Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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2,491 – 2,505 of 7,110 results

2,491

American Radiolabeled Chemicals Inc TOBRAMYCIN 3HG 50UC

Tobramycin-3H(G) 50uCi in ethanol, 1 mCi/ml, 200-250 mCi/mmol, M.W. 467.5, Shipped in Dry Ice, Exclusive

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2,492

Medchemexpress LLC Thz1 (hydrochloride) | 1604810-83-4 | MFCD28167785 | 99.1% | 602.51 g/mol | C31H29Cl2N7O2 | 10 MG

THZ1 (hydrochloride) is the hydrochloride salt of THZ1, a selective, covalent inhibitor of cyclin-dependent kinase 7 (CDK7) with low-nanomolar potency. It also inhibits CDK12 and CDK13 and is used in preclinical studies to probe transcriptional regulation, cell-cycle control, and oncology models.

Selective covalent CDK7 inhibitor (IC50 ~3.2 nM).
Hydrochloride salt form for improved handling.
Molecular formula C31H29Cl2N7O2; molecular weight 602.51 g/mol.
High purity (~99.06%) suitable for research applications.
Supplied in small research sizes, including 10 MG.
Certificate of analysis and safety data sheet available.
Common applications: transcriptional regulation, cell-cycle, and oncology research.

Pricing & Availability

2,493

Medchemexpress LLC HY-103708 10mg Medchemexpress, Nezukone CAS:13656-81-0 Purity:>98%

Medchemexpress, HY-103708 10mg Nezukone CAS:13656-81-0 Nezukone is a derivative of hinokitiol. Hinokitiol can restore iron transports, however, Nezukone cannot bind or transport iron. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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2,494

Medchemexpress LLC HY-100527 50mg Medchemexpress, AN2718 CAS:174672-06-1 Purity:>98%

Medchemexpress, HY-100527 50mg AN2718 CAS:174672-06-1 AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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2,495

Medchemexpress LLC (3S,4S)-PF-06459988 | 1858291-14-1 | 98.97% | 431.88 | 5 MG

(3S, 4S)-PF-06459988 is the S enantiomer of PF-06459988 with less activity.
It is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR).
Possesses excellent selectivity against EGFR wild-type.
Features a minimally reactive electrophile that reduces the propensity of off-target labeling.

Pricing & Availability

2,496

Medchemexpress LLC Azido-PEG4-Val-Cit-PAB-MMAE | 1869126-64-6 | 99.4% | 1396.71 g/mol | C69H113N13O17 | 1 MG

Azido-PEG4-Val-Cit-PAB-MMAE is an azide-functionalized PEG4 Val-Cit PAB linker-drug conjugate that couples a cleavable protease-sensitive Val-Cit dipeptide linker to the cytotoxic payload monomethyl auristatin E (MMAE). It is intended for research use in antibody-drug conjugate (ADC) synthesis and for click-chemistry conjugation (CuAAC or SPAAC).

Azide functional group for copper-catalyzed and strain-promoted click reactions.
Cleavable Val-Cit-PAB linker for protease-triggered payload release.
Includes MMAE payload for potent cytotoxic activity in ADC constructs.
High purity suitable for research applications.
Solid, white to off-white appearance; supplied in small research quantities.

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2,497

Medchemexpress LLC Kasugamycin hydrochloride | 19408-46-9 | 100.0% | 1 ML

Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes, but not to the 50s subunit, and exhibits anti-infective activity. It mimics mRNA nucleotides, disrupting tRNA binding and inhibiting canonical translation initiation. It increases the sensitivity of mycobacteria to Rifampicin in vitro and in mouse infection models.

Inhibits P-site tRNA binding by destabilizing mRNA.
Decreases the mistranslation rates of asparagine-to-aspartate and glutamine-to-glutamate.
Reduces mycobacterial rifampicin phenotypic resistance in wild-type and high mistranslating gatA mutant mycobacterial strains.
Results in dose-dependent concentration-time profiles in plasma with rapid clearance of M. tuberculosis in infected mice.
Increases Rifampicin susceptibility by 30-fold in mouse models.

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2,498

Medchemexpress LLC Hzx-02-059 (Compound 13) | 2240205-30-3 | 99.4% | 487.48 g·mol⁻¹ | C27H20F3N5O | 5 MG

HZX-02-059 is a small-molecule research compound that induces methuosis and functions as a dual PIKfyve/tubulin inhibitor with reported anticancer activity. It disrupts endocytosis-exocytosis balance to produce extensive intracellular vacuolization and promotes cell death pathways, including apoptosis; reported signaling effects include inhibition of PI3K/AKT phosphorylation and suppression of c-Myc and NF-κB transcription.

Induces methuosis and intracellular vacuolization.
Dual PIKfyve and tubulin inhibitory activity.
Promotes apoptosis and cell death in cellular models.
Modulates PI3K/AKT, c-Myc, and NF-κB signaling.
Supplied as a high-purity small molecule for cellular assays.
Molecular formula C27H20F3N5O; molecular weight 487.48 g·mol⁻¹.

