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Filtered Search Results
Medchemexpress LLC Lyn-1604 dihydrochloride | 2310109-38-5 | 99.6% | 657.54 g·mol-1 | C33H45Cl4N3O2 | 10 MG
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LYN-1604 dihydrochloride is a small-molecule activator of UNC-51-like kinase 1 (ULK1) used to study autophagy and triple-negative breast cancer. Supplied as the dihydrochloride salt, it is provided at high purity for in vitro biochemical and cellular assays.
- Activates ULK1 with nanomolar EC50 (18.94 nM).
- High purity solid suitable for biochemical and cellular research.
- Available as small-mass solids and pre-made DMSO solution for convenience.
- Stable when stored sealed at 4°C; in solvent store at -80°C for long term.
- Dihydrochloride salt form improves solubility for assay preparation.
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Medchemexpress LLC Alpha-methyl-4-propylphenylacetic acid | 3585-47-5 | 98.0% | 192.25 g/mol | C12H16O2 | 5 MG
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Ibuprofen impurity 1 (alpha-methyl-4-propylphenylacetic acid) is a characterized impurity of ibuprofen provided for research and analytical use. It is a solid organic acid with formula C12H16O2 and molecular weight 192.25 g/mol, supplied at high reported purity for impurity profiling, method development, and assay control in medicinal chemistry and COX inhibition studies.
- High reported purity suitable for analytical applications.
- Solid form for straightforward handling and storage.
- Appropriate for impurity profiling and analytical method development.
- Molecular formula C12H16O2 and molar mass 192.25 g/mol.
- Available in small research pack sizes for laboratory use.
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Medchemexpress LLC Butanedioic acid, compd. with cabamiquine (6-fluoro quinoline carboxamide) | 2444781-71-7 | 99.8% | 580.65 | C31H37FN4O6 | 10 MG
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Cabamiquine succinate is the succinate salt of cabamiquine (DDD107498), a potent orally active antimalarial research compound that inhibits Plasmodium protein synthesis via eEF2/CaMKIII. It is supplied as a white to off-white solid with high analytical purity and intended for laboratory research.
- High purity: 99.8% (LCMS).
- Suitable for in vitro and preclinical assays targeting Plasmodium species.
- Soluble in DMSO (≈135 mg/mL); ultrasonic agitation may be required.
- Storage: sealed, away from moisture and light; in solvent store -80°C (6 months) or -20°C (1 month).
- Available in small mg-scale packages for research applications.
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Medchemexpress LLC ICA-105665 (PF-04895162) | 2694728-63-5 | 99.9% | 355.34 | C19H15F2N3O2 | 25MG
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ICA-105665 is an orally active small-molecule opener of neuronal Kv7 potassium channels (Kv7.2/7.3 and Kv7.3/7.5) used in research. It penetrates the blood-brain barrier, exhibits antiseizure activity, and has reported effects on liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 311 μM). The compound is supplied as a high-purity white to off-white powder suitable for in vitro and in vivo studies.
- Cas registry number: 2694728-63-5.
- Mechanism of action: opens Kv7.2/7.3 and Kv7.3/7.5 potassium channels.
- Chemical formula: C19H15F2N3O2.
- Molecular weight: 355.34 g/mol.
- Purity: 99.9% (rounded).
- Appearance and form: white to off-white powder.
- Solubility: soluble in DMSO at 250 mg/mL; ultrasonic assistance recommended.
- Storage: store powder at -20°C for long-term stability; store solutions at -80°C for short-term use.
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Medchemexpress LLC Lumefantrine-d9 | 2477594-24-2 | 97.0% | 1 MG
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Lumefantrine-d9 is the deuterium-labeled version of Lumefantrine, an antimalarial drug. Lumefantrine is used in combination with Artemether, forming artemether-lumefantrine (AL), which serves as a first- and second-line antimalarial drug. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules as tracers for quantitation during drug development.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Apexbio Technology LLC Anidulafungin(Synonyms: Eraxis, Ecalta, LY303366, VER-002, Anidulafungin acetate, V-echinocandin, Vicuron echinocandin), 100mg, CAS: 166663-25-8.
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Anidulafungin (CAS 166663-25-8) also known as LY-303366 is a semisynthetic derivative of echinocandin B exhibiting antifungal activity It acts by inhibiting fungal cell wall synthesis through interference with the enzyme -(1 3)-D-glucan synthase In vitro analyses demonstrate that Anidulafungin inhibits various Candida species including C albicans C glabrata C tropicalis and C parapsilosis (MIC90 0 08 0 32 0 32 5 12 g/ml respectively) as well as Aspergillus species (MIC90 0 02 g/ml) Lack of significant efficacy was shown against Cryptococcus neoformans and Blastomyces dermatitidis This compound is useful for research exploring antifungal resistance mechanisms and therapeutics
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Bio IVT Torpedo Rodent Antibiotic Mix, 5.5 mL
Torpedo Rodent Antibiotic Mix, 5.5 mL.
