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Filtered Search Results
Medchemexpress LLC HY-100735 5mg Medchemexpress, C 87 CAS:332420-90-3 Purity:>98%
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Medchemexpress, HY-100735 5mg C 87 CAS:332420-90-3 C87 is a novel small-molecule TNFα inhibitor; potently inhibits TNFα-induced cytotoxicity with an IC 50 of 8.73 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sciencell Research Laboratories P/S(PEN/STREPTOMYCIN SOLN) 5ML
Penicillin/Streptomycin Solution 5 ml
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Medchemexpress LLC HY-114415 5mg Medchemexpress, AWZ1066S CAS:2239272-16-1 Purity:>98%
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Medchemexpress, HY-114415 5mg AWZ1066S CAS:2239272-16-1 AWZ1066S is a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis, with an EC 50 of 2.5 nM in cell assay [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Temsirolimus >=98% (HPLC) | 162635-04-3 | MFCD00934421 | 25MG
Temsirolimus >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 1030.29 | 162635-04-3 | MFCD00934421 | 25MG
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Medchemexpress LLC HY-14644 10mg Medchemexpress, Apilimod CAS:541550-19-0 Purity:>98%
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Medchemexpress, HY-14644 10mg Apilimod CAS:541550-19-0 Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively. Apilimod is a potent and highly selective PIKfyve inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Calhex 231 hydrochloride | 2387505-78-2 | MFCD22580412 | 99.8% | 443.41 g/mol | C25H28Cl2N2O | 25 MG
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Calhex 231 hydrochloride is a selective negative allosteric modulator of the calcium-sensing receptor (CaSR) used as a research reagent to investigate CaSR-mediated signaling and related pathologies. It blocks Ca2+-induced inositol phosphate accumulation and has been applied in cellular and in vivo studies of traumatic hemorrhagic shock and diabetic cardiomyopathy.
- Selective negative allosteric modulation of CaSR.
- Reported IC50 ≈ 0.39 μM for human CaSR activity.
- High chemical purity (~99.8%) suitable for research use.
- Solid form, soluble in DMSO for biological assays.
- Storage stability in solvent: -80°C up to 6 months, -20°C up to 1 month.
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![Medchemexpress LLC 1-methyl-5-(2'-methyl-[1,1'-biphenyl]-4-yl)-1H-benzo[d]triazole-7-carboxylic acid | 1623416-31-8 | MFCD33023454 | 98.3% | C21H17N3O2 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000258405.png-250.jpg)
Medchemexpress LLC 1-methyl-5-(2'-methyl-[1,1'-biphenyl]-4-yl)-1H-benzo[d]triazole-7-carboxylic acid | 1623416-31-8 | MFCD33023454 | 98.3% | C21H17N3O2 | 10MG
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AG-636 is a potent, reversible, selective, and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 17 nM. It is supplied as a high-purity research reagent for biochemical and cellular studies investigating pyrimidine biosynthesis and anticancer pathways.
- Potent DHODH inhibition (IC50 17 nM).
- Reversible and orally active mechanism of action.
- High purity for research applications.
- Molecular formula C21H17N3O2.
- Available as a small research pack for laboratory use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide | 579-38-4 | 99.7% | 50MG
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2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide | 579-38-4 | 99.7% | 50MG
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Chem-Impex International, Inc. Ampicillin sodium salt | 69-52-3 | MFCD00064313 | 25G
Ampicillin sodium salt, 69-52-3, MFCD00064313, 25G
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Medchemexpress LLC Tylosin | 1401-69-0 | 98.0% | 50 MG
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Tylosin is a macrolide antibiotic naturally produced by Streptomyces fradiae. It exhibits potent antimicrobial activity against Gram-positive bacteria and functions by binding to the 23S rRNA of the bacterial ribosomal 50S subunit, preventing protein synthesis.
- Effectively combats Gram-positive bacteria
- Used as a feed additive to promote animal growth
- Applied in veterinary medicine to treat bacterial dysentery and respiratory diseases in poultry, pigs, and cattle
- Inhibits protein synthesis by binding to bacterial ribosomal 50S subunit
- Reduces elevated TNF-α and IL-1β levels and increases IL-10 levels in LPS-treated mice
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Medchemexpress LLC HY-111138 10mg Medchemexpress, CZC-8004 CAS:916603-07-1 Purity:>98%
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Medchemexpress, HY-111138 10mg CZC-8004 CAS:916603-07-1 CZC-8004 is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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STEMCELL Technologies Puromycin (Dihydrochloride), Size: 50 mg
Puromycin is an aminonucleoside antibiotic, derived from Streptomyces alboniger, which acts as a protein synthesis inhibitor. It binds to the target ribosome site A, where it is transferred to the growing polypeptide chain causing premature chain termination (Lührmann et al.; Rodriguez-Fonseca et al.; Azzam & Algranati). A biologically inactive form is generated when puromycin is N-acetylated by puromycin-N-acetyltransferase, allowing this gene to be used as a selective resistance marker (Vara et al. 1985).CELL LINE DEVELOPMENT· Selects for cells expressing puromycin-N-acetyltransferase resistance gene as a research tool (de la Luna & Ortín; Iwaki et al.).· Useful in CRISPR/Cas9 mammalian gene editing by selecting for successful Cas9-induced knock-in with puromycin resistance gene (Park et al.). CANCER RESEARCH· Possesses anti-tumor activity when tested against numerous cell lines (Foley & Eagle).
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Selleck Chemical LLC Lirametostat CPI-1205-2mg
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Lirametostat (CPI-1205) is an orally available selective inhibitor of the histone lysine methyltransferase EZH2 with IC50 values of 2 nM and 52 nM for EZH2 and EZH1 respectively. It has potential antineoplastic activity.
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Medchemexpress LLC HY-17465 10mg Medchemexpress, Glycopyrrolate CAS:596-51-0 Purity:>98%
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Medchemexpress, HY-17465 10mg Glycopyrrolate CAS:596-51-0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Geldanamycin | 30562-34-6 | C29H40N2O9 | 50 MG
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Geldanamycin is a potent Hsp90 inhibitor derived from *Streptomyces hygroscopicus*, exhibiting significant antimicrobial activity against various bacteria and anti-influenza virus H5N1 properties. It acts by binding to the N-terminal ATPase domain of Hsp90, thereby inhibiting its chaperone function and inducing apoptotic tumor cell death.
- Hsp90 inhibitor
- Antimicrobial activity
- Anti-influenza virus H5N1 activities
- Induces tumor cell death
- Light yellow to orange solid appearance
- High purity (99.43%)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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