Oligonucleotides
Cayman Chemical TDG Thymine DNA glycosylase
A mixture of porcine ganglioside GT1b with primarily C180 fatty acyl chain lengths as well as a lower amount of C200 fatty acyl chain lengths among various others characterized by having two sialic residues linked to the inner galactose unit binds to the neurotoxins BTxA BTxA heavy chain and tetanus toxin (IC50s 11 0.74 and 7.2 M respectively) ganglioside GT1b-containing liposomes can bind to the major coat protein VP1 from MCPyV a putative MCPyV receptor decreases spontaneous production of IL-6 IL-10 IgG IgM and IgA in human PBMCs by 31.4 30.5 60 59.5 and 58 respectively at 10 M
American Research Products Inc AMERICAN RESEARCH PRODUCTS INC
5000607316 MOUSE CHAT COLORSTEP ELISA KIT
ABclonal Technology GPC4 Rabbit pAb
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3 end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.
Biotium CD43 (T-Cell Marker) (SPN/1766R), CF647 conjugate, 0.1mg/mL
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundan
American Research Products Inc Human GRIN2B ELISA Kit
This Human Glutamate Receptor Ionotropic N-Methyl-D-Aspartate 2B (GRIN2B) ELISA Kit is a precoated Sandwich ELISA assay designed to detect and quantify the target analyte in tissue homogenates cell lysates and other biological fluids This product is for Research Use Only
Apexbio Technology LLC EZ Cap™ Cre mRNA (5-moUTP) 100ug (1mg/mL)
EZ Cap Cre mRNA 5-moUTP encodes Cre recombinase a tyrosine recombinase enzyme that facilitates homologous DNA recombination between two specific loxP recognition sites It is designed to promote precise DNA recombination thereby enabling conditional gene modification in mammalian systems EZ Cap Cre mRNA 5-moUTP exerts its biological activity primarily through expression of Cre recombinase which catalyzes site-specific recombination at loxP sites This mRNA incorporates a Cap 1 structure and 5-methoxyuridine triphosphate (5-moUTP) modification to reduce innate immune responses and improve translational stability Based on these properties EZ Cap Cre mRNA 5-moUTP holds research potential in genome editing experiments conditional gene knockout studies and reporter gene activation in mammalian research models
Biotium pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein)(TFF1/2133), 1mg/mL
Recognizes a polypeptide of 6. 5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood o
Biotium SOX9 / SRY-box 9(rSOX9/2288), CF647 conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and phot
Cayman Chemical ZngIbrosIde R1 5mg
A triterpene saponin and an active metabolite of ginsenoside Ro; cytotoxic to B16/F10 murine melanoma cells (IC50 = 24.52 UG/ml); inhibits tube formation by HUVECs at 40 UG/ml; reduces tumor growth in a B16/F10 murine melanoma model at 25 mg/kg
BIOHIPPO AAV-TH-Cre-P2A-EGFP-WPREs
Recombinant adeno associated virus expressing Cre fused to EGFP under the TH promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Cayman Chemical VHL LIgnd 1hydrochlorIde 100mg
A PROTAC building block; VHL E3 binding portion of BET PROTAC MZ1
BIOHIPPO AAV-ChAT-DIO-EGFP-WPREs
Recombinant adeno associated virus expressing EGFP under the ChAT promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Medchemexpress LLC Recombinant human CEBPA protein (His-tag) | >95.0% | 10UG
Recombinant human CEBPA is a His-tagged transcription factor produced in Escherichia coli and supplied lyophilized for research applications. The product is suitable for in vitro biochemical assays, antibody validation, and studies of transcriptional regulation.
- Recombinant human CEBPA protein with N-terminal His tag.
- Expressed in Escherichia coli and purified to >95.0% purity.
- Approximate molecular weight 44 kDa.
- Lyophilized formulation for long-term storage and convenient reconstitution.
- Available in small sizes such as 10 μg for micro-scale experiments.
Medchemexpress LLC 5-FAM-Alkyne | 510758-19-7 | 95.0% | 50 MG
5-FAM-Alkyne is a highly selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP). It functions as a click chemistry reagent, featuring an alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. The FAM fluorophore readily diffuses in solution, producing a strong fluorescence signal. This product is intended for research use only.
- Highly selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP)
- Functions as a click chemistry reagent
- Contains an alkyne group for click chemistry reactions
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- FAM fluorophore diffuses easily into solution
- Emits a strong fluorescence signal