Bovine Secondary Antibodies
Cayman Chemical ANTIBODY LSN3318839 500ug
A positive allosteric modulator of GLP-1R; potentiates increases in cAMP accumulation induced by GLP-1 (9-36) in INS-1 832/3 cells; increases insulin levels in the presence, but not absence, of GLP-1 (9-36) in INS-1 832/3 cells under high-glucose conditions at 1 and 3 µM; reduces blood glucose levels in GIPR knockout mice in an oral glucose tolerance test at 30 mg/kg; has an additive effect on reducing blood glucose levels in GIPR knockout mice at 10 or 30 mg/kg in combination with sitagliptin
Cayman Chemical ANTIBODY MSD-M1PAM 500ug
A positive allosteric modulator of M1 mAChRs; enhances ACh-induced calcium production in a calcium mobilization assay from 0.1-10 µM; reverses scopolamine-induced deficits in freezing behavior in mice from 1-30 mg/kg; attenuates deficits in self-ordered spatial search in cynomolgus macaques and in the object retrieval detour task in rhesus macaques
Genscript Corporation CK-MB 8D8HC
Creatine kinase (CK) is a dimeric enzyme including three isoforms of creatine kinase BB MM and MB Level of serum CK-MB will be increased within 4-6 hours after a myocardial infarction (MI) CK-MB is considered as a useful marker for the diagnosis of myocardial infarction
Cayman Chemical GInsenosIde CK 5mg
A metabolite of ginsenoside Rb1; formed from ginsenoside Rb1 via intestinal bacterial exo-β-D-glucosidase; reduces protein levels of MMP-2 and pro-MMP-9, and inhibits growth, adhesion, and invasion of, MHCC97-H HCCs at 50 and 75 µM; inhibits metastasis in an MHCC97-H mouse xenograft model; reduces the percentage of memory B cells in the spleen, the number of swollen joints, and lymph node hyperplasia in an adjuvant-induced model of rheumatoid arthritis; reduces the accumulation of Aβ42 in the rat hippocampal CA1 and CA3 regions in a rat model of vascular dementia; also increases the percentage of time spent in the target quadrant of the Morris water maze at 100 and 200 mg/kg in a rat model of vascular dementia
Cayman Chemical ANTIBODY TDI-11861 500ug
A soluble adenylyl cyclase inhibitor (IC50 = 3.3 nM); selective for sAC over AC1, AC2, AC5, AC8, and AC9 at 100 nM, a panel of 322 kinases (IC50s = >1,000 nM for all), and 46 other targets, including GPCRs, nuclear receptors, and ion channels (RC50s = >9 µM for all); inhibits capacitation-induced cAMP accumulation in isolated mouse and human sperm at 5 µM; reduces sodium bicarbonate-induced increases in mouse and human sperm beat frequency at 5 µM; induces temporary infertility in male mice without affecting mating behavior after a single dose of 50 mg/kg
Cayman Chemical AdenIn15N5hydroCLOrID h 500ug
An internal standard for the quantification of adenine by GC- or LC-MS