Oligonucleotides
Meridian Life Science Gly-Free DNA Helicase -HC, 20UL
Glycerol-Free DNA Helicase (HC) Kit is a multi-domain enzyme with both ATPase and helicase activities. It unwinds double-stranded DNA with 3’ to 5’ with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Helicase works in coordination with an accessory protein, methyl-directed mismatch repair (MutL) protein that stimulates the helicase activity. Glycerol-Free DNA Helicase (HC) has been optimized to deliver excellent, stable performance without glycerol, allowing you to deliver reliable results with the added capability for lyophilization. This gives you the flexibility to confidently store mixtures at ambient temperature or produce diagnostic assays that rely on miniaturized reaction components, such as point-of-care assays.
BIOHIPPO AAV-CRH-Cre-P2A-EGFP-WPREs
Recombinant adeno associated virus expressing Cre fused to EGFP under the CRH promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Cayman Chemical 17R 18S-EpETE 50ug
An EPA metabolite and activator of KCa1.1/BK channels; increases the potassium current amplitude by 15-fold in isolated rat cerebral artery VSMCs at 50 nM; has negative chronotropic effects in NRCMs (EC50 = ~1-2 nM) and prevents calcium-induced increases in NRCM spontaneous beating
Cayman Chemical 5 Z 8 ZTetradecadIenoIc Ac
An internal standard for the quantification of 5(Z),8(Z)-tetradecadienoic acid by GC- or LC-MS
ABclonal Technology NCKAP1 Rabbit pAb
Contributes to small GTPase binding activity. Involved in Rac protein signal transduction, positive regulation of Arp2/3 complex-mediated actin nucleation, and positive regulation of lamellipodium assembly. Located in extracellular exosome and focal adhesion. Part of SCAR complex.
Miltenyi Biotec, Inc. CD43-PE-Vio770, human, DF-T1, 30 tests
Detection of human CD43+ cells.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
BIOHIPPO AAV-mscRE13-minBGpromoter-Cre-WPRE-hGH-polyA
Recombinant adeno associated virus expressing Cre under the mscRE13 promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Medchemexpress LLC 1H-Benzimidazole-5-carboxamide, 1-[(2E)-4-[5-(aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)ca... | 2138299-33-7 | 99.9% | 849.94 | 50 MG
diABZI STING agonist-1 tautomerism is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. It is a tautomerism of diABZI STING agonist-1.
- Selective stimulator of interferon genes (STING) receptor agonist
- EC50s of 130 nM for human and 186 nM for mouse
- Shows high selectivity against over 350 kinases tested at 1 μM
- Induces STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo
- Exhibits systemic exposure with a half-life of 1.4 h in vivo
- Results in significant tumor growth inhibition and improved survival in vivo
Biotium SOX9 / SRY-box 9(SOX9/3141R), Biotin conjugate, 0.1mg/mL
Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye col
Cayman Chemical TDG Thymine DNA glycosylase
A mixture of porcine ganglioside GT1b with primarily C180 fatty acyl chain lengths as well as a lower amount of C200 fatty acyl chain lengths among various others characterized by having two sialic residues linked to the inner galactose unit binds to the neurotoxins BTxA BTxA heavy chain and tetanus toxin (IC50s 11 0.74 and 7.2 M respectively) ganglioside GT1b-containing liposomes can bind to the major coat protein VP1 from MCPyV a putative MCPyV receptor decreases spontaneous production of IL-6 IL-10 IgG IgM and IgA in human PBMCs by 31.4 30.5 60 59.5 and 58 respectively at 10 M
Biotium CD43(84-3C1), CF740 conjugate, 0.1mg/mL
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 (Workshop III). 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended f
American Research Products Inc AMERICAN RESEARCH PRODUCTS INC
5000607316 MOUSE CHAT COLORSTEP ELISA KIT
ABclonal Technology GPC4 Rabbit pAb
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3 end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.
Cayman Chemical Reagent 1R1 8mL
Reagent 1 (R1) has been tested and formulated to work exclusively with Cayman’s Total and Direct Bilirubin Colorimetric Assay Kit (Item No. 701720).