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Filtered Search Results
Biotium SOX9 / SRY-box 9(rSOX9/2288), CF647 conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and phot
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eMolecules 1857352-95-4 | Cy5.5 DBCO | Broadpharm1161.340 | C58H56N4O14S4 | 95.000 | CN1\C(=C\C=C\C=C\C2=[N+](CCCCCC(=O)NCCC(=O)N3Cc4ccccc4C#Cc4ccccc34)c3ccc4c(cc(cc4c3C2(C)C)S(O)(=O)=O)S([O-])(=O)=O)C(C)(C)c2c1ccc1c(cc(cc21)S(O)(=O)=O)S(O)(=O)=O | 1mg | 510428473
Cy5.5 DBCO | Broadpharm | 1857352-95-41161.340 | C58H56N4O14S4 | 95.000 | CN1\C(=C\C=C\C=C\C2=[N+](CCCCCC(=O)NCCC(=O)N3Cc4ccccc4C#Cc4ccccc34)c3ccc4c(cc(cc4c3C2(C)C)S(O)(=O)=O)S([O-])(=O)=O)C(C)(C)c2c1ccc1c(cc(cc21)S(O)(=O)=O)S(O)(=O)=O | 1mg | 510428473
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Cayman Chemical ZngIbrosIde R1 5mg
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A triterpene saponin and an active metabolite of ginsenoside Ro; cytotoxic to B16/F10 murine melanoma cells (IC50 = 24.52 UG/ml); inhibits tube formation by HUVECs at 40 UG/ml; reduces tumor growth in a B16/F10 murine melanoma model at 25 mg/kg
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BIOHIPPO AAV-TH-Cre-P2A-EGFP-WPREs
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Recombinant adeno associated virus expressing Cre fused to EGFP under the TH promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Cayman Chemical VHL LIgnd 1hydrochlorIde 100mg
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A PROTAC building block; VHL E3 binding portion of BET PROTAC MZ1
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BIOHIPPO AAV-ChAT-DIO-EGFP-WPREs
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Recombinant adeno associated virus expressing EGFP under the ChAT promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Medchemexpress LLC Recombinant human CEBPA protein (His-tag) | >95.0% | 10UG
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Recombinant human CEBPA is a His-tagged transcription factor produced in Escherichia coli and supplied lyophilized for research applications. The product is suitable for in vitro biochemical assays, antibody validation, and studies of transcriptional regulation.
- Recombinant human CEBPA protein with N-terminal His tag.
- Expressed in Escherichia coli and purified to >95.0% purity.
- Approximate molecular weight 44 kDa.
- Lyophilized formulation for long-term storage and convenient reconstitution.
- Available in small sizes such as 10 μg for micro-scale experiments.
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Biotium pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein)(TFF1/2133), CF647 conjugate, 0.1mg/mL
Recognizes a polypeptide of 6. 5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood o
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Cayman Chemical HIston H3CItrulInATd R26 250ug
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A biotinylated peptide fragment of histone H3
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ABclonal Technology GPC4 Rabbit pAb
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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3 end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.
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BIOHIPPO AAV-TH-Cre-WPRE-hGH-polyA
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Recombinant adeno associated virus expressing Cre under the TH promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Biotium pS2(TFF1/1091), CF740 conjugate, 0.1mg/mL
This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased
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Apexbio Technology LLC tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus] 5mg
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tumor protein p53 binding protein fragment is a protein fragment derived from Homo sapiens and Mus musculus that interacts with the central DNA-binding domain of tumor protein p53 It is designed to modulate p53-dependent transcriptional activation thereby influencing DNA damage response pathways tumor protein p53 binding protein fragment exerts its biological activity by participating in the cellular DNA damage response network particularly through ATM-dependent phosphorylation and localization to DNA damage foci following double-strand breaks Based on these properties tumor protein p53 binding protein fragment holds research potential in studying DNA damage signaling genomic stability and tumorigenesis mechanisms
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BIOHIPPO AAV-D2(ENK)-Cre-WPRE-bGH-polyA
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Recombinant adeno associated virus expressing Cre under the D2 (ENK) promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Medchemexpress LLC 5-FAM-Alkyne | 510758-19-7 | 95.0% | 50 MG
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5-FAM-Alkyne is a highly selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP). It functions as a click chemistry reagent, featuring an alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. The FAM fluorophore readily diffuses in solution, producing a strong fluorescence signal. This product is intended for research use only.
- Highly selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP)
- Functions as a click chemistry reagent
- Contains an alkyne group for click chemistry reactions
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- FAM fluorophore diffuses easily into solution
- Emits a strong fluorescence signal
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