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Filtered Search Results
Apexbio Technology LLC Atglistatin,10mg CAS# 1469924-27-3
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Atglistatin is a potent and selective inhibitor of ATGL with IC50 value of 0.7 μM [1]. Adipose triglyceride lipase (ATGL) is a rate-limiting enzyme in the mobilization of fatty acids from cellular triglyceride stores. Deregulated fatty acid metabolism may lead to metabolic disorders and dyslipidemic [1]. Atglistatin is a potent and selective ATGL inhibitor. In lysates from E. coli overexpressing ATGL, atglistatin inhibited ATGL activity with IC50 value of 0.7 μM. Atglistatin at concentrations up to 50 μM had no cytotoxicity. Also, atglistatin inhibited ATGL with Ki value of 355 nM in a competitive way. In white adipose tissue (WAT) lysates of wild-type mice, atglistatin inhibited triacylglycerol (TG) hydrolase activity by 78%. The combination of Atglistatin and the HSL inhibitor Hi 76-007917 inhibited TG hydrolase activity by 95%. Other sizes are also available. Please inqury us for quote.
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Medchemexpress LLC NITD-2 | 1197896-79-9 | MFCD34471209 | 99.4% | C23H19N3O4S | 10MG
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NITD-2 is a small-molecule research inhibitor of dengue virus RNA-dependent RNA polymerase (RdRp). It inhibits RdRp-mediated RNA elongation and is primarily used in biochemical antiviral studies; the compound exhibits limited cellular permeability and is typically prepared in DMSO for assays.
- Inhibits dengue virus RNA-dependent RNA polymerase (RdRp)-mediated RNA elongation.
- Limited cell membrane permeability; suitable for in vitro assays and formulated in vivo dosing.
- High purity appropriate for biochemical and antiviral assays.
- Soluble in DMSO at high concentrations; ultrasonic agitation may improve solubility.
- Stable as a powder when stored under recommended cold conditions.
- Available in small milligram pack sizes for research use.
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Medchemexpress LLC HY-101451 10mg Medchemexpress, PBIT CAS:2514-30-9 Purity:>98%
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Medchemexpress, HY-101451 10mg PBIT CAS:2514-30-9 PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 ( JARID1 ) enzymes. PBIT inhibits JARID1B ( KDM5B or PLU1 ) histone demethylase with an IC 50 of about 3 μM . PBIT also inhibits JARID1A and JARID1C with IC 50 s of 6 and 4.9 μM, respectively [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100229 10mg Medchemexpress, Aloxistatin CAS:88321-09-9 Purity:>98%
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Medchemexpress, HY-100229 10mg Aloxistatin CAS:88321-09-9 Aloxistatin (E64d) is a cell-permeable and irreversible broad-spectrum cysteine protease inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100033 10mg Medchemexpress, NSC5844 CAS:140926-75-6 Purity:>98%
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Medchemexpress, HY-100033 10mg NSC5844 CAS:140926-75-6 NSC5844 is a 4-aminoquinoline derivative, with antitumor and antimalarial activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100619A 10mg Medchemexpress, BMS-986020 (sodium) CAS:1380650-53-2 Purity:>98%
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Medchemexpress, HY-100619A 10mg BMS-986020 (sodium) CAS:1380650-53-2 BMS-986020 sodium is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist. BMS-986020 sodium inhibits bile acid and phospholipid transporters with IC50s of 4.8 µM, 6.2 µM, and 7.5 µM for BSEP, MRP4, and MDR3, respectively. BMS-986020 sodium has the potential for the treatment of idiopathic pulmonary fibrosis (IPF)[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-A0082 100mg Medchemexpress, Diphenidol (hydrochloride) Difenidol hydrochloride CAS:3254-89-5 Purity:98%
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Medchemexpress,HY-A0082 100mg Diphenidol (hydrochloride) Difenidol hydrochloride CAS:3254-89-5 Formula:C21H28ClNO Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-103036 10mg Medchemexpress, BET bromodomain inhibitor CAS:1505453-59-7 Purity:>98%
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Medchemexpress, HY-103036 10mg BET bromodomain inhibitor CAS:1505453-59-7 BET bromodomain inhibitor is a potent BET inhibitor extracted from patent WO/2015/153871A2, compound example 11. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 438542-15-5 | Medchem Express | GW274150 (phosphate) | 5mg | 518571022 | HY-12119A | 317.3 | C8H20N3O6PS
ChemScene | 7-Amino-5-fluoroindolin-2-one | 250mg | 632283083 | CS-0150077 | 945381-62-4 | MFCD13193359 | 166.155 | C8H7FN2O
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eMolecules 103408-45-3 | Pyrimido[1,2-a]purin-10(1H)-one | MFCD03413766 | 250mg
ChemScene | 5-Bromo-4-chloropicolinic acid | 100mg | 569148190 | CS-W018684 | 1060802-25-6 | MFCD13189053 | 236.450 | C6H3BrClNO2
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Medchemexpress LLC HY-15581 5mg Medchemexpress, MMAD CAS:203849-91-6 Purity:>98%
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Medchemexpress, HY-15581 5mg MMAD CAS:203849-91-6 MMAD is a potent tubulin inhibitor, is a toxin payload in antibody drug conjugates (ADCs). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-13410 5mg Medchemexpress, Xanomeline (oxalate) CAS:141064-23-5 Purity:>98%
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Medchemexpress, HY-13410 5mg Xanomeline (oxalate) CAS:141064-23-5 Xanomeline oxalate (LY246708 oxalate) is a potent and selective muscarinic receptor agonist (SMRA) and stimulates phosphoinositide hydrolysis in vivo. Xanomeline oxalate can be used for the research of Alzheimer’s disease. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 18550-98-6 | Medchem Express | 3PO | 5mg | 446270433 | HY-19824 | MFCD00224002 | 210.236 | C13H10N2O
Ambeed | (S)-2-Amino-3-(1H-indol-3-yl)propan-1-ol | 1g | 586450763 | A109445 | 2899-29-8 | MFCD00037970 | 190.246 | C11H14N2O
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eMolecules 36457-20-2 | Butylparaben sodium salt | Combi-Blocks | MFCD01661516 | 216.212 | C11H13NaO3 | 98.000 | [Na+].CCCCOC(=O)c1ccc([O-])cc1 | 5g | 205386319
Butylparaben sodium salt | Combi-Blocks | 36457-20-2 | MFCD01661516 | 216.212 | C11H13NaO3 | 98.000 | [Na+].CCCCOC(=O)c1ccc([O-])cc1 | 5g | 205386319
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Apexbio Technology LLC Tobramycin 32986-56-4 50mg
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Tobramycin (CAS 32986-56-4) is a small-molecule inhibitor targeting the bacterial ribosomal 30S subunit It is designed to interfere with protein synthesis thereby inhibiting bacterial growth Tobramycin exerts its biological activity primarily through specific binding to the 30S subunit preventing translation and subsequent bacterial proliferation In in vitro and in vivo studies Tobramycin demonstrates inhibitory activity with reported IC50 values ranging from 0 2 g/mL to 4 g/mL depending on the bacterial strain and experimental conditions Based on these pharmacological properties Tobramycin holds research potential in the investigation of bacterial infection mechanisms including studies of Pseudomonas aeruginosa and models of bacterial pneumonia as well as in the exploration of bacterial resistance mechanisms
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