Sera
Innovative Research Inc Pld Hmn Srm Off Clot Fml/ Ml
Pooled Human Serum Off The Clot Female and Male Mix - Pooled Human Serum from Innovative Research is whole blood derived. The whole blood is collected from donors in an FDA-approved collection center. The blood is allowed to clot and is then processed into serum via centrifugation, and is frozen immediately after processing.
Innovative Research Inc Sngl Dnr Hmn Crohn Disease Srm
Single Donor Human Crohn's Disease Serum - Single Donor Human Crohn's Disease Serum from Innovative Research is whole blood derived. Available volumes are variable, and range from 0.5ml to 1.0ml per vial (you can select your exact samples from our inventory, if desired). A detailed patient history and clinical information is recorded at the time of draw, and multiple samples and plasma/serum matched sets from the same donor are often available. Innovative Research has a wide network of collection centers, which allows us to collect from nearly any donor type. We are able to deliver to you a list of available samples that includes comprehensive donor data so that you can select the particular samples that best fit with your research requirements.
Cayman Chemical 3-DeazaurIdIn 50mg
A nucleoside analog; converted intracellularly to 3-deazauridine triphosphate, which inhibits the biosynthesis of CTP; inhibits the growth of L1210 leukemia cells when used at a concentration of 6 µM; dose-dependently reduces mortality in a mouse model of leukemia; enhances the incorporation of decitabine into DNA in leukemia cells when used at a concentration of 20 µM; reduces mortality when used at a dose of 100 or 150 mg/kg and combined with decitabine in a mouse model of leukemia
Cayman Chemical PropIonylLcarnItInchLRI 50mg
A carnitine derivative; increases the basal release of PGE2 and 6-keto prostaglandin F1α in carrageenan-stimulated isolated rat peritoneal cells contaminated with neutrophils; increases the basal release of thromboxane B2 in non-neutrophil-contaminated carrageenan-stimulated isolated rat peritoneal cells; reduces the production of ROS and decreases NOX2, NOX4, and ICAM-1 expression in HUVECs; increases the rate of revascularization and the hind limb vascular area in a rabbit model of hind limb ischemia at 10 mg per animal
Cayman Chemical Latnoprost Lacton DIol 50mg
Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Latanoprost lactone diol is an intermediate in the synthesis of latanoprost. Latanoprost lactone diol can be converted to the free acid of latanoprost by reduction with DIBAL followed by Wittig reaction with commercially available reagents.
Cayman Chemical 5 6 7-TrImethoxyflavon 50mg
A flavonoid with diverse biological activities; reduces the viability of HepG2 and Hep3B carcinoma cells at 50 µM; decreases HSV-1 and poliovirus replication in HSV-1- or poliovirus-infected Vero cells, as well as decreases CMV replication in CMV-infected MRC-5 cells (IC50s = 3.2, 32, and 8 mg/L, respectively); inhibits LPS-induced NO, PGE2, Tnf-α, Il-1β, and Il-6 production in RAW 264.7 macrophages at 20 or 40 µM; increases survival in a mouse model of LPS-induced sepsis at 40 mg/kg
Cayman Chemical LIthospermosIde 100mg
A nitrile glucoside with antitumor activity; inhibits TPA-induced activation of EBV-EA in Raji cells
Cayman Chemical Nethyl PRfluoroctnsulfon 100mg
A perfluoroalkyl substance; decreases maternal body weight and food intake in pregnant rats and induces abortions and decreases fetal weight in pregnant rabbits at 10 mg/kg; has been found in landfill leachate and the atmosphere
Cayman Chemical OsIlodrostat 50mg
An aldosterone synthase inhibitor; selective for human aldosterone synthase over rat aldosterone synthase (IC50 = 160 nM); inhibits increases in plasma aldosterone levels induced by angiotensin II or ACTH in rats (ED50s = 0.6 and 1.1 mg/kg, respectively); reduces mean arterial pressure and prolongs survival in rats expressing human renin and angiotensinogen, a double-transgenic model of angiotensin II-dependent hypertension, in a dose-dependent manner
Cayman Chemical 7-ChlorokynurenIc AcId 50mg
A glycine-site selective NMDA receptor antagonist; selectively binds to the NMDA receptor glycine-binding site (IC50 = 0.56 µM) over the NMDA-, quisqualate-, and kainate-binding sites (IC50s = 169, 153, and >1,000 µM, respectively); induces antidepressant-like activity in a variety of behavioral tests in mice at 0.1 and 1 mg/kg
Cayman Chemical NDesethylamIodaronhydroch 50mg
the major CYP3A4 metabolite of amiodarone; used as an analytical reference standard for monitoring clinical efficacy of amiodarone in plasma samples
Cayman Chemical ArachIdnyl CyclopropylaMD 50mg
A potent and selective CB1 receptor agonist (Kis = 2.2 and 715 nM for CB1 and CB2, respectively); induces hypothermia in mice with the same efficacy as AEA in spite of its much higher affinity for the CB1 receptor and thus is a possible substrate for FAAH
Cayman Chemical BretylIumtosylate 100mg
A class III antiarrhythmic agent; has antiadrenergic activity in isolated tissue preparations; an inhibitor of the Na+/K+-ATPase (IC50 = 4.5 mM); prevents ventricular fibrillation in anesthetized dogs in a model of sudden coronary death at 10 mg/kg; inhibits NCTs, as well as increases action potential delay and the absolute refractory period in isolated mouse vas deferens sympathetic nerve terminals
Cayman Chemical ArachIdonIc AcId 100mg
Keystone essential fatty acid that is converted by COX, LO, and epoxygenase enzymes into more than 150 potent metabolites in species ranging from fungi to plants to mammals
Cayman Chemical PIoglItazon 50mg
A PPARγ agonist (EC50 = ~500-600 nM for both human and murine PPARγ); selective for PPARγ over PPARα exhibiting low level activation of PPARα at 1 µM and 5.4-fold activation at a concentration of 10 µM; reduces hyperglycemia, hyperlipidemia, and hyperinsulinemia in a dose-dependent manner in male Wistar fatty rats from 0.3-3 mg/kg; reduces the number of lesions in a TRAP model; decreases production of neuroinflammatory cytokines and reduces immobility in the forced swim and tail suspension tests in a mouse model of chronic mild stress at 2.5 mg/kg