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Filtered Search Results
Cayman Chemical ThIamphenIcol 50g
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An antibiotic derived from chloramphenicol that displays a similar spectrum of activity with enhanced potency
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Medchemexpress LLC [4-[[5-chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl- | 1700693-08-8 | MFCD29472241 | 98.0% | 416.86 g/mol | C19H21ClN6O3 | 10 MG
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JH-II-127 is an orally active, highly potent, selective, and brain-permeable inhibitor of leucine-rich repeat kinase 2 (LRRK2) used in preclinical research to probe LRRK2 signaling and Parkinson's disease models. It shows low-nanomolar activity against wild-type and mutant LRRK2 and has characterized solubility and storage profiles for in vitro and in vivo studies.
- Highly potent LRRK2 inhibition (low-nanomolar IC50 values).
- Selective activity against wild-type and mutant LRRK2 variants.
- Brain permeable, suitable for central nervous system studies.
- High purity solid with defined storage conditions for stability.
- Documented solubility protocols for in vitro and in vivo use.
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Biotang Inc IPTG 10 GM, P-806, CAS # 367-93-1. Purity > 99%, soluble in ethanol and water. Shipped at room temperature. Store at 2-8 degrees Celsius. Dioxane free. Mol. wt. 238.3.
IPTG 10 GM, P-806, CAS # 367-93-1. Purity > 99%, soluble in ethanol and water. Shipped at room temperature. Store at 2-8 degrees Celsius. Dioxane free. Mol. wt. 238.3.
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eMolecules 901751-47-1 | Medchem Express | iCRT3 | 5mg | 446258358 | HY-103705 | MFCD14766288 | 394.53 | C23H26N2O2S
Medchem Express | iCRT3 | 5mg | 446258358 | HY-103705 | 901751-47-1 | MFCD14766288 | 394.530 | C23H26N2O2S
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Medchemexpress LLC HY-10982 5mg Medchemexpress, Amonafide CAS:69408-81-7 Purity:>98%
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Medchemexpress, HY-10982 5mg Amonafide CAS:69408-81-7 Amonafide is a topoisomerase II inhibitor and DNA intercalator that induces apoptotic signaling by blocking the binding of Topo II to DNA. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Mitomycin C, 50-07-7, MFCD00078109, 10 mg
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MF: C15H18N4O5, MW: 334.33, Solubility: 16.7mg/mL in DMSO,insoluble in EtOH,insoluble in H2O, Synonyms: Ametycine. Mitomycin C, a kind of antibiotic isolated from Streptomyces caespitosus or Streptomyces lavendulae, inhibits DNA synthesis through covalent mitomycin C-DNA adduct with EC50 values of 0.14M in PC3 cells. Therefore, it was served as a chemotherapeutic agent that has demonstrated its antitumor activity and has been used widely in treatment of various cancers.
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Medchemexpress LLC Jak/hdac-in-1 | 2284621-75-4 | 98.6% | 450.32 g/mol | C19H21Cl2N7O2 | 100MG
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JAK/HDAC-IN-1 is a small-molecule dual inhibitor targeting JAK2 and histone deacetylase (HDAC) enzymes. It has reported low-nanomolar activity and shows antiproliferative and proapoptotic effects in hematological cell lines. The compound is supplied for research use only and is typically offered in small-mass quantities for in vitro studies.
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Apexbio Technology LLC Chloramphenicol(Synonyms: Chloromycetin, Levomycetin, Chlornitromycin, Fenicol, Amphicol, Kemicetine), 1g, CAS: 56-75-7.
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Chloramphenicol (CAS 56-75-7) is a small molecule antibiotic commonly utilized in molecular biology research It exerts anti-microbial activity by specifically binding to the bacterial 50S ribosomal subunit thereby inhibiting the peptidyl transferase reaction and subsequently blocking protein synthesis At elevated concentrations chloramphenicol may also impede DNA synthesis in eukaryotic cells In plasmid selection assays typical effective concentrations are approximately 25 g/ml for stringent plasmids and 170 g/ml for relaxed plasmids For laboratory storage chloramphenicol solutions are maintained at 4 C
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Medchemexpress LLC HY-13074 5mg Medchemexpress, VO-Ohpic (trihydrate) CAS:476310-60-8 Purity:>98%
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Medchemexpress, HY-13074 5mg VO-Ohpic (trihydrate) CAS:476310-60-8 VO-Ohpic trihydrate is a highly potent inhibitor of PTEN with an IC50 of 46±10 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-111444 5mg Medchemexpress, Auxinole CAS:86445-22-9 Purity:>98%
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Medchemexpress, HY-111444 5mg Auxinole CAS:86445-22-9 Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and so inhibits auxin-responsive gene expression. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Axitinib-d3 | 1126623-89-9 | 98.1% | 389.49 g/mol | C22H15D3N4OS | 5 MG
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Axitinib-d3 is a deuterium-labeled analog of axitinib supplied as an analytical standard for research and quantitative assays. It is intended as an internal standard or reference material for LC-MS and other analytical methods.
- Deuterium-labeled internal standard for quantitative assays.
- High chemical purity: 98.1%.
- Chemical formula C22H15D3N4OS; molecular weight 389.49 g/mol.
- CAS number 1126623-89-9 for unambiguous identification.
- Suitable for LC-MS, stability studies, and method development.
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Ubpbio Carbenicillin DisodiumSalt, 5G
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Carbenicillin is a semi-synthetic bactericidal antibiotic in the penicillin family. It primarily acts on Gram-negative bacteria. Carbenicillin is more stable than ampicillin and results in fewer satellite colonies on selection plates.
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Apexbio Technology LLC Valinomycin 2001-95-8 50mg
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Valinomycin (CAS 2001-95-8) is a small-molecule potassium ionophore targeting potassium ion transport It is designed to facilitate selective potassium ion translocation across lipid membranes thereby disrupting intracellular potassium homeostasis Valinomycin exerts its biological activity primarily through passive transport of potassium ions leading to mitochondrial membrane depolarization and induction of apoptotic pathways In in vitro studies using Chinese hamster ovary (CHO) cells valinomycin induces apoptosis within 12 hours of exposure with an IC50 value around or below 1 M in cell-based assays Based on these pharmacological properties valinomycin holds research potential in studies of mitochondrial-mediated apoptosis and ion homeostasis
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eMolecules 1370554-01-0 | Medchem Express | Ciliobrevin D | 5mg | 518571036 | HY-122632 | 392.62 | C17H8Cl3N3O2
Ambeed | 4-Bromobenzene-12-diol | 1g | 490495716 | A114079 | 17345-77-6 | MFCD00869769 | 189.008 | C6H5BrO2
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Medchemexpress LLC HY-10181 200mg Medchemexpress, Dasatinib CAS:302962-49-8 Purity:>98%
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Medchemexpress, HY-10181 200mg Dasatinib CAS:302962-49-8 Dasatinib (BMS-354825) is a potent and orally active dual Bcr-Abl and Src family tyrosine kinase inhibitor with IC50s of 0.6 nM, 0.8 nM, respectively. Dasatinib also inhibits Abl, Src, Fyn, c-Kit and c-KitD816V with IC50s of 2.8 nM, 79 nM and 37 nM, respectively. Dasatinib also induces apoptosis and autophagy. Dasatinib shows potently antitumor activity and has the potential for chronic myelogenous leukemia (CML) treatment[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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