General Cell Lines and Cell Cultures
Eurofins Discoverx PathHunter CHO-K1 RARβ Protein Interaction Cell Line, 2 vials. (93-0326C2)
The PathHunter RARβ Protein Interaction cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting NHR activation and recruitment of cofactors. This cell line enables assessment of ligand (e.g. retinoic acid) based NHR activation via detection of SRCP (steroid receptor co-activator peptide) recruitment. The included cell line overexpresses ProLink-tagged RARβ NHR and EA-tagged steroid receptor co-activator peptide (SRCP). Upon activation of RARβ, induced interaction with SRCP leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/nhr.
STEMCELL Technologies Human Bone Marrow CD34+ Cells, Frozen, Size: 2 x 10^6 cells
Start experiments confidently with ready-to-use, ethically sourced, CD34+ stem and progenitor cells from adult human bone marrow. With personalized service, custom products, flexible delivery times, and the option to reserve entire lots to prescreen cells for applications, we help you get the cells you need. Isolated immunomagnetically using positive selection and cryopreserved in serum-free medium, cells are collected using Institutional Review Board (IRB)-approved consent forms and protocols. Additional documentation to meet institutional requirements and high-resolution HLA typing (Class I and Class II alleles and CMV status) are available upon request. Heparin is added during collection as an anticoagulant. Contact techsupport@stemcell.com for donor specifications (BMI category, smoking status, ethnicity, etc.). Donors are screened for HIV-1, HIV-2, hepatitis B, and hepatitis C. Certain products are only available in select territories.
Biochain Institute Inc Paraffin Tissue Section - Multiple Sclerosis Disease: Brain: Cerebellum, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC Pfizer Pneumococcal polysaccharide powder Type 8 (d8) 10mg
Purified pneumococcal polysaccharide type 8 is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal polysaccharide type 8 can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Discovery Life Sciences NHL FL Active Tx PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Eurofins Discoverx PathHunter CHO-K1 EDG7 β-Arrestin Cell Line, 2 vials. (93-0636C2)
The PathHunter EDG7 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. LPA) based activation of EDG7 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged EDG7 and EA-tagged β-Arrestin-2. Activation of EDG7 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Staphylococcus haemolyticus
Resistant to ampicillin, piperacillin-tazobactam, cefotaxime, cefazolin, and amoxicillin-clavulanate (interpretation of results is based on the product insert for the antibiotic). Resistant to ciprofloxacin, oxacillin, penicillin, clindamycin, erythromycin, ofloxacin, and gentamicin (interpretation of results is based on CLSI). Sensitive to tetracycline and vancomycin (interpretation of results is based on CLSI). Formerly Staphylococcus hominis.
ATCC Eubacterium hallii
Eubacterium hallii strain VPI B4-27 is a whole-genome sequenced bacterial type strain that was isolated from human feces.
Biochain Institute Inc Matched Pair - Paraffin Tissue Section - Human Primary Tumor and Normal (PP): Breast, 5 x2 slides /PK
BioChain's human paraffin tissue section matched pair products include: Primary Pair (PP), Primary and Metastatic Pair (PM). PP consists of paraffin tissue sections of primary tumor and its adjacent normal tissue; PM consists of paraffin tissue sections of primary tumor and corresponding metastatic tumor. Paraffin tissue sections in each pair are prepared from the same donor. This product line is ideal for localization of tumor- specific genes and tumor metastatic genes.
ATCC Quantitative Genomic; RNA from Influenza; A virus (H1N1pdm); strain A/California/07;/2009 NYMC X-179A
Quantitative genomic RNA from Influenza A virus (H1N1pdm) strain A/California/07/2009 NYMC X-179A can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load.
ATCC Saccharomyces cerevisiae; NRRL Y-567
An ampoule containing viable cells suspended in cryoprotectant.
Biochain Institute Inc Paraffin Tissue Section Panel - Mouse Whole Brain Segmentation Panel, 5 slides/PK
Whole brain segmentation panels are designed for study whole brain of small animals. The animals' whole brain was procured intact and was fixed in formaling, then it was sliced into 6 equal coronal regions. Each region is 2 mm thick. The 6 regions were embedded in the same paraffin block. The paraffin section panel cut from this block can enable scientists or research investigators do biochemical analysis, such as the determination of neurotransmitter and metabolite concentrations for reproducible brain regions (i.e. discrete terminal fields or nuclei).
Biochain Institute Inc Frozen Tissue Section - Human Tumor: Esophagus, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx PathHunter U2OS MC4R β-Arrestin Cell Line, 2 vials. (93-0211C3)
The PathHunter MC4R cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. α-MSH) based activation of MC4R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC4R and EA-tagged β-Arrestin-2. Activation of MC4R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.