Human Sera
Cayman Chemical Eprosartnmesylate 50mg
A competitive AT1 receptor antagonist (IC50s 1.4 – 3.9 nM and an elimination half-life of 5 to 7 hours) that blocks angiotensin II receptors on both sympathetic nerve terminals and blood vessels
Cayman Chemical AgomelatIn 100mg
A melatonin receptor agonist (Kis = 0.14 and 0.41 nM for MT1 and MT2, respectively) and 5-HT2B and 5-HT2C antagonist (Kis = 0.26 and 0.71 nM, respectively); inhibits the 5-HT2-mediated penile erection response in rats at 40 mg/kg; increases extracellular levels of noradrenaline and dopamine in the frontal cortex of freely moving rats at 20-80 mg/kg; reduces immobility time in the forced swim test and increases the amount of time spent in the open arms of the elevated plus maze in mice in a transgenic neuroendocrine model of depression at 10 mg/kg
Cayman Chemical Hexaflumuron 100mg
A chitin synthesis inhibitor that is used to bait and eliminate termite colonies; also effective against the raisin moth, cowpea weevil, and Asiatic rice borer
Cayman Chemical AlexIdInhydrochlorIde 50mg
An alkyl bis(biguanide) antiseptic which kills plaque forming microorganisms; binds to LPS and LTA and inhibits fungal phospholipase B (IC50 ~ 250 nM); inhibits the mitochondrial phosphatase PTPMT1 (IC50 = 1.08 μM, in vitro) and induces apoptosis in cancer cell lines (ED50 = 1.8-2.6 μM)
Cayman Chemical ML-7hydrochlorIde 50mg
Inhibits smooth MLCK (Ki = 0.3 µM) 10-fold more potently than its parent compound ML-9
Cayman Chemical 1S 3S3Hydroxycyclopentn 50mg
A synthetic intermediate useful for pharmaceutical synthesis.
Innovative Research Inc Single Donor Human Alzheimer's Serum
Single Donor Human Alzheimer's Serum from Innovative Research is whole blood derived. Available volumes are variable, and range from 0.5ml to 1.0ml per vial (you can select your exact samples from our inventory, if desired). A detailed patient history and clinical information is recorded at the time of draw, and multiple samples and plasma/serum matched sets from the same donor are often available.
Cayman Chemical Maltotetraose 100mg
A tetrasaccharide; increases the α-amylase synthesis rate in B. stearothermophilus three-fold greater than sucrose or glucose when used at at 0.1 mM; inhibits the growth of E. carotovora in a cylinder-agar plate assay at 750 μg/ml; inhibits TNF-α-induced expression of ICAM-1 in MOVAS-1 mouse VSMCs
Cayman Chemical ALP Stop SolutIon 15mL
ALP Stop Solution has been tested and formulated to work exclusively with Cayman’s Alkaline Phosphatase Colorimetric Activity Assay Kit (Item No. 701710).
Cayman Chemical SInapaldehyde 50mg
A phenylpropanoid with diverse biological activities; an inhibitor of FTase (IC50 = 23.99 µM); inhibits TNF-α-induced NF-κB transcriptional activity in a reporter assay using HepG2 cells (IC50 = 13.25 µM); reduces LPS-induced NO production in RAW 264.7 cells (IC50 = 5.92 µM); scavenges DPPH and ABTS radicals in cell-free assays (IC50s = 83.02 and 43.15 µM, respectively); active against Gram-positive and Gram-negative bacteria (MICs = 64-128 UG/ml); inhibits α-glucosidase (IC50 = 98.81 µM)
Cayman Chemical UDPaDGalactosesodIM sal 50mg
A nucleotide sugar; an agonist of the purinergic P2Y14 receptor (EC50 = 0.67 µM); red blood cell levels are decreased in patients with PKU and maple syrup urine disease
Cayman Chemical BenzetImIdehydrochlorIde 50mg
A muscarinic acetylcholine receptor antagonist; induces mydriasis and inhibits pilocarpine-induced salivation and lacrimation in rats (ED50s = 0.06 and 0.04 mg/kg, respectively)
Cayman Chemical DrondaronhydrochlorIde 100mg
An antiarrhythmic agent; inhibits muscarinic acetylcholine receptor-dependent potassium currents induced by carbachol or intracellular loading of GTPγS in single cells isolated from guinea pig atria (IC50s = 0.1 and 1 µM, respectively); reduces sinus frequency and prolongs APD in isolated rabbit ventricular myocardium at 50 and 100 mg/kg; increases atrial APD and the AERP in a dog model of atrial fibrillation
Cayman Chemical 3mthylaPyrroldInobutIoph 50mg
An isomer of 4-methyl-α-PBP, having the methyl group attached at the 3 position of the phenyl ring, instead of the 4 position; intended for forensic and research applications