General Cell Lines and Cell Cultures
ATCC Quantitative Genomic DNA from; Candida parapsilosis; Strain CBS 604
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine fungal load.
ATCC Pseudomonas aeruginosa; Strain PGO2396
Pseudomonas aeruginosa strain PGO2396 is a bacterial strain that was collected from the sputum sample of a cystic fibrosis patient during a Phase III clinical trial that tested the effectiveness of aerosolized Tobi (Tobramycin).
Eurofins Discoverx cAMP Hunter CHO-K1 PROKR1 Gs Cell Line, 2 vials. (95-0090C2)
The cAMP Hunter PROKR1 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prokinectin, EG-VEGF) based activation of PROKR1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type PROKR1, a naturally Gs coupled GPCR. Upon activation of PROKR1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biotium CDX2 (GI Epithelial Marker) (CDX2/2951R), CF594 conjugate, 0.1mg/mL
The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher
Eurofins Discoverx InCELL Hunter HEK 293 RIPK2 Kinase Binding Cell Line, 2 vials. (96-0050C1)
The InCELL Hunter HEK 293 RIPK2 Kinase Binding Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with kinases. This cell line enables assessment of compound-engagement-based stabilization of RIPK2 via detection of RIPK2 levels. This product uses EFC technology. The cell line included overexpresses RIPK2 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is denatured by the heat treatment and no EFC signal is produced. When compound engages and heat-stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Revvity Health Sciences Inc cAMPZen Frozen Human Prostanoid EP2 Cell Line, HEK293 Cells
cAMPZen Frozen Human Prostanoid EP2 Cell Line, HEK293 Cells
ATCC Human Rhinovirus 3; Strain: FEB
Rhinovirus 3 strain FEB is propagated in HeLa cells (ATCC CCL-2). This strain was isolated from the throat washings of a human patient. The product has applications in respiratory disease research.
Revvity Health Sciences Inc Tag-lite Angiotensin AT2 Receptor Frozen & Labeled Cells, 200 Assay Points
Tag-lite Angiotensin AT2 Receptor Frozen & Labeled Cells, 200 Assay Points
ATCC Salmonella enterica; subsp. enterica; serovar Minnesota
Salmonella enterica subsp. enterica serovar Minnesota strain mR595 is a mutant derived from strain S1114. This bacterial culture has applications in emerging infectious disease research and enteric disease research.
Biochain Institute Inc Frozen Tissue Section - Progressive Supranuclear Palsy: Brain: Cerebellum, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Revvity Health Sciences Inc AequoZen Human Muscarinic M1 Cell Line, CHO-K1 Frozen Cells
AequoZen Human Muscarinic M1 Cell Line, CHO-K1 Frozen Cells
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Small Intestine, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx PathHunter Jurkat SIRPa Signaling Cell Line, 2 vials. (93-1135C19)
The PathHunter SIRPa Checkpoint Signaling cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting signaling checkpoints. This cell line enables assessment of ligand (e.g. CD47) based activation of SIRPa receptors via detection of SH2 domain protein recruitment. The included cell line overexpresses ProLink-tagged SIRPa target protein and EA-tagged SH2 domain protein. Upon activation of the receptor by its ligand or an agonist antibody, recruitment of SH2 domain protein to the phosphorylated receptor tail leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/checkpoint.