Human Sera
Cayman Chemical BHC 50mg
A selective allosteric orally bioavailable pan-Akt inhibitor (IC50s 5.0 4.5 and 16 nM for Akt1 Akt2 and Akt3 respectively)
Cayman Chemical SucLeuLeuValTyrAMCtrIf 100mg
A sesquiterpene lactone with anticancer activity inhibits the proliferation of MDA-MB-231 MDA-MB-468 and MCF-7 human breast cancer cells (IC50s 5.211 3.405 and 9.083 UM respectively after 48 hours) inhibits migration of MDA-MB-231 cells at 2.5 5 and 10 UM reduces tumor volume in an MDA-MB-231 orthotopic mouse xenograft model at 25 and 50 mg/kg
Cayman Chemical Fluprostenol Lacton DIol 100mg
A G protein-biased peptide agonist of GLP-1R selectively induces cAMP accumulation in HEK293 cells expressing human GLP-1R overBarrestin recruitment in CHO-K1 cells expressing human GLP-1R (EC50s 0.63 and 79 nM respectively) induces insulin secretion in INS-1 832/3 cells (EC50 6.3 nM) reduces food intake and body weight increases plasma insulin levels and decreases plasma glucose HbA1c glucagon and triglyceride levels in diabetic db/db mice from 1.5-6 nmol/kg
Cayman Chemical Pteryxn 50mg
A peptide agonist of CaSR selective for CaSR over a panel of 33 receptors and ion channels as well as the norepinephrine transporter at 10 UM increases intracellular calcium levels in HEK293T cells expressing the human CaSR receptor (EC50 0 53 UM) inhibits parathyroid secretion from primary rat parathyroid cells (EC50 0 36 UM in the presence of calcium) decreases parathyroid hormone and calcium in plasma and serum respectively in a model of chronic renal insufficiency with secondary hyperthyroidism in nephrectomized rats fed high-phosphorus diet at 0 3 1 and 3 mg/kg
Bio IVT HUMAN A/B SERUM 100ML MIN=2
Human AB serum derived from apharesis plasma. Steile filtered, mycoplasma and endotoxin tested
Cayman Chemical BHC 100mg
An HIV maturation inhibitor (IC90 6.4 nM) active against a variety of HIV isolates
Cayman Chemical GluLeu 100mg
An analytical reference standard that is structurally similar to known phytocannabinoids intended for research and forensic applications
Cayman Chemical CItrulInated Hsp70R357 Po 1ea
Immunogen Diglycine-modified histone peptide Host Mouse Species Reactivity Species independent Cross Reactivity ( ) Diglycyl-modified lysine (-) Unmodified lysine Applications IP and WB
Cayman Chemical Ocmene 50mg
A cell-permeable benzoxazolo-sulfonamide compound that blocks human FBPase-1 enzymatic activity by competing at the AMP allosteric binding site (IC50 3 4 UM Ki 1 1 UM) blocks glucose production in starved rat hepatoma cells (IC50 6 6 UM)
Cayman Chemical Fluprostenol Lacton DIol 50mg
A building block has been used in the synthesis of drUG-linker molecules for ADCs
Cayman Chemical Lndane 100mg
A DNA alkylating agent active metabolite of dacarbazine (DTIC) active degradation product of temozolomide cytotoxic to L-cells and decreases thymidine and uridine uptake by 55 and 65 respectively at 1 mM cytotoxic to TLX5 murine lymphoma cells induces formation of mammary adenofibromas in rats when administered at a cumulative dose of 890 mg per animal over 14 weeks
Cayman Chemical Elemene 100mg
The primary PGD2 metabolite formed from PGD2 via PGFS in the liver or lung induces contraction of isolated cat iris sphincter (EC50 0 045 UM) induces contraction of isolated human bronchial smooth muscle from 0 1-30 UM induces ERK and CREB phosphorylation as well as increases the viability of MCF-7 breast cancer cells stably expressing the FP receptor at 0 1 and 1 UM