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Filtered Search Results
Apexbio Technology LLC Streptozocin 18883-66-4 10mM (in 1mL DMSO)
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Streptozocin is an antibiotic derivative commonly utilized as an antitumor agent in biomedical research It exerts its biological function primarily through DNA alkylation resulting in targeted cellular toxicity Notably streptozocin selectively acts on pancreatic -cells by depleting intracellular nicotinamide adenine dinucleotide (NAD ) leading to dysregulated glucose metabolism and experimental induction of diabetes mellitus In addition streptozocin is frequently employed in vitro and in vivo to establish diabetic animal models for examination of diabetes-related complications and screening antidiabetic therapies Reported IC50 values vary depending on cell types and conditions with typical values ranging approximately from 11 to 25 M in pancreatic -cell lines
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Apexbio Technology LLC Amphotericin B 1397-89-3 10mM (in 1mL DMSO)
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Amphotericin B is a polyene antifungal antibiotic derived from Streptomyces nodosus It exerts its antifungal action primarily by binding sterols in fungal membranes forming pores that disrupt membrane integrity This binding induces altered ion permeability permitting movement of small ions including potassium and sodium across the membrane Additionally Amphotericin B stimulates inflammatory cytokine release in immune cells through interaction with Toll-like receptor 2 (TLR2) and CD14-dependent pathways Amphotericin B is used in biomedical research to investigate fungal infection mechanisms immune signaling events mediated by TLR pathways and prion-related disorders Its antifungal activity exhibits an IC50 range from 0 028 to 0 290 g/ml in vitro
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Medchemexpress LLC (S)-Leucic acid | 13748-90-8 | 99.2% | 132.16 | 500 MG
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(S)-Leucic acid is a metabolite of Leucine. It exhibits anabolic effects, specifically promoting muscle protein synthesis. Additionally, (S)-Leucic acid can be utilized in the diagnosis of pregnancy loss.
- Metabolite of Leucine
- Promotes muscle protein synthesis
- Can be used in the diagnosis of pregnancy loss
- Appears as a solid
- Color is white to off-white
- Shipped at room temperature in continental US
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
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Medchemexpress LLC Pretomanid-d4 | 1346617-34-2 | 99.8% | 363.28 | 10 MG
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Pretomanid-d4 is the deuterium labeled Pretomanid, an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. It exhibits a sub-micromolar MIC against M. tuberculosis (MTB), with MIC values against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates ranging from 0.015 to 0.25 μg/mL. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules as tracers for quantitation during drug development. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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eMolecules azido-tris(ethylenoxy)-L-alanine TFA Salt | 2054345-67-2 | | 1g
Broadpharm | azido-tris(ethylenoxy)-L-alanine TFA Salt | 1g | 340376876 | BP-23411 | 95.000 | 2054345-67-2 | | 262.266 | C9H18N4O5
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Ambeed S-3-1-9H-PURIN-6-YL AMINO
(S)-3-(1-((9H-Purin-6-yl)amino)ethyl)-
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Amsbio LLC Ampicillin, Sodium Salt
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Ampicillin Sodium Salt
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Medchemexpress LLC Thalidomide-PEG2-C2-NH2 (TFA) | 2097509-36-7 | 99.1% | 100 MG
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Thalidomide-PEG2-C2-NH2 (TFA) is a high-purity chemical compound, identified as an E3 ligase ligand-linker conjugate. It is designed for laboratory research purposes and exhibits chemical stability under recommended storage conditions.
- High purity of 99.1% (HPLC)
- Stable under recommended storage conditions
- E3 ligase ligand-linker conjugate
- Suitable for laboratory research
- Recommended storage at -20°C under nitrogen
- For solutions, store at -80°C for 6 months or -20°C for 1 month under nitrogen
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Medchemexpress LLC Streptozotocin | 18883-66-4 | 99.15% | 265.22 | 1 G
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Streptozotocin (STZ) is an antibiotic widely used in experimental animal models of induced diabetes. It enters B cells via the glucose transporter (GLUT2) and causes DNA alkylation, leading to the apoptosis of β cells.
- Used in experimental animal models of induced diabetes
- Suitable for constructing models of type 1 and type 2 diabetes
- Highly water-soluble
- Distributes widely throughout the body, including crossing the blood-brain barrier and placenta
- Induces cytotoxicity, oxidative stress, and mitochondrial dysfunction in HepG2 cells
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Research Products International Corp Actinomycin D [Actinomycin C1] [Dactinomycin], 10 Milligrams
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Actinomycin D, also known as Dactinomycin, is an antibiotic.
It works by binding to DNA, inhibiting both DNA and RNA synthesis. This interference with nucleic acid synthesis makes it effective against rapidly dividing cells, such as cancer cells.
Actinomycin D is used as a tool to study DNA and RNA synthesis, cell cycle progression, and cellular responses to DNA damage. Its ability to interfere with nucleic acid synthesis makes it valuable in understanding the molecular mechanisms of cell biology and cancer.
WARNING! This product can expose you to Actinomycin D, a chemical which is known to the State of California to cause cancer and developmental harm. For more information go to www.P65Warnings.ca.gov.
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Research Products International Corp Mitomycin C, 5 MG
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Mitomycin C is a potent antitumor antibiotic. It is derived from Streptomyces caespitosus and exhibits strong cytotoxic properties. It works by cross-linking DNA, inhibiting DNA synthesis, and inducing cell death. Mitomycin C finds applications in molecular biology and cell biology research. It is frequently employed as a DNA cross-linking agent in studies involving DNA damage and repair mechanisms.
Researchers use Mitomycin C to induce DNA adduct formation and study the cellular response to DNA damage. One notable feature of Mitomycin C is its ability to induce DNA cross-links in both dividing and non-dividing cells, making it useful for investigating cellular processes beyond actively dividing cells.
WARNING! This product can expose you to Mitomycin-C, a chemical which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.
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Medchemexpress LLC HY-A0096 100mg , Iloprost Ciloprost;ZK 36374 CAS:78919-13-8 Purity:98%
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Medchemexpress, HY-A0096 100mg Iloprost Ciloprost;ZK 36374 CAS:78919-13-8 Formula:C22H32O4 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Research Products International Corp Metronidazole, 100 Grams
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Metronidazole is a commonly used product in the life science marketplace with a broad range of applications.
It belongs to the class of drugs known as nitroimidazoles and exhibits potent antimicrobial activity against various anaerobic bacteria and parasites.
In the field of infectious diseases, metronidazole is primarily utilized to treat infections caused by anaerobic bacteria, such as Clostridium difficile, Bacteroides fragilis, and Helicobacter pylori.
WARNING! This product can expose you to Metronidazole, a chemical which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.
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Research Products International Corp OXYTETRACYCLINE HCL, 25GM
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Oxytetracycline Hydrochloride is a tetracycline antibiotic. Oxytetracycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing the attachment of aminoacyl-tRNA to the mRNA-ribosome complex. The interference disrupts the translation process and inhibits bacterial growth.
This antibiotic offers a broad spectrum of antibacterial activity against both Gram-positive and Gram-negative bacteria. Additionally, it can be used to study bacterial susceptibility patterns or as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic.
WARNING! This product can expose you to Ocytetracycline HCl, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
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eMolecules Tildipirosin | 328898-40-4 | | 50mg
Ambeed | Tildipirosin | 50mg | 598442216 | A262611 | | 328898-40-4 | | 734.032 | C41H71N3O8
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