Benzyl Derivatives
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4-Nitrobenzyl Chloride 98.0+%, TCI America™
CAS: 100-14-1 Molecular Formula: C7H6ClNO2 Molecular Weight (g/mol): 171.58 MDL Number: MFCD00007374 InChI Key: KGCNHWXDPDPSBV-UHFFFAOYSA-N Synonym: 4-nitrobenzyl chloride,1-chloromethyl-4-nitrobenzene,p-nitrobenzyl chloride,alpha-chloro-4-nitrotoluene,4-nitrobenzylchloride,benzene, 1-chloromethyl-4-nitro,alpha-chloro-p-nitrotoluene,p-chloromethyl nitrobenzene,4-chloromethyl nitrobenzene,unii-3bld9lvt3x PubChem CID: 7482 ChEBI: CHEBI:87406 IUPAC Name: 1-(chloromethyl)-4-nitrobenzene SMILES: C1=CC(=CC=C1CCl)[N+](=O)[O-]
| PubChem CID | 7482 |
|---|---|
| CAS | 100-14-1 |
| Molecular Weight (g/mol) | 171.58 |
| ChEBI | CHEBI:87406 |
| MDL Number | MFCD00007374 |
| SMILES | C1=CC(=CC=C1CCl)[N+](=O)[O-] |
| Synonym | 4-nitrobenzyl chloride,1-chloromethyl-4-nitrobenzene,p-nitrobenzyl chloride,alpha-chloro-4-nitrotoluene,4-nitrobenzylchloride,benzene, 1-chloromethyl-4-nitro,alpha-chloro-p-nitrotoluene,p-chloromethyl nitrobenzene,4-chloromethyl nitrobenzene,unii-3bld9lvt3x |
| IUPAC Name | 1-(chloromethyl)-4-nitrobenzene |
| InChI Key | KGCNHWXDPDPSBV-UHFFFAOYSA-N |
| Molecular Formula | C7H6ClNO2 |
1,2-Benzenedimethanol 98.0+%, TCI America™
CAS: 612-14-6 Molecular Formula: C8H10O2 Molecular Weight (g/mol): 138.17 MDL Number: MFCD00004626 InChI Key: XMUZQOKACOLCSS-UHFFFAOYSA-N Synonym: 1,2-benzenedimethanol,1,2-phenylenedimethanol,phthalyl alcohol,1,2-dihydroxymethylbenzene,o-xylene-alpha,alpha'-diol,2-hydroxymethyl phenyl methanol,benzenedimethanol,o-xylylene glycol,1,2-di hydroxymethyl benzene,2-hydroxymethylbenzenemethanol PubChem CID: 69153 IUPAC Name: [2-(hydroxymethyl)phenyl]methanol SMILES: OCC1=CC=CC=C1CO
| PubChem CID | 69153 |
|---|---|
| CAS | 612-14-6 |
| Molecular Weight (g/mol) | 138.17 |
| MDL Number | MFCD00004626 |
| SMILES | OCC1=CC=CC=C1CO |
| Synonym | 1,2-benzenedimethanol,1,2-phenylenedimethanol,phthalyl alcohol,1,2-dihydroxymethylbenzene,o-xylene-alpha,alpha'-diol,2-hydroxymethyl phenyl methanol,benzenedimethanol,o-xylylene glycol,1,2-di hydroxymethyl benzene,2-hydroxymethylbenzenemethanol |
| IUPAC Name | [2-(hydroxymethyl)phenyl]methanol |
| InChI Key | XMUZQOKACOLCSS-UHFFFAOYSA-N |
| Molecular Formula | C8H10O2 |
Medchemexpress LLC 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- | 957205-14-0 | 98.0% | C10H21BrO5 | 1 G
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Bromo-PEG5-alcohol is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. PROTACs work by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs utilize the ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- | 957205-14-0 | 98.0% | C10H21BrO5 | 250 MG
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Bromo-PEG5-alcohol is a PEG-based PROTAC linker, instrumental in the synthesis of PROTACs. These specialized molecules leverage the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins, offering a novel approach in therapeutic development.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs utilize the intracellular ubiquitin-proteasome system
- Designed for selective degradation of target proteins
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Medchemexpress LLC 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- | 957205-14-0 | 98.0% | C10H21BrO5 | 100 MG
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Bromo-PEG5-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are composed of two distinct ligands connected by a linker, where one targets an E3 ubiquitin ligase and the other targets a specific protein. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Utilizes the ubiquitin-proteasome system
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eMolecules Ambeed / 2-Bromomethylphenylboronic acid / 5g / 552536343 / A113992 / / 91983-14-1 / MFCD01318941 / 214.850 / C7H8BBrO2
Ambeed / 2-Bromomethylphenylboronic acid / 5g / 552536343 / A113992 / / 91983-14-1 / MFCD01318941 / 214.850 / C7H8BBrO2
