Human Sera
Cayman Chemical Coprostnol 100mg
A cholesterol derivative; formed via conversion of cholesterol to cholestenone then coprostanone intermediates or by direct reduction of the 5,6 double bond; commonly used as a marker of sewage contamination in soil and watersheds
Cayman Chemical Hexaconazole 100mg
A triazole fungicide; inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol; curative against powdery mildew on barley plants at 6.7 mg/L; improves water, proline, and protein contents as well as increases non-enzymatic and enzymatic antioxidant and apigenin-7-glucoside content in M. chamomilla plants during a water deficit stress tolerance test at 15 mg/L; inhibits the differentiation of mouse embryonic stem cells into cardiomyocytes (EC50 = 16.6 μM); induces bone morphological defects in mouse fetuses
Cayman Chemical AcetylLcarnItInd3chLRI 50mg
An internal standard for the quantification of L-acetylcarnitine by GC- or LC-MS
Cayman Chemical GlutamInase-IN-3 50mg
An inhibitor of GAC (IC50 = 0.24 µM); inhibits the proliferation of PC3 and LNCaP prostate cancer cells (IC50s = 6.14 and 2.13 µM, respectively) and non-cancerous CCD-1072Sk fibroblasts (IC50 = 15.39 µM)
Cayman Chemical HederagenIn 100mg
A triterpene saponin with diverse biological activities; increases production of ROS, reduces colony formation, and induces apoptosis in cisplatin-resistant HNC cells; suppresses tumor growth in a cisplatin-resistant HNC mouse xenograft model at 50, 100, and 200 mg/kg; reduces aortic atherosclerotic lesion area, serum cholesterol and LDL levels, and iNOS protein levels in a rat model of atherosclerosis; reduces ethanol-induced production of TNF-α, IL-6, and COX-2, ALDH2 mRNA expression, and liver damage in a rat model of alcohol-induced hepatotoxicity at 50 mg/kg; induces autophagy and inhibits oligomerization of α-synuclein in a mouse model of MPTP-induced Parkinson's disease
Cayman Chemical 5 6 7-TrImethoxyflavon 100mg
A flavonoid with diverse biological activities; reduces the viability of HepG2 and Hep3B carcinoma cells at 50 µM; decreases HSV-1 and poliovirus replication in HSV-1- or poliovirus-infected Vero cells, as well as decreases CMV replication in CMV-infected MRC-5 cells (IC50s = 3.2, 32, and 8 mg/L, respectively); inhibits LPS-induced NO, PGE2, Tnf-α, Il-1β, and Il-6 production in RAW 264.7 macrophages at 20 or 40 µM; increases survival in a mouse model of LPS-induced sepsis at 40 mg/kg
Cayman Chemical -OxypeucednIn hydrate 50mg
A furanocoumarin; active against a variety of bacteria and fungi (MICs = 9.76-625 UG/ml); inhibits proliferation of human MK-1 gastric and HeLa cervical cancer cells, as well as murine B16/F10 melanoma cells (EC50s = 47.2, 80.3, and 42 UG/ml, respectively); also inhibits proliferation of sensitive and multidrug-resistant L5178Y murine lymphoma cells (IC50s = 41.96 and 60.58 µM, respectively)
Cayman Chemical Eprosartnmesylate 50mg
A competitive AT1 receptor antagonist (IC50s 1.4 – 3.9 nM and an elimination half-life of 5 to 7 hours) that blocks angiotensin II receptors on both sympathetic nerve terminals and blood vessels
Cayman Chemical FormontIn 100mg
An isoflavonoid phytoestrogenic compound found in soy-based foods; acts as an agonist of the aryl hydrocarbon receptor (EC50 = 0.13 µM) and has been reported to possess antitumor and antiviral activity
Cayman Chemical FIdaxomycIn 50mg
A natural macrocyclic antibiotic that inhibits RNA polymerase with selectivity for Gram-positive bacteria over Gram-negative bacteria (IC50s = 0.4 and 6 μM, respectively); has potent antibacterial activity against most Gram-positive bacteria and effectively targets the Gram-positive C. difficile (MIC = 12 ng/ml)
Cayman Chemical namInhydrochlorIde 50mg
A natural degradation product of neomycin; a common core molecule used in the synthesis of aminoglycoside antibiotics
Cayman Chemical DolutegravIr 50mg
A potent inhibitor of HIV integrase (IC50 = 2.7 nM for HIV-1 integrase-catalyzed strand transfer in vitro); inhibits HIV-1 viral replication (EC50 = 0.51 nM) in PMBCs; CC50 values are 189 and 52 µM in unstimulated and stimulated PBMCs; prevents replication of several HIV-1 strains (EC50s = 0.36-2.1 nM) that are resistant to NRTIs, NNRTIs, and protease inhibitors and impairs their ability to infect CIP4 cells
Cayman Chemical ChlorIdoN NdIsalIcylIden 100mg
An inducer of ferroptosis; induces ferroptosis, but not apoptosis or necroptosis, in NB1 cancer cells at 3 µM; inhibits proliferation of BJAB, NALM-6, Jurkat, MelHO, and MCF-7 cancer cells (IC50s = 0.07, 2.5, 1.5, 3 and 5 µM), as well as daunorubicine- and vincristine-resistant NALM-6 cells at 0.04-0.125 µM
Cayman Chemical TrIamcInolon 100mg
A synthetic glucocorticoid; increases expression of the calcitonin receptor in in murine osteoclast-like cells at 1 μM; reduces heat hyperalgesia and mechano-allodynia and decreases the number of TNF-α-positive mast cells in injured sciatic nerve in a rat model of chronic constriction injury-induced neuropathic pain at 3 mg/kg, s.c.; reduces levels of the glycosaminoglycans hyaluronic acid and chondroitin-4-sulfate in human keloid implants in athymic nude mice
Sigma Aldrich Fine Chemicals Biosciences Human Serum Heat Inactivated (from male AB clotted whole blood), USA origin, sterile-filtered, MFCD00165829
Human Serum Heat Inactivated (from male AB clotted whole blood), USA origin, sterile-filtered