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STEMCELL Technologies Rapamycin, Size: 10 mg
Inhibit mammalian target of rapamycin (mTOR) signaling with Rapamycin. This FKBP-12-inhibiting antibiotic shows antifungal activity against Candida albicans and other fungi (Vézina et al. J Antibiot (Tokyo), 1975); inhibits growth of MDA-MB-468 human breast cancer cells in vitro (Akcakanat et al. Mol Cancer, 2009; and inhibits tumor growth in a mouse xenograft model in vivo (Akcakanat et al. Mol Cancer, 2009). Its immunosuppressive effects are mediated through inhibition of IL-2 signaling that is critical for T-cell proliferation and activation (Gibbons et al. Semin Oncol, 2009; Kay et al. Immunology, 1991). Rapamycin is supplied as a crystalline solid with ≥ 95% purity; Molecular weight 914.2 g/mol; CAS number 53123-88-9. Visit STEMCELL.com for more information and related products.
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STEMCELL Technologies Mitomycin C, Size: 10 mg
Inhibit DNA synthesis and mutagenesis, stimulate genetic recombination, and induce DNA repair (Tomasz. Chem Biol, 1995) with Mitomycin C. This antibiotic, which acts as a double-stranded DNA alkylating agent, covalently cross links DNA, inhibiting DNA synthesis and cell proliferation. It acts by way of reductive activation either through low pH or NAD(P)H:quinone oxidoreductase (DT-diaphorase) or NADH cytochrome c reductase (Mao et al. Chem Biol, 1999; Cummings et al. Biochem Pharmacol, 1998). Mitomycin C can mitotically inactivate mouse embryonic fibroblasts (MEFs) for use as feeder cell layers in embryonic stem cell co-culture systems (Bryja et al. Nat Protoc, 2006). Mitomycin C is supplied as a crystalline solid with ≥ 98% purity; Molecular weight 334.3 g/mol; CAS number 50-07-7. Visit STEMCELL.com for more information and related products.
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eMolecules 1430208-73-3 | Medchem Express | 1A-116 | 5mg | 446258536 | HY-104064 | 307.32 | C16H16F3N3
Medchem Express | GNE-371 | 5mg | 559839461 | HY-112803 | 1926986-36-8 | 431.496 | C24H25N5O3
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
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Medchemexpress LLC HY-100775 5mg Medchemexpress, PBI-4050 (sodium salt) CAS:1254472-97-3 Purity:>98%
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Medchemexpress, HY-100775 5mg PBI-4050 (sodium salt) CAS:1254472-97-3 PBI-4050 sodium salt acts as an agonist for GPR40 and as an antagonist or inverse agonist for GPR84 . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Rifaximin (Xifaxan), 500mg. Cas: 80621-81-4 MFCD: MFCD00864973. RNA synthesis inhibitor, PXR activator
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Rifaximin, a rifamycin derivative, is a nonabsorbable antibiotic. Rifaximin inhibits RNA synthesis by binding the subunit of the bacterial DNA-dependent RNA polymerase. Other sizes are available. Please inqury us for quote.
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AdipoGen Violacein,Chemical. CAS: 548-54-9
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Violacein, AdipoGen Life Sciences. Chemical. CAS: 548-54-9. Formula: C20H13N3O3. MW: 343.3. Isolated from Chromobacterium violaceum. Antibacterial, antifungal and antiprotozoal agent. Quorum sensing metabolite. Antitumor compound. Protective against UV-C irradiation. Possesses immunomodulatory, analgesic and antipyretic activity. Indole-derived purple-colored pigment (free of deoxyviolacein). 548-54-9
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Medchemexpress LLC L-homocysteine, S-[2-[(1-iminoethyl)amino]ethyl]-, phosphate (1:1) | 438542-15-5 | 98.0% | 100 MG
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GW274150 phosphate is a potent, selective, orally active NADPH-dependent inhibitor of inducible nitric oxide synthase (iNOS) used in research to probe iNOS-mediated signaling and inflammatory responses (human IC50 = 2.19 μM; Kd = 40 nM).
- Potent iNOS inhibitor with reported human IC50 2.19 μM and Kd 40 nM.
- High reported purity: 98.0% (LCMS).
- Molecular weight 317.30; formula C8H20N3O6PS.
- White to off-white solid; soluble in water and PBS with ultrasonic or heating assistance.
- Storage recommendations: keep dry at 4°C; in solution store -80°C (6 months) or -20°C (1 month).
- For research use only; not for human or clinical use.
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Medchemexpress LLC Cdk5 inhibitor 20-223 | 865317-30-2 | MFCD32857141 | 99.6% | 305.37 | C19H19N3O | 25MG
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CDK5 inhibitor 20-223 is a small-molecule kinase inhibitor active against CDK2 and CDK5, with low-nanomolar enzymatic potency and demonstrated cellular activity in colorectal cancer models. It is supplied as a light yellow to yellow solid for laboratory research, provided with high purity and recommended cold storage for long-term stability.
- Potent CDK2 and CDK5 inhibition with IC50s of ~6.0 nM and ~8.8 nM.
- Demonstrated cellular activity in colorectal cancer cell lines.
- High purity suitable for research applications.
- Light yellow to yellow solid for ease of handling.
- Molecular formula C19H19N3O and molecular weight 305.37.
- Recommended cold storage for long-term stability.
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