General Cell Lines and Cell Cultures
Eurofins Discoverx ChemiScreen BB3 Bombesin Receptor Membrane Preparation, 1 vial. (HTS160M)
The ChemiScreen BB3 Bombesin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of BRS3 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
ATCC NCI-H2030; Lung Adenocarcinoma; Human (Homo Sapiens)
NCI-H2030 [H2030] is a cell line exhibiting epithelial morphology that was isolated in 1988 from the lungs of a non-smoking male with non-small cell lung cancer. Use these cells for your lung cancer research.
ATCC Microvascular Endothelial Cell Growth Kit-BBE
Microvascular Endothelial Cell Growth Kit-BBE contains components that when added to Vascular Cell Basal Medium (ATCC PCS-100-030) create a complete cell culture environment for microvascular endothelial cells isolated from normal human tissues.
ATCC NCI-H1650 (H1650); Bronchoalveolar carcinoma; Human (Homo Sapiens)
NCI-H1650 [H-1650, H1650] is a cell line exhibiting epithelial morphology that was isolated in 1987 from the lung tissue of a 27-year-old, male smoker with stage 3B, bronchoalveolar carcinoma. Use these cells for your immuno-oncology and lung cancer research.
ATCC CMT-93; Rectal Carcinoma; Mouse (Mus musculus)
CMT-93 is a cell line exhibiting epithelial morphology that was isolated from the rectum of a mouse with polyploid carcinoma. This cell line was deposited by LM Franks and can be used in cancer research.
ATCC Piezo1 knock-out HEK293T; Embryonic; Kidney; Human (Homo sapiens)
The Piezo1 knock-out HEK293T cell line can be used to assess ion channel activity by electrophysiology without any interference from endogenous mechanically activated currents caused by the ion channel Piezo1.
ATCC NCI-H1688; Lung Carcinoma; Human (Homo sapiens)
NCI-H1688 [H1688] is an epithelial-like cell that was derived from a liver metastasis isolated from the lung of a patient prior to therapy. This cell line can be used in cancer research.
Biolegend MojoSort™ anti-Biotin Nanobeads; Reactivity: Species independent, all species; Apps: Cell Sep - Pos, Cell Sep - Neg; Size: 100 μL
MojoSort™ anti-Biotin Nanobeads; Reactivity: Species independent, all species; Apps: Cell Sep - Pos, Cell Sep - Neg; Size: 100 μL
Eurofins Discoverx cAMP Hunter CHO-K1 rDRD2L (Long Isoform) Gi Cell Line, 2 vials. (95-0130C2)
The cAMP Hunter rDRD2L Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine, pergolide) based activation of rDRD2L GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type rDRD2L, a naturally Gi/Go coupled GPCR. Upon activation of rDRD2L, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx cAMP Hunter CHO-K1 DRD2S (Short Isoform) Gi Cell Line, 2 vials. (95-0084C2)
The cAMP Hunter DRD2S Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD2S GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type DRD2S, a naturally Gi/Go coupled GPCR. Upon activation of DRD2S, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Immunology Consultants anti-Phospho Tau-231 Antibody - Monoclonal (Clone #101)
Clone 101 targets a unique pTau‑231 epitope, providing complementary detection to Clone 100. This monoclonal antibody offers high specificity for phosphorylated Tau with minimal cross‑reactivity, enabling sensitive detection in ELISA, Western blotting, and immunoassay formats. MT231‑80A‑101 is well suited for Alzheimer’s disease biomarker development, Tau phosphorylation pathway research, and studies examining early neurodegenerative mechanisms. Its reproducible performance ensures dependable detection across diverse sample types.
Eurofins Discoverx PathHunter TACR2 Activated GPCR Internalization U2OS Cell Line, 2 vials. (93-0677C3)
The PathHunter TACR2 Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of TACR2 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged TACR2. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting TACR2-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 LXRα Protein Interaction Cell Line, 2 vials. (93-0389C2)
The PathHunter LXRα Protein Interaction cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting NHR activation and recruitment of cofactors. This cell line enables assessment of ligand (e.g. oxysterols) based NHR activation via detection of SRCP (steroid receptor co-activator peptide) recruitment. The included cell line overexpresses ProLink-tagged LXRα NHR and EA-tagged steroid receptor co-activator peptide (SRCP). Upon activation of LXRα, induced interaction with SRCP leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/nhr.
Eurofins Discoverx PathHunter CHO-K1 GPR78 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0370C2A)
The PathHunter GPR78 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR78 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR78 and EA-tagged β-Arrestin-2. Activation of GPR78 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 GPR23 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0336C2A)
The PathHunter GPR23 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. LPAs) based activation of GPR23 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR23 and EA-tagged β-Arrestin-2. Activation of GPR23 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.