Human Sera
Cayman Chemical N2Isobutyryl5O 4 4dIme 100mg
A building block; has been used in the synthesis of oligodeoxyribonucleotides
Cayman Chemical AtrasentnhydrochlorIde 50mg
An ETA antagonist (Ki = 69 pM for the human receptor); selective for ETA over ETB (Ki = 139 nM for the human receptor) and a panel of 29 other receptors at 10 µM; inhibits endothelin-1-induced secretion of arachidonic acid from HPSMCs (pA2 = 10.5), as well as endothelin-1-induced vasoconstriction in isolated rat aortic rings (pA2 = 9.2); inhibits endothelin-1-induced increases in the pressor response in normotensive rats at 10 mg/kg; reduces urinary levels of albumin, TGF-β, and a PGE2 metabolite, as well as decreases the number of macrophages, in a rat model of streptozotocin-induced diabetic nephropathy at 5 mg/kg per day
Innovative Research Inc Pooled Human Serum Off The Clot 100ml
Pooled Human Serum from Innovative Research is whole blood derived. The whole blood is collected from donors in an FDA-approved collection center. The blood is allowed to clot and is then processed into serum via centrifugation, and is frozen immediately after processing.Â
Innovative Research Inc Single Donor Human Breast Cancer Serum
Single Donor Human Breast Cancer Serum from Innovative Research is whole blood derived. Available volumes are variable, and range from 0.5ml to 1.0ml per vial (you can select your exact samples from our inventory, if desired). A detailed patient history and clinical information is recorded at the time of draw, and multiple samples and plasma/serum matched sets from the same donor are often available.
Innovative Research Inc Single Donor Human Rheumatoid Arthritis Serum
Single Donor Human Rheumatoid Arthritis Serum from Innovative Research is whole blood derived. Available volumes are variable, and range from 0.5ml to 1.0ml per vial (you can select your exact samples from our inventory, if desired). A detailed patient history and clinical information is recorded at the time of draw, and multiple samples and plasma/serum matched sets from the same donor are often available.
Cayman Chemical KalIdIn380-389humnpo 50mg
An endogenous kinin peptide agonist of bradykinin B2 and B1 receptors; binds to bradykinin B2 (IC50 = 0.63 nM) and B1 receptors (Ki = 3.23 nM); levels in interstitial muscle are increased in women with work-related trapezius myalgia
Cayman Chemical SophocarpIn 100mg
An alkaloid with diverse biological activities; cytotoxic to various cancer cell lines (IC50s = 1.64-12.86 mM); nematocidal against B. xylophilus in vitro; reduces infarct size, cardiac muscle fiber swelling and hypertrophy, and neutrophil infiltration in a rat model of myocardial ischemia and reperfusion injury at 30 mg/kg; decreases liver weight, fibrosis, and levels of IL-6, TNF-α, and TGF-β1 in a rat model of NASH; reduces carrageenan-induced hind paw edema in rats and decreases acetic acid-induced writhing in mice at 15 and 30 mg/kg
Cayman Chemical 17phenl trInor ProstglndI 50mg
An F-series prostaglandin and an FP receptor agonist; induces calcium mobilization in 3T3-L1 fibroblasts expressing the human receptors (EC50 = 2.2 µM); ocular administration reduces IOP in normotensive dogs and ocular hypertensive monkeys at 0.03% w/v
Cayman Chemical PRfluorobutylsulfonamID 100mg
A perfluoroalkyl substance; has been found as a contaminant in wastewater and consumable Tampa Bay oysters
Cayman Chemical PyraclostrobIn 100mg
A carbamate fungicide; active against a variety of fungi (IC50s = 0.18, 0.005, 0.36, 0.03, and 0.15 UG/ml, respectively); is toxic to zebrafish (LC50 = 42.17 UG/L); induces nuclear and mitochondrial deformities in the heart and brain, as well as decreases heart rate, blood volume ejected, and cardiac output, in zebrafish larvae at 37.5 UG/L; decreases locomotor activity and body weight, as well as induces hypothermia and diarrhea, in mice at 400 mg/kg
Cayman Chemical PyraclostrobIn 50mg
A carbamate fungicide; active against a variety of fungi (IC50s = 0.18, 0.005, 0.36, 0.03, and 0.15 UG/ml, respectively); is toxic to zebrafish (LC50 = 42.17 UG/L); induces nuclear and mitochondrial deformities in the heart and brain, as well as decreases heart rate, blood volume ejected, and cardiac output, in zebrafish larvae at 37.5 UG/L; decreases locomotor activity and body weight, as well as induces hypothermia and diarrhea, in mice at 400 mg/kg
Cayman Chemical PXS-5505hydrochlorIde 50mg
A pan inhibitor of LOX and LOXL1-4 (IC50s = 0.493, 0.159, 0.57, 0.18, and 0.19 µM for fibroblast LOX and recombinant human LOXL1-4, respectively); selective for LOX and LOXL1-4 over DAO, VAP-1, MAO-A, and MAO-B (IC50s = >30 µM for all); reduces bleomycin-induced increases in dermal thickness and the levels of α-smooth muscle actin in a mouse model of systemic sclerosis at 15 mg/kg; reduces collagen crosslinking in KPC CAF 3D organotypic matrices; increases survival to a greater extent than gemcitabine alone when administered in combination with gemcitabine, reduces gemcitabine-induced increases in collagen levels and stiffness, and reduces liver metastatic burden in autochthonous KPC pancreatic ductal adenocarcinoma mouse models at 20 mg/kg
Cayman Chemical 5 7 3 4 5Pentamethoxyflav 50mg
A flavonoid with diverse biological activities; inhibits pancreatic lipase in a cell-free assay; reduces lipid accumulation in 3T3-L1 adipocytes; inhibits transactivation of Nrf2 in a reporter assay using HEK293T cells at 10, 25, or 50 µM; sensitizes cisplatin-resistant A549 NSCLC cells to cisplatin; inhibits LPS-induced NO production in RAW 264.7 macrophages and GES-1 cells; decreases blood glucose levels and renal fibrosis in a rat model of STZ-induced diabetes at 5 mg/kg
Cayman Chemical PImavnserIn 50mg
A 5-HT2A inverse agonist (IC50 = 1.86 nM; Ki = 0.5 nM); selective for 5-HT2A over a panel of 65 ion channels, enzymes, and receptors (Kis = >100 nM); reduces DOI-induced head-twitch behavior and prepulse inhibition deficits in rats at doses of 3 mg/kg, p.o. and 1-10 mg/kg, s.c., respectively; exhibits antipsychotic-like activity, reducing (+)-MK-801-induced hyperactivity in mice; acts synergistically with haloperidol or risperidone to suppress (+)-MK-801-induced hyperactivity and attenuates haloperidol- and risperidone-induced catalepsy in rats
Cayman Chemical nohesperIdIn 100mg
A flavonoid with diverse biological activities; inhibits osteoclast differentiation, bone resorption, activation of NF-κB and NFAT by RANKL, and calcium oscillations in vitro; in vivo administration protects ovariectomized mice from bone loss; reduces lipid accumulation in HepG2 cells and reverses hyperlipidemia in a mouse model of diet-induced obesity; increases glucose tolerance and decreases insulin resistance while simultaneously decreasing serum triglycerides and total cholesterol and inhibiting lipid accumulation in livers in a mouse model of diabetes