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Filtered Search Results
Medchemexpress LLC 2'-Deoxy-5'-O-DMT-2'-fluorouridine | 146954-74-7 | 98.6% | 548.56 | 5 G
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2'-Deoxy-5'-O-DMT-2'-fluorouridine is a nucleoside analogue and a 5'-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity. It shows 100% inhibition against YFV at 20 mM and is noncytotoxic at concentrations up to 20 mM. This product is for research use only.
- Nucleoside analogue
- Potent anti-yellow fever (YFV) activity
- Shows 100% inhibition against YFV at 20 mM
- Noncytotoxic at concentrations up to 20 mM
- Solid appearance, off-white to light yellow in color
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Medchemexpress LLC 2'-Deoxy-2'-fluoro-β-D-arabinocytidine | 56632-83-8 | MFCD07374399 | >97.0% | 245.21 g·mol⁻1 | C9H12FN3O4 | 25 MG
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2'-Deoxy-2'-fluoro-β-D-arabinocytidine is a fluorinated nucleoside analogue used in biochemical and preclinical research. It functions as a modified cytidine analogue for studies of DNA synthesis inhibition, nucleic acid chemistry, and investigations of anticancer or antiviral activity. The compound is supplied as a solid for laboratory use and is documented with CAS and molecular formula identifiers.
- Fluorinated cytidine analogue for studies of DNA synthesis and metabolism.
- Applicable to cellular and biochemical assays investigating antitumor and antiviral effects.
- Suitable for milligram-scale laboratory use as a solid reagent.
- Serves as a building block in oligonucleotide and nucleic acid chemistry research.
- Documented by CAS and molecular formula for compound traceability.
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Medchemexpress LLC 15-deoxy-Δ-12,14-prostaglandin J2-d4 | 1542166-82-4 | 98.1% | 320.46 | 25 MG
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15-Deoxy-Δ-12,14-prostaglandin J2-d4 is the deuterium labeled 15-Deoxy-Δ-12,14-prostaglandin J2. 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. It is a selective PPARγ (EC50 of 2 μM) and a covalent PPARδ agonist, promoting efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) | 153666-19-4 | 99.9% | C9H16O9 | 25 MG
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3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) is a type of sialic acid that can be hydrolyzed by sialidase from the loach (Misgurnus fossilis).
- Solid appearance
- White to off-white color
- Soluble in water at 100 mg/mL (372.83 mM), requires ultrasonic
- Purity of 99.9%
- Molecular weight of 268.22
- Chemical formula: C9H16O9
- CAS number: 153666-19-4
- Ships at room temperature in continental US; may vary elsewhere
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
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Medchemexpress LLC 2'-Deoxy-2'-fluoroinosine | 80049-87-2 | C10H11FN4O4 | 250 MG
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2'-Deoxy-2'-fluoroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
- Broad antitumor activity targeting indolent lymphoid malignancies.
- Inhibits DNA synthesis.
- Induces apoptosis.
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Medchemexpress LLC 6-Azido-6-deoxy-D-glucose | 20847-05-6 | MFCD03265537 | 95.0% | 205.17 g/mol | C6H11N3O5 | 50 MG
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6-Azido-6-deoxy-D-glucose is an azide-functionalized glucose derivative used as a chemical reporter for metabolic labeling to visualize protein-specific glycosylation in living cells. Supplied as a powder with 95.0% purity, it is suitable for bioorthogonal click chemistry workflows and is stored under frozen conditions to preserve stability.
- Azide-functionalized glucose for metabolic labeling of glycoconjugates.
- Used to visualize protein-specific glycosylation in living cells.
- Provided as a powder with 95.0% purity.
- Molecular weight 205.17 g/mol; chemical formula C6H11N3O5.
- Store powder at -20°C; in solvent store at -80°C for up to 6 months.
- Suitable for azide-alkyne click chemistry tagging workflows.
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Medchemexpress LLC D-galactose, 6-azido-6-deoxy | 66927-03-5 | MFCD03265529 | 95.0% | 205.17 g·mol⁻1 | C6H11N3O5 | 25mg
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6-Azido-6-deoxy-D-galactose 95% can be used as a substrate in enzymology to study the activity and specificity of galactosyltransferases and other glycosylation enzymes
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Medchemexpress LLC 3′-deoxy-3′-fluoroguanosine | 123402-21-1 | MFCD09263707 | >98.0% | 285.23 g/mol | C10H12FN5O4 | 25 MG
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3′-Deoxy-3′-fluoroguanosine is a fluorinated guanosine nucleoside analogue used in biochemical and antiviral research. It is employed to study viral RNA synthesis and polymerase interactions and is supplied as a high-purity solid suitable for laboratory assays.
- Fluorinated guanosine nucleoside analogue
- Used to probe viral RNA synthesis and polymerase activity
- Molecular formula C10H12FN5O4
- Molecular weight 285.23 g/mol
- CAS number 123402-21-1
- Purity >98.0%
- Supplied as a solid (powder) for research use
- Also available as concentrated solution preparations for in vitro assays
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Cayman Chemical 2-deoxy-D-Glucose-13C6 1mg
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An internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS
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Medchemexpress LLC 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid sodium | 95.0% | C9H15NaO9 | 50 MG
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3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) sodium is a sialic acid. It protects the oligo/(poly)sialyl chains from exosialidases at the nonreducing terminal and plays a role in egg activation of salmonid fish. This compound is abundant in fetal cord red blood cells and malignant human ovarian cancer cells.
