent cell attachment IBSP Protein Human (His-SUMO) is the recombinant human-derived IBSP protein expressed by E coli with N-6 His N-SUMO labeled tag
Medchemexpress LLC IBSP Human His-SUM 20ug
The IBSP protein has a strong affinity for hydroxyapatite and plays a crucial role in mineralized matrix formation indicating its overall nature in this regard Its tight binding suggests an important role in cell-matrix interactions particularly in promoting RGD-dependent cell attachment IBSP Protein Human (His-SUMO) is the recombinant human-derived IBSP protein expressed by E coli with N-6 His N-SUMO labeled tag
Medchemexpress LLC IBSP Human His-SUM 50ug
The IBSP protein has a strong affinity for hydroxyapatite and plays a crucial role in mineralized matrix formation indicating its overall nature in this regard Its tight binding suggests an important role in cell-matrix interactions particularly in promoting RGD-dependent cell attachment IBSP Protein Human (His-SUMO) is the recombinant human-derived IBSP protein expressed by E coli with N-6 His N-SUMO labeled tag
Medchemexpress LLC Beta-ionone | 14901-07-6 | MFCD00078759 | 99.9% | 192.30 g/mol | C13H20O | 100 MG
β-Ionone is a small organic compound (C13H20O, MW 192.30 g/mol) used in research as an apoptosis inducer with reported anti-cancer activity in gastric adenocarcinoma SGC7901 cells. It is supplied as solid and solution formats for in vitro and in vivo studies and includes solubility and storage recommendations for reliable handling.
- High purity (≈99.85%).
- Available as solid and DMSO solution formats for experimental use.
- Soluble in DMSO and ethanol; insoluble in water.
- Storage recommendations for pure form and for solutions to preserve stability.
- Acts as an apoptosis inducer in cell studies.
- Molecular formula C13H20O; molecular weight 192.30 g/mol.
Medchemexpress LLC NG-497 | 2598242-66-9 | 99.1% | 315.36 | 25 MG
NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor. It targets the enzymatically active patatin-like domain of human ATGL and has potential value for tumor research. This product is for research use only.
- Selectively inactivates human and nonhuman primate ATGL.
- Abolishes human adipocytes in a dose-dependent and reversible manner lipolysis.
- Reduces lipolysis-dependent respiration in HepG2 cells.
- Does not impair mitochondrial function through off-target effects.
Medchemexpress LLC NG-497 | 2598242-66-9 | 99.1% | 315.36 | 5 MG
NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. It has potential value for tumor research. This product is for research use only.
- Selectively inactivates human and nonhuman primate ATGL.
- Does not inactivate structurally and functionally related lipid hydrolases.
- Abolishes human adipocytes in a dose-dependent and reversible manner of lipolysis.
- Reduces lipolysis-dependent respiration in HepG2 cells.
- Does not impair mitochondrial function through off-target effects.
Apexbio Technology LLC LIT-927-10MG
LIT-927 (CAS No 2172879-52-4) is a cutting-edge compound primarily researched in the field of pharmacology and biomedical sciences Originating from advanced drug development programs it functions through modulation of specific biological pathways acting on targeted receptors to alter cellular responses In vitro studies have demonstrated its potent activity within the nanomolar to low micromolar range highlighting its efficacy in modulating cellular functions This compound is commonly applied in a variety of research settings including cell models and animal studies and plays a crucial role in drug screening processes Experimental concentrations typically depend on the specific research design and objectives allowing for tailored use in diverse experimental scenarios
Apexbio Technology LLC LIT-927-100MG
LIT-927 (CAS No 2172879-52-4) is a cutting-edge compound primarily researched in the field of pharmacology and biomedical sciences Originating from advanced drug development programs it functions through modulation of specific biological pathways acting on targeted receptors to alter cellular responses In vitro studies have demonstrated its potent activity within the nanomolar to low micromolar range highlighting its efficacy in modulating cellular functions This compound is commonly applied in a variety of research settings including cell models and animal studies and plays a crucial role in drug screening processes Experimental concentrations typically depend on the specific research design and objectives allowing for tailored use in diverse experimental scenarios
Apexbio Technology LLC LIT-927-50MG
LIT-927 (CAS No 2172879-52-4) is a cutting-edge compound primarily researched in the field of pharmacology and biomedical sciences Originating from advanced drug development programs it functions through modulation of specific biological pathways acting on targeted receptors to alter cellular responses In vitro studies have demonstrated its potent activity within the nanomolar to low micromolar range highlighting its efficacy in modulating cellular functions This compound is commonly applied in a variety of research settings including cell models and animal studies and plays a crucial role in drug screening processes Experimental concentrations typically depend on the specific research design and objectives allowing for tailored use in diverse experimental scenarios
Apexbio Technology LLC LIT-927-5MG
LIT-927 (CAS No 2172879-52-4) is a cutting-edge compound primarily researched in the field of pharmacology and biomedical sciences Originating from advanced drug development programs it functions through modulation of specific biological pathways acting on targeted receptors to alter cellular responses In vitro studies have demonstrated its potent activity within the nanomolar to low micromolar range highlighting its efficacy in modulating cellular functions This compound is commonly applied in a variety of research settings including cell models and animal studies and plays a crucial role in drug screening processes Experimental concentrations typically depend on the specific research design and objectives allowing for tailored use in diverse experimental scenarios
Apexbio Technology LLC LIT-927-25MG
LIT-927 (CAS No 2172879-52-4) is a cutting-edge compound primarily researched in the field of pharmacology and biomedical sciences Originating from advanced drug development programs it functions through modulation of specific biological pathways acting on targeted receptors to alter cellular responses In vitro studies have demonstrated its potent activity within the nanomolar to low micromolar range highlighting its efficacy in modulating cellular functions This compound is commonly applied in a variety of research settings including cell models and animal studies and plays a crucial role in drug screening processes Experimental concentrations typically depend on the specific research design and objectives allowing for tailored use in diverse experimental scenarios
Medchemexpress LLC NG-497 | 2598242-66-9 | 99.07% | 315.36 | 1 ML
NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. It has potential value for tumor research. NG-497 selectively inactivates human and nonhuman primate ATGL but not structurally and functionally related lipid hydrolases, and abolishes human adipocytes in a dose-dependent and reversible manner lipolysis. NG-497 (40 μM, 80 min) reduces lipolysis-dependent respiration in HepG2 cells without impairing mitochondrial function through off-target effects.
- Selective human ATGL inhibitor
- Targets enzymatically active patatin-like domain
- Potential for tumor research
- Selectively inactivates human and nonhuman primate ATGL
- Abolishes human adipocytes in a dose-dependent and reversible manner lipolysis
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