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Filtered Search Results
Medchemexpress LLC N-(4-mesitylthiazol-2-yl)benzamide | 1001753-24-7 | 99.5% | 322.42 | C19H18N2OS | 25 MG
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INH6 is a small-molecule Nek2/Hec1 inhibitor that inactivates Hec1/Nek2 function via protein degradation, leading to chromosome missegregation and cell death. It inhibits HeLa cell growth with an IC50 of 2.4 μM and produces mitotic defects and apoptosis in treated cells.
- Potent Nek2/Hec1 inhibition (IC50 2.4 μM).
- Inactivates Hec1/Nek2 through protein degradation, causing chromosome missegregation.
- Induces mitotic defects and apoptosis in cultured cells (~20% apoptotic cells at 72 h).
- Solid, white to off-white powder; soluble in DMSO (50 mg/mL) and in 10% DMSO/90% corn oil for animal dosing.
- Stable as powder at -20°C (3 years) and 4°C (2 years); in solvent stability varies by temperature.
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Medchemexpress LLC 5-(3,3-difluorocyclobutyl)-3-[4-[4-methyl-5-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-3-yl] | 935273-79-3 | MFCD30343842 | 99.2% | 493.47 g/mol | C24H24F5N5O | 25 MG
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MK-4101 is a small-molecule Smoothened (SMO) antagonist that inhibits the hedgehog signaling pathway and demonstrates antiproliferative and pro-apoptotic activity in tumor cell models. It is supplied for research use and is characterized by defined molecular properties and high analytical purity.
- Demonstrated antiproliferative and pro-apoptotic activity in cancer cell models.
- High purity (≈99.2%).
- Molecular weight 493.47 g/mol and formula C24H24F5N5O.
- Soluble in DMSO (≥50 mg/mL) for preparation of stock solutions.
- Recommended storage conditions for stability in powder and solution forms.
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Sigma Aldrich Fine Chemicals Biosciences S(+)-gamma-Vigabatrin solid | 74046-07-4 | MFCD00274076 | 5MG
S(+)-gamma-Vigabatrin solid | Mol Wt: 129.16 | 74046-07-4 | MFCD00274076 | 5MG
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eMolecules Medchem Express / Artefenomel / 5mg / 482204426 / HY-16762 / / 1029939-86-3 / [null] / 469.622 / C28H39NO5
Medchem Express / Artefenomel / 5mg / 482204426 / HY-16762 / / 1029939-86-3 / [null] / 469.622 / C28H39NO5
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Medchemexpress LLC HY-19657 50mg Medchemexpress, Oxypurinol CAS:2465-59-0 Purity:>98%
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Medchemexpress, HY-19657 50mg Oxypurinol CAS:2465-59-0 Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Pretomanid-d4 | 1346617-34-2 | 99.8% | 363.28 | 10 MG
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Pretomanid-d4 is the deuterium labeled Pretomanid, an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. It exhibits a sub-micromolar MIC against M. tuberculosis (MTB), with MIC values against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates ranging from 0.015 to 0.25 μg/mL. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules as tracers for quantitation during drug development. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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CPC Scientific H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2 (trifluoroacetate salt) 1MG
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ONE-LETTER SEQUENCE: AVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTA-NH2MOLECULAR FORMULA: C180H288N58O47MOLECULAR WEIGHT:4016.6STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [112955-31-4], RESEARCH AREA: OsteoporosisREFERENCES: N. Horvichi et al., Science, 238, 1566 (1987); B.E. Kemp et al., Science, 238, 1568 (1987)
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Apexbio Technology LLC Tolvaptan 150683-30-0 5mg
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Tolvaptan (CAS 150683-30-0) is a selective orally active antagonist of the arginine vasopressin (AVP) V2 receptor In binding assays using HeLa cells expressing human AVP receptor subtypes tolvaptan exhibits high affinity for the V2 receptor (Ki 0 43 nM) and substantially lower affinity for the V1a receptor (Ki 12 3 nM) with minimal activity at V1B and other off-target receptors or ion channels Tolvaptan inhibits AVP-induced cAMP accumulation with an IC50 of 8 nM In animal models administration of tolvaptan increases urine output and serum sodium and elevates plasma sodium while reducing mortality in hyponatremic rats This compound is widely utilized in research exploring water balance AVP signaling and hyponatremia mechanisms
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Apexbio Technology LLC Amoxicillin trihydrate 61336-70-7 1g
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Amoxicillin trihydrate (CAS 61336-70-7) is a small-molecule inhibitor targeting bacterial cell wall synthesis It is designed to inhibit peptidoglycan cross-linking thereby disrupting bacterial cell wall biosynthesis and resulting in cell lysis Amoxicillin trihydrate exerts its biological activity primarily through inhibition of bacterial transpeptidase enzymes involved in cell wall synthesis In in vitro studies Amoxicillin trihydrate demonstrates bactericidal activity with reported minimum inhibitory concentration (MIC) values of approximately 0 01 g/ml for Streptococcus viridans 0 25 g/ml for Bacillus anthracis and 50 g/ml for Retterella indica Based on these pharmacological properties Amoxicillin trihydrate holds research potential in antibacterial susceptibility testing microbial growth inhibition studies and in vitro pharmacological investigations
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eMolecules Retapamulin | 224452-66-8 | MFCD11045316 | 5g
Combi-Blocks | Retapamulin | 5g | 249358665 | QB-7392 | 98.000 | 224452-66-8 | MFCD11045316 | 517.770 | C30H47NO4S
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Medchemexpress LLC HY-106024B 200mg Medchemexpress, Alagebrium chloride ALT711 CAS:341028-37-3 Purity:98%
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Medchemexpress,HY-106024B 200mg Alagebrium chloride ALT711 CAS:341028-37-3 Formula:C13H14ClNOS Alagebrium chloride is an advanced glycation end product (AGE) inhibitor. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules Medchem Express / SC66 / 5mg / 446270447 / HY-19832 / / 871361-88-5 / MFCD05025493 / 276.339 / C18H16N2O
Medchem Express / SC66 / 5mg / 446270447 / HY-19832 / / 871361-88-5 / MFCD05025493 / 276.339 / C18H16N2O
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Medchemexpress LLC HY-B0246 500mg , Carbamazepine CBZ;NSC 169864 CAS:298-46-4 Purity:98%
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Medchemexpress, HY-B0246 500mg Carbamazepine CBZ;NSC 169864 CAS:298-46-4 Formula:C15H12N2O Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-121832 5mg Medchemexpress, DDX3-IN-1 CAS:1919828-83-3 Purity:>98%
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Medchemexpress, HY-121832 5mg DDX3-IN-1 CAS:1919828-83-3 DDX3-IN-1 (Compound 16f) is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC 50 s of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Cefuroxime Axetil United States Pharmacopeia (USP) Reference Standard | 64544-07-6 | MFCD00864991 | 350MG
Cefuroxime Axetil United States Pharmacopeia (USP) Reference Standard | Mol Wt: 510.47 | 64544-07-6 | MFCD00864991 | 350MG
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