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Pre-packed columns, cartridges, and guard columns for separation of biomolecules and organic/inorganic analytes; includes normal/reversed phase HPLC, UHPLC, LC-MS, HILIC, mixed-mode, ion exchange, ligand exchange, and affinity column formats.
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YMC-Pack PVA-Sil is prepared from a 5 m 120 silica support which is bonded with a monomolecular polymer coating of vinyl alcohol The polymerized PVA completely covers both external and internal surfaces of the silica support protecting it against aggressive high pH buffers and solvents
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YMC s CHIRAL ART series features polysaccharide-derived chiral stationary phases (CSPs) based on amylose and cellulose tris-carbamate derivatives available in both coated and immobilized formats These columns provide exceptional stereoselectivity durability and solvent versatility supporting normal-phase reversed-phase and supercritical fluid chromatography (SFC) modes
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YMC-Pack C4 is ideal for analyzing mixtures with a wide range of component polarity This is due to the C4 bonded phase exhibiting shorter analysis time while still maintaining high resolution when compared to longer-chain bonded chemistries YMC-Pack C4 (Butyl) columns are available with three pore sizes to accommodate optimum separations of virtually any molecular-weight compound The 120 phase is used extensively with non-polar peptides which are too strongly retained on C8 and C18 The 200 and 300 phase columns effectively resolve many classes of proteins and biopolymers The wide pore butyl chemistry allows minimal distortion of tertiary conformation for large biomolecules and results in samples that are pure concentrated and high in biological activity
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Hydrosphere C18 is based on highly inert ultra-pure pH neutral silica and is designed to maintain a hydrophilic surface for superior separation of hydrophilic compounds Minimal metal content and very low concentrations of residual silanols make this an ideal phase for the analysis of basic pharmaceuticals and chelating compounds even under LC-MS conditions such as separation in non-phosphate buffered systems In addition the ability to separate polar compounds under highly aqueous mobile phase conditions without loss in retention plate counts and peak performance greatly enhances the versatility of Hydrosphere C18
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YMC s CHIRAL ART series features polysaccharide-derived chiral stationary phases (CSPs) based on amylose and cellulose tris-carbamate derivatives available in both coated and immobilized formats These columns provide exceptional stereoselectivity durability and solvent versatility supporting normal-phase reversed-phase and supercritical fluid chromatography (SFC) modes
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YMC-Pack C4 is ideal for analyzing mixtures with a wide range of component polarity This is due to the C4 bonded phase exhibiting shorter analysis time while still maintaining high resolution when compared to longer-chain bonded chemistries YMC-Pack C4 (Butyl) columns are available with three pore sizes to accommodate optimum separations of virtually any molecular-weight compound The 120 phase is used extensively with non-polar peptides which are too strongly retained on C8 and C18 The 200 and 300 phase columns effectively resolve many classes of proteins and biopolymers
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The high-purity silica found in YMC-Pack SIL columns provides virtually complete sample recovery The absence of silica impurities reduces non-specific sample adsorption and the totally porous nature of the silica provides high sample loading The elevated chemical purity of YMC silica results in a particle structure exhibiting high mechanical strength YMC-Pack SIL is suitable for separation of fat-soluble compounds using non-polar mobile phases as well as the separation of positional isomers that are difficult to separate in reversed-phase mode SIL-06 (60 pore size) has greater adsorption properties than SIL (120 pore size) due to its larger surface area and is generally useful for separating natural products with low molecular weight
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YMC-Pack C4 is ideal for analyzing mixtures with a wide range of component polarity This is due to the C4 bonded phase exhibiting shorter analysis time while still maintaining high resolution when compared to longer-chain bonded chemistries YMC-Pack C4 (Butyl) columns are available with three pore sizes to accommodate optimum separations of virtually any molecular-weight compound The 120 phase is used extensively with non-polar peptides which are too strongly retained on C8 and C18 The 200 and 300 phase columns effectively resolve many classes of proteins and biopolymers
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YMC-Pack C4 is ideal for analyzing mixtures with a wide range of component polarity This is due to the C4 bonded phase exhibiting shorter analysis time while still maintaining high resolution when compared to longer-chain bonded chemistries YMC-Pack C4 (Butyl) columns are available with three pore sizes to accommodate optimum separations of virtually any molecular-weight compound The 120 phase is used extensively with non-polar peptides which are too strongly retained on C8 and C18 The 200 and 300 phase columns effectively resolve many classes of proteins and biopolymers
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YMC-Pack ODS-AQ is a unique reversed-phase material with both a hydrophobic high carbon loading and a relatively hydrophilic surface Because of the hydrophilic surface ODS-AQ can be wetted with polar eluents It provides chromatographers reproducible retention and excellent peak shape in highly aqueous mobile phases including 100% water This is due to the C18 ligands on ODS-AQ actually being lifted from the surface by the action of the eluents penetrating the silica pores Selectivity on YMC-Pack ODS-AQ can be subtly different from that seen on conventional ODS columns Differences in selectivity are most often encountered when analyzing mixtures of relatively polar compounds Typically longer retention and greater resolution are observed with ODS-AQ Available in both 120 and 200 pore sizes YMC-Pack ODS-AQ is well-suited for analysis and purification of peptides and other biomolecules
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YMC-Pack ODS-A is a high-coverage fully-endcapped C18 phase which exhibits exceptional lot-to-lot reproducibility It is available in three different pore sizes and is suitable for the separation of a wide range of compounds YMC-Pack ODS-A in 120 pore size is used for high performance reversed phase separations It has selectivity for the separation of many organic compounds found in pharmaceutical chemical and biotechnology industries 200 ODS-A offers a unique mix of moderately large pores and high surface area for the analysis of compounds ranging from small organics and pharmaceuticals to moderately-sized proteins
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YMC-Pack ODS-A is a high-coverage fully-endcapped C18 phase which exhibits exceptional lot-to-lot reproducibility It is available in three different pore sizes and is suitable for the separation of a wide range of compounds YMC-Pack ODS-A in 120 pore size is used for high performance reversed phase separations It has selectivity for the separation of many organic compounds found in pharmaceutical chemical and biotechnology industries 200 ODS-A offers a unique mix of moderately large pores and high surface area for the analysis of compounds ranging from small organics and pharmaceuticals to moderately-sized proteins
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YMC-Pack ODS-AM is produced with specific emphasis on lot-to-lot reproducibility of the packing material Strict manufacturing control is performed on all aspects of quality including physical properties of the silica base gel as well as surface modifying processes ensuring exceptional reproducibility
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YMC-Triart phases are based on organic/inorganic hybrid particles that combine the high mechanical stability and efficiency of a silica-based packing material with the robust chemical stability of a polymer-based packing material This versatile resin is produced using tightly controlled particle formation technology adapted from micro-reactor technology The resulting uniform particle and pore size distributions as well as the smooth surface greatly contribute to excellent peak shape and separation reproducibility In addition YMC-Triart materials are highly resilient and robust when used at extreme pH elevated temperature and high pressure
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Phenyl columns provide unique selectivity when compared to aliphatic straight chain reversed phase materials such as C18 C8 and C4 YMC-Pack Phenyl is a monomerically-bonded phenyl and is fully endcapped Typical applications include aromatic compounds phenols fullerenes sweeteners
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