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eMolecules Combi-Blocks 14-Dibromo-2-butanol 5g 267180652 QC-3815 95.000 19398-47-1 MFCD00000252 231.915 C4H8Br2O
Combi-Blocks 14-Dibromo-2-butanol 5g 267180652 QC-3815 95.000 19398-47-1 MFCD00000252 231.915 C4H8Br2O
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eMolecules Synthonix / 4-benzyl 1-(tert-butyl) 4-methylpiperidine-14-dicarboxylate / 250mg / 794075203 / AC80574 / / 296240-48-7 / MFCD11975548 / 333.428 / C19H27NO4
Synthonix / 4-benzyl 1-(tert-butyl) 4-methylpiperidine-14-dicarboxylate / 250mg / 794075203 / AC80574 / / 296240-48-7 / MFCD11975548 / 333.428 / C19H27NO4
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eMolecules Synthonix / benzyl 3-[(tert-butoxy)carbonyl]amino-4-hydroxypiperidine-1-carboxylate / 25mg / 779536718 / AC77820 / / 1418126-14-3 / MFCD22572927 / 350.415 / C18H26N2O5
Synthonix / benzyl 3-[(tert-butoxy)carbonyl]amino-4-hydroxypiperidine-1-carboxylate / 25mg / 779536718 / AC77820 / / 1418126-14-3 / MFCD22572927 / 350.415 / C18H26N2O5
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eMolecules AstaTech / 4-BENZYL 1-(TERT-BUTYL) (R)-2-(CYANOMETHYL)PIPERAZINE-14-DICARBOXYLATE / 0.25g / 648576253 / AT29637 / 95.000 / 2740593-26-2 / [null] / 359.426 / C19H25N3O4
AstaTech / 4-BENZYL 1-(TERT-BUTYL) (R)-2-(CYANOMETHYL)PIPERAZINE-14-DICARBOXYLATE / 0.25g / 648576253 / AT29637 / 95.000 / 2740593-26-2 / [null] / 359.426 / C19H25N3O4
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Sigma Aldrich 2,6-Dichlorobenzyl chloride
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
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| CAS | 2014-83-7 |
|---|
Apexbio Technology LLC Miconazole 22916-47-8 1g
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Miconazole (22916-47-8) is a small-molecule inhibitor targeting fungal cytochrome P450-dependent lanosterol 14 -demethylase It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal cell membrane integrity Miconazole exerts its biological activity primarily through selective binding and inhibition of lanosterol 14 -demethylase an enzyme essential for ergosterol formation In in vitro studies Miconazole demonstrates antifungal activity with reported IC50 values generally ranging from approximately 0 1 to 10 M depending on the fungal species and assay conditions Based on these pharmacological properties Miconazole holds research potential in studying fungal infections fungal lipid metabolism and membrane regulatory pathways as well as in exploring antibacterial applications related to cell membrane-associated metabolic targets
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Apexbio Technology LLC Miconazole Nitrate 22832-87-7 1g
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Miconazole Nitrate (CAS 22832-87-7) is a small-molecule inhibitor targeting lanosterol 14-alpha-demethylase It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal cell membrane integrity and function Miconazole Nitrate exerts its biological activity primarily through inhibition of the enzyme lanosterol 14-alpha-demethylase In in vitro studies Miconazole Nitrate demonstrates antifungal inhibitory activity with IC50 values ranging from approximately 0 1 to 10 M depending on specific fungal species and assay conditions Based on these pharmacological properties Miconazole Nitrate holds research potential in evaluating susceptibility profiles and resistance phenotypes of fungal and bacterial pathogens exploring pathogen-host interactions antimicrobial mechanisms of action and fungal metabolic pathways
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TARGETMOL CHEMICALS INC PP121 25MG
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Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PP-121 is a multi-targeted inhibitor of PDGFR (IC50 2 nM) Hck (IC50 8 nM) mTOR (IC50 10 nM) VEGFR2(IC50 12 nM) Src (IC50 14 nM) and Abl (IC50 18 nM) also inhibits DNA-PK (IC50 60 nM). purity: 99%
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