General Cell Lines and Cell Cultures
Genscript Corporation CHO-K1/G15/CXCR3
Chemokine (C-X-C motif) receptor 3 (CXCR3) belongs to the CXC chemokine receptor family Similar to other chemokine receptors it is a G protein-coupled receptor (GPCR) CXCR3 has two distinct splice variants CXCR3A and CXCR3B demonstrating different binding affinities CXCR3-A binds to the CXC chemokines CXCL9 (MIG) CXCL10 (IP-10) and CXCL11 (ITAC) while CXCR3-B can also bind to CXCL4 in addition to CXCL9 CXCL10 and CXCL11 GenScript s human CXCR3A-expressing stable subline is guaranteed to function properly in calcium flux assay
Genscript Corporation CHO-K1/SST3/G15 Stable Cell L
Recombinant CHO-K1 cells stably overexpress human somatostatin receptor 3 (SST3) on the surface and contain high levels of G protein G i to couple with the receptor in downstream signaling pathways
Genscript Corporation CHO-K1/B7-H3 Stable Cell Line
Recombinant CHO-K1 cells stably overexpress human CD276 (B7-H3) on the surface The surface expression of B7-H3 is validated by FACS analysis This cell line is recommended for cell-based binding assay to screen antibodies against B7-H3 or to measure binding affinity between B7-H3 and anti-B7-H3 antibodies
Cell Biologics MONKEY SKELETAL MUSCLE CELLS
CYNOMOLGUS MONKEY PRIMARY SKELETAL MUSCLE CELLS - Frozen Vial
Amsbio LLC Uterus, endometrium Normal snap-frozen tissue
Uterus endometrium Normal snap-frozen tissue
Genscript Corporation CHO-K1/cyno CD155 Stable Cell
CD155 commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5) is a type I transmembrane single-span glycoprotein and belongs to the nectins and nectin-like (Necl) subfamily CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV) an etiologic agent of the central nervous system disease poliomyelitis The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells CD155 may assist in an efficient humoral immune response generated within the intestinal immune system It s been shown that CD155 can be recognized and bind by DNAM-1 and CD96 which promotes the adhension migration and NK-cell killing Thus inducing cell-mediated tumor-specific immunity
Genscript Corporation CHO-K1/V1B Stable Cell Line
The antidiuretic hormone arginine vasopressin (AVP) receptors are G protein-coupled receptors which consists of at least three types V1A (vascular/hepatic) and V1B (anterior pituitary) receptors which act through phosphatidylinositol hydrolysis to mobilize intracellular Ca sup 2 /sup and V2 (kidney) receptor which is coupled to adenylate cyclase V1B receptors are expressed in anterior pituitary where they mediate the release of ACTH Its peripheral actions such as antidiuresis contraction of vascular smooth muscle and stimulation of hepatic glycogenolysis are well characterized
Genscript Corporation CHO-K1/VPAC2/G15 Stable Cell
Recombinant CHO-K1 cells stably overexpress human vasoactive intestinal peptide receptor 2 (VPAC2) on the surface and contain high levels of G protein G s to couple with the receptor in downstream signaling pathways
Genscript Corporation CHO-K1/CD16B NA1 Stable Cell L
Recombinant CHO-K1 cells stably overexpress human Fc fragment of IgG receptor IIIb (Fc RIIIb/CD16B NA1) The surface expression of CD16B NA1 is validated by FACS analysis This stable cell line product is designed for measuring binding affinity and stability of Fc region of antibodies Fc fusion proteins or antibody based biologics that bind with CD16B during biologics research and development