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MW 426.9 Da, Purity >99%. Selective CCR2 receptor antagonist (IC₅₀ values are 360 nM and 17.8 μM at CCR2 and CCR1 receptors, respectively). Inhibits MCP-1 and MCP-3 stimulated calcium influx (IC₅₀ values are 32 and 130 nM, respectively). Active in vivo.