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2,499

Medchemexpress LLC HY-12444 10mg Medchemexpress, Y15 CAS:4506-66-5 Purity:>98%

Medchemexpress, HY-12444 10mg Y15 CAS:4506-66-5 Y15 is a potent and specific inhibitor of focal adhesion kinase (FAK) that inhibits its autophosphorylation activity, decreases the viability of cancer cells, and blocks tumor growth. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Pricing & Availability

2,500

eMolecules 1010411-21-8 | 2-((tert-Butylamino)methyl)-5-((7-chloroquinolin-4-yl)amino)phenol dihydrochloride | MFCD16627991 | 50mg

Ambeed | 5-Chloro-2-(chloromethyl)pyridine | 250mg | 561134408 | A449428 | 10177-24-9 | MFCD10697588 | 162.010 | C6H5Cl2N

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2,501

Apexbio Technology LLC Neomycin sulfate(Synonyms: Neomycin sulphate, Fradiomycin sulfate, Neomycin trisulfate salt hydrate, Neosulf), 10g, CAS: 1405-10-3.

Neomycin sulfate (CAS 1405-10-3) is an aminoglycoside antibiotic that interacts with nucleic acid structures and ion channels influencing several biological processes It inhibits hammerhead ribozyme cleavage reactions by preferentially stabilizing the ribozyme-substrate ground-state complex thereby impeding catalytic turnover In HIV-1 research neomycin disrupts the interaction between Tat protein and the viral RNA TAR element via an allosteric noncompetitive mechanism Additionally neomycin binds specifically to DNA triplex structures particularly stabilizing TAT triplets It also demonstrates voltage- and concentration-dependent blockage of ryanodine receptor channels mainly from the luminal side These properties make neomycin sulfate valuable for mechanistic studies involving RNA/DNA structure interactions and channel functions

Pricing & Availability

2,502

Medchemexpress LLC Amoxicillin sodium | 34642-77-8 | 98.0% | 500 MG

Amoxicillin sodium is an antibiotic that exhibits good oral absorption and broad-spectrum antimicrobial activity. It functions by inhibiting the biosynthesis of polypeptides in the cell wall, which in turn inhibits cell growth.

Good oral absorption
Broad-spectrum antimicrobial activity
Inhibits the biosynthesis of polypeptides in the cell wall
Decreases living cells and increases the degree of cell wall rupture in a dose-dependent manner
Inhibits bacterial strain numbers and improves the survival rate in rats
Effective against infection with Chlamydia trachomatis in mice

Pricing & Availability

2,503

Medchemexpress LLC Thiamphenicol | 15318-45-3 | 99.6% | 1 ML

Thiamphenicol is a methyl-sulfonyl derivative of Chloramphenicol, acting as a broad-spectrum antimicrobial antibiotic. It inhibits protein synthesis and provides a bacteriostatic effect by binding to the 50S ribosomal subunit, making it effective against Gram-negative, Gram-positive aerobic, and anaerobic bacteria. Studies have indicated rapid absorption and high bioavailability (over 70%) after oral administration.

Inhibits protein synthesis
Bacteriostatic effect against Gram-negative, Gram-positive aerobic, and anaerobic bacteria
Significant post-antibiotic effect (PAE)
Potent bactericidal activity against H. influenzae
Good in vitro activity against multi-resistant pathogens
Rapid absorption and high bioavailability in vivo

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2,504

Apexbio Technology LLC Geldanamycin 30562-34-6 10mM (in 1mL DMSO)

Geldanamycin is an antibiotic from Streptomyces hygroscopicus that inhibits heat shock protein 90 (Hsp90) by binding to its ATP-binding pocket This disruption affects protein folding and stabilization impacting cell proliferation stress response and tumor biology Geldanamycin is used as a molecular tool in these studies and has activity against various microbes including bacteria fungi protozoa and nematodes IC50 values range from nanomolar to micromolar levels depending on the cell line and conditions It is also applied in research on vascular relaxation glucocorticoid receptor modulation and inflammation-related signaling pathways

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2,505

Medchemexpress LLC HY-103364A 5mg Medchemexpress, C-021 (dihydrochloride) CAS:1784252-84-1 Purity:>98%

Medchemexpress, HY-103364A 5mg C-021 (diHCl) CAS:1784252-84-1 C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Antibiotics

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American Radiolabeled Chemicals Inc TOBRAMYCIN 3HG 50UC Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Thz1 (hydrochloride) | 1604810-83-4 | MFCD28167785 | 99.1% | 602.51 g/mol | C31H29Cl2N7O2 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-103708 10mg Medchemexpress, Nezukone CAS:13656-81-0 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-100527 50mg Medchemexpress, AN2718 CAS:174672-06-1 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (3S,4S)-PF-06459988 | 1858291-14-1 | 98.97% | 431.88 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Azido-PEG4-Val-Cit-PAB-MMAE | 1869126-64-6 | 99.4% | 1396.71 g/mol | C69H113N13O17 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Kasugamycin hydrochloride | 19408-46-9 | 100.0% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Hzx-02-059 (Compound 13) | 2240205-30-3 | 99.4% | 487.48 g·mol⁻¹ | C27H20F3N5O | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-12444 10mg Medchemexpress, Y15 CAS:4506-66-5 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Neomycin sulfate(Synonyms: Neomycin sulphate, Fradiomycin sulfate, Neomycin trisulfate salt hydrate, Neosulf), 10g, CAS: 1405-10-3. Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amoxicillin sodium | 34642-77-8 | 98.0% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Thiamphenicol | 15318-45-3 | 99.6% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Geldanamycin 30562-34-6 10mM (in 1mL DMSO) Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-103364A 5mg Medchemexpress, C-021 (dihydrochloride) CAS:1784252-84-1 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More