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Heat Stable FGF-basic Human is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family Like other FGF family members FGF-basic has the trefoil structure In vivo FGF-basic is produced by a variety of cells including cardiomyocytes fibroblasts and vascular cells FGF-basic regulates a variety of processes including cell proliferation differentiation survival adhesion motility apoptosis limb formation and wound healing FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling The angiogenic effects of FGF-basic can produce beneficial cardioprotection during acute heart injury
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