Cell Culture Growth Factors and Hormones
STEMCELL Technologies Human Recombinant PDGF-AA, Size: 10 µg
Use platelet-derived growth factor (PDGF) AA to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into oligodendrocyte precursor cells (Piao et al. Cell Stem Cell, 2015). PDGF is a dimeric glycoprotein that signals through the receptor tyrosine kinases PDGFRα and PDGFRβ. It is a potent mitogen for cells of mesenchymal origin and induces migration through signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim et al. Growth Factors, 2007). PDGF-AA mediates proliferation of oligodendrocyte progenitor cells and oligodendrocyte lineage differentiation through the activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2) (Hu et al. Neuroscience, 2008). Human recombinant PDGF-AA from STEMCELL comes lyophilized with ≥ 95% purity; EC50 ≤ 50 ng/mL; endotoxin levels verified ≤ 1 EU/μg protein. Alternative names: GDGF, Glioma-derived growth factor, ODGF, Osteosarcoma-derived growth factor, Platelet-derived growth factor-AA.
Medchemexpress LLC IGF-I R Human HEK2 10ug
IGF-I receptor (IGF1R) mediates insulin-like growth factor effects binding strongly to IGF1 Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways influencing cell survival protein synthesis and proliferation IGF1R also signals through JAK/STAT inhibiting JNK activation Hybrid receptors show variable binding to IGF1 and insulin IGF-I R Protein Human (HEK293 His) is the recombinant human-derived IGF-I R protein expressed by HEK293 with C-6 His labeled tag
Medchemexpress LLC GDNF Human HEK293 10ug
Glial-cell-line-derived neurotrophic factor (GDNF) a neurotrophic factor belongs to the GDNF family ligands (GFLs) promotes survival of dopamine neurons GDNF demonstrates a variety of neuroprotective roles for mammalian neurons[1] GDNF Protein Human (HEK293) is produced in HEK293 cells and consists of 103 amino acids (R83-I185)
Biolegend PE/Cyanine7 anti-human LAP TGF
PE/Cyanine7 anti-human LAP (TGF-β1) [S20006A]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests
Sema-3E and Plexin D1 Receptor Antibody Sampler Kit, ECM Biosciences
The Sema-3E and Plexin D1 Receptor kit can be used to monitor the expression of Sema-3E and its receptor Plexin D1. The kit has an N-terminal region Sema-3E antibody, and Plexin D1 antibodies for detecting two regions in the cytoplasmic domain and a region in the extracellular Sema domain. The kit also includes secondary reagent for rabbit polyclonal antibody detection. Applications: WB, E; Species Reactivity: Hu, Rt, Ms
Medchemexpress LLC HY-P7198 10ug Medchemexpress, I-309/CCL1 (CHO-expressed), Human CAS: Purity:>98%
Medchemexpress, HY-116282B 100mg Dextran sulfate sodium salt (MW 16000-24000) CAS:9011-18-1 Dextran sulfate sodium salt (MW 16000-24000) is a is a polymer of anhydroglucose with the molecular weight range of 16000-24000. Dextran sulfate sodium salt inhibits the replication of the human immunodeficiency virus by preventing the adsorption of the virus into host cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-P7271 10ug Medchemexpress, NGFR (HEK293-expressed), Human CAS: Purity:>98%
Medchemexpress, HY-116330A 500ug Hyperforin (dicyclohexylammonium salt) CAS:238074-03-8 Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin dicyclohexylammonium salt modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt shows antidepressant effect. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-P7223 10ug Medchemexpress, IL-6R (CHO-expressed), Human CAS: Purity:>98%
Medchemexpress, HY-116282D 100mg Dextran sulfate sodium salt (MW 450000-550000) CAS:9011-18-1 Dextran sulfate sodium salt (MW 450000-550000) is a is a polymer of anhydroglucose with the molecular weight range of 450000-550000. Dextran sulfate sodium salt inhibits the replication of the human immunodeficiency virus by preventing the adsorption of the virus into host cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC IL-23 Rat HEK293 10ug
IL-23 alpha protein has cytokine activity and binds to the interleukin 23 receptor It regulates cytokine production lymphocyte activation and peptidyl tyrosine phosphorylation IL-23 Protein Rat (HEK293 His) is a recombinant protein dimer complex containing rat-derived IL-23 alpha IL-12 beta Heterodimer protein expressed by HEK293 with C-10 His labeled tag
Medchemexpress LLC HY-75087 500mg Medchemexpress, (R)-pyrrolidine-2-carboxylic acid CAS:344-25-2 Purity:>98%
Medchemexpress, HY-P7271 10ug NGFR (HEK293-expressed), Human CAS: Recombinant Human NGF Receptor (HEK293-expressed) is a member of tumor necrosis factor receptor superfamily, acts as a marker of cells with tumor-initiating capacity in multiple malignancies, including head and neck squamous cell carcinoma. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Genscript Corporation PDGF R beta/CD140bBiotin Hi
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains The PDGF-AA PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities Where as PDGF R alpha binds all three PDGF isoforms with high affinity PDGF R beta binds PDGF-BB only with high-affinity PDGF R plays an essential role in blood vessel development by promoting proliferation migration and recruitment of pericytes and smooth muscle cells to endothelial cells Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites
American Research Products Inc Rat fibroblast growth factor 2
Rat fibroblast growth factor 23 (FGF23) ELISA Kit from CUSABIO Detection Range 1 56 pg/mL-100 pg/mL Sensitivity 0 39 pg/mL Sample serum plasma cell culture supernates tissue homogenates Method Sandwich