Primary Antibody Matched Pairs
CD96 Monoclonal Antibody (3.3), Functional Grade, In Vivo PLATINUM™, Leinco Technologies™
Rat Monoclonal Antibody
ABclonal Technology SRPK1 Rabbit mAb
This gene encodes a serine arginine protein kinase specific for the SR (serine arginine-rich domain) family of splicing factors The protein localizes to the nucleus and the cytoplasm It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors Alternative splicing of this gene results in multiple transcript variants Additional alternatively spliced transcript variants have been described for this gene but their full length nature have not been determined
Sino Biological Recombinant Human PAR2 Protein (VLP, Full-Length, His & FLAG Tag)
A DNA sequence encoding the Human F2RL1-VLP (Full Length) (P55085) (Ile26-Tyr397) was expressed, with a Flag tag at the N-terminus, a polyhistidine tag and a strep tag at the C-terminus.
Sino Biological Recombinant Human IL-12 R beta 1/IL12RB1 Protein (ECD, hFc Tag)
A DNA sequence encoding the Human IL12RB1 (NP_005526.1) (Met1-Glu540) was expressed with the Fc region of human IgG1 at the C-terminus.
Sino Biological Recombinant Human CCR8 Protein (Nanodisc, Flag-Strep & His tag)
A DNA sequence encoding the Human CCR8 (P51685)(Met1-Cys228) & (Asn230-Ser318) was expressed and linked by a Fusion Protein, with a Flag tag followed by a Strep Tag at the N-terminus, a polyhistidine tag at the C-terminus. Within the expressed regions, there are several proprietary thermostabilizing mutations.This protein was prepared using our Nanodisc platform. Nanodisc is a versatile tool for studying membrane proteins. Using styrene-maleic acid (SMA) copolymer, membrane proteins can be extracted directly from prokaryotic and eukaryotic expression systems in the absence of detergents to preserve the protein structure and function better. Compared to membrane scaffold proteins (MSPs) nanodiscs, SMA nanodiscs also have the advantage of preserving proteins' nature by maintaining native lipids surrounded without introducing any heterologous proteins, which allows studies of protein structure and functions in a native-like environment.
Cayman Chemical WB 4101hydrochlorIde 50mg
An α-AR antagonist; inhibits norepinephrine-induced contraction in isolated rat vas deferens (pA2 = 9.8); inhibits carbamoylcholine-induced contractions in isolated guinea pig taenia caeci (pA2 = 8.9)
Sino Biological Recombinant Human APRIL/TNFSF13 Protein (AVI & His Tag), Avi-tag Biotinylated, MALS-verified
A DNA sequence encoding the Human TNFSF13 (O75888-1) (Gln111-Leu250) was expressed with an N-terminal AVI tagged polyhistidine tag. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed. This construct has a trimer design.
Sino Biological Recombinant Human Claudin-4/CLDN4 Protein (Detergent, Full-length, Flag Tag)
A DNA sequence encoding the Human CLDN4-Detergent (Full Length) (O14493) (Met1-Val209) was fused with a flag tag at the C-terminus. Within the expressed regions, there are several proprietary thermostabilizing mutations.This protein was prepared using our detergent platform. The transmembrane proteins' hydrophobic regions pose a challenge in maintaining their native conformation post-extraction from cellular membranes in standard buffers. To address this, our detergent technology platform utilizes a traditional yet proven membrane protein extraction method, incorporating detergents to stabilize the proteins. This method efficiently produces highly purified membrane protein products, suitable for use in early drug screening and research applications.