- Sialic acid
- Protects oligo/(poly)sialyl chains from exosialidases
- Plays a role in egg activation of salmonid fish
- Abundant in fetal cord red blood cells
- Abundant in malignant human ovarian cancer cells
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Medchemexpress LLC 2'-Deoxy-2'-fluoro-β-D-arabinocytidine | 56632-83-8 | 99.9% | 245.21 g/mol | C9H12FN3O4 | 1 ML
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2'-Deoxy-2'-fluoro-β-D-arabinocytidine is a fluorinated cytidine nucleoside analog provided for biochemical and cell-based research. It is supplied as solid material or as a ready-to-use 10 mM solution in DMSO, and is characterized by a molecular weight of 245.21 g/mol, CAS 56632-83-8, and high reported purity.
- Ready-to-use 10 mM solution in DMSO for rapid assay setup.
- Also available as solid in multiple mass sizes for custom preparation.
- High purity suitable for analytical and biological experiments.
- Fluorinated nucleoside analog useful for incorporation and enzymatic studies.
- Documentation provided: datasheet, certificate of analysis, and safety data sheet.
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Medchemexpress LLC 14-Deoxy-11,12-didehydroandrographolide | 42895-58-9 | 332.43 | 50 MG
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14-Deoxy-11,12-didehydroandrographolide is a noncytotoxic analogue of Andrographolide, primarily known for inhibiting NF-κB activation. This compound has demonstrated efficacy in a mouse asthma model, where it effectively reduces inflammatory cell recruitment, cytokine production (IL-4, IL-5, IL-13), serum IgE synthesis, pulmonary eosinophilia, mucus hypersecretion, mast cell degranulation, and airway hyper-responsiveness.
- Inhibits NF-κB activation
- Reduces inflammatory cell recruitment into bronchoalveolar lavage fluid
- Decreases IL-4, IL-5, IL-13, and eotaxin production
- Suppresses serum IgE synthesis
- Mitigates pulmonary eosinophilia and mucus hypersecretion
- Prevents mast cell degranulation
- Alleviates airway hyper-responsiveness in asthma models
- Reduces resistance and restores Cdyn in OVA-challenged mice
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Medchemexpress LLC 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil | 69123-94-0 | MFCD00870798 | 98.0% | 246.19 g·mol⁻1 | C9H11FN2O5 | 500 MG
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1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a fluorinated nucleoside analogue provided for research use. It exhibits reported antiviral activity and is characterized by defined physicochemical properties and batch-specific quality documentation for reliable use in in vitro and in vivo studies.
- Fluorinated nucleoside analogue with reported antiviral activity.
- Purity ≥98.0%.
- Chemical formula C9H11FN2O5; molecular weight 246.19 g·mol⁻1.
- White to off-white solid form, soluble in DMSO (100 mg/mL).
- Storage stability: powder -20°C (long-term) or 4°C (short-term); solutions -80°C for extended storage.
- Supplied with batch-specific certificate of analysis for quality verification.
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Medchemexpress LLC 3'-azido-3'-deoxy-5-methylcytidine | 1282040-14-5 | 99.9% | 282.26 g/mol | C10H14N6O4 | 5 MG
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3'-Azido-3'-deoxy-5-methylcytidine is an azide-functionalized nucleoside derivative used as an antiviral research reagent and a click-chemistry building block. The compound has reported inhibitory activity in cell-based antiviral assays and is suitable for copper-catalyzed and strain-promoted azide-alkyne cycloaddition bioconjugation.
- Azide-functionalized nucleoside for bioconjugation via CuAAC and SPAAC.
- Reported antiviral activity in cell-based assays, including XMRV and HIV-1 reverse transcriptase inhibition.
- Molecular formula C10H14N6O4 and molecular weight 282.26 g/mol.
- High purity (99.9%) suitable for research applications.
- Light yellow to yellow solid supplied in small-mass laboratory packs.
- Storage: powder at -20°C (long term) or 4°C; in solvent at -80°C or -20°C.
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Medchemexpress LLC 6A-azido-6A-deoxy-β-cyclodextrin | 98169-85-8 | MFCD05864973 | >85.0% | 1160.00 | C42H69N3O34 | 25 MG
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6A-azido-6A-deoxy-β-cyclodextrin is an azide-functionalized derivative of β-cyclodextrin used as a water-soluble click-chemistry reagent and bioconjugation building block. The azido group enables copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions for conjugation to alkyne-bearing molecules in chemical biology and drug-delivery research.
- Azide-functionalized for copper-catalyzed and strain-promoted azide-alkyne cycloaddition.
- Water-soluble β-cyclodextrin derivative for aqueous reactions.
- Suitable for bioconjugation and drug delivery research.
- Enables site-specific conjugation to alkyne-containing partners.
- Solid form, suitable for standard handling and storage.
- Compatible with common analytical methods such as HPLC and NMR.
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