This product is the TFA salt form of the compound M40. It functions as either an antagonist or a weak agonist for the galanin receptor, with its specific action depending on the particular subtype of galanin receptor present in different brain regions, including the hypothalamus, hippocampus, amygdala, and pancreas.
- Exhibits antagonist efficacy against galanin on memory tasks in models.
- Demonstrates potency in alleviating cognitive deficits associated with Alzheimer's disease.
- Blocks central cardiovascular responses induced by specific galanin fragments.
- Reduced vasopressor response and heart rate induced by galanin-(1-15).
- Blocks impairment in choice accuracy in animal models.