Goat Secondary Antibodies
Cayman Chemical KEMPFPKYPVEP Peptide (bovine, ovine) (trifluoroacetate salt), Purity: ≥95%, 100 mg
A peptide fragment of β-casein; can be produced by the protease M from A. oryzae and is found in dairy products fermented by fungi but not bacteria; increases the levels of dopamine, norepinephrine, and homovanillic acid, but not serotonin, in the frontal cortex of mice at 2 mg/kg; improves spatial alternation retention in the Y-maze spatial alternation task and increases novel object exploration time in a novel object recognition test in a mouse model of scopolamine-induced amnesia at 2 mg/kg
Cayman Chemical 1,2-Dioleoyl-3-trimethylammoniumpropane (methyl sulfate), Purity: ≥98%, CAS: 144189-73-1, 50 mg
A cationic lipid; has been used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells; has been used in the composition of small unilamellar liposomes formulated as gene delivery vectors for gene therapy
Cayman Chemical 4-Methoxycinnamic Acid, Purity: ≥98%, CAS: 830-09-1, 50 g
A phenolic acid with diverse biological activities; reduces A. fumigatus biofilm formation from 0.4-3.2 mM; reduces the number of dysplastic aberrant crypt foci and dysplastic liver cells in a rat model of 1,2-dimethylhydrazine-induced colon carcinogenesis at 80 mg/kg; reverses MK-801-induced decreases in the preference ratio for the novel object in the novel object recognition test in mice; reduces plasma glucose concentrations in a rat model of STZ-induced diabetes
Cayman Chemical SLC3A2CD98 Heavy ChaIn RabbI
A σ1 receptor agonist inhibits reductions in mitochondrial oxygen consumption and lipid peroxidation induced by AB (25-35) in isolated mouse hippocampus at 1 mg/kg improves deficits in novel object recognition induced by AB (25-35) in mice as well as reduces tau phosphorylation and AB (1-42) levels in the hippocampus in the same model at 1 mg/kg increases the latency to fall in the rotarod test reduces gait impairments and reduces increases in the mean acoustic startle response in an Mecp2-/- mouse model of Rett syndrome at 30 mg/kg per day
Cayman Chemical Vanillic Acid, Purity: ≥98%, CAS: 121-34-6, 50 g
A phenol with diverse biological activities; inhibits biofilm formation by CREH (MIC = 0.8 mg/ml); inhibits doxorubicin-induced cell death in H9c2 rat cardiomyocytes at 12 µg/ml; reduces cardiac levels of lactate dehydrogenase, cardiac troponin-1, and MDA in a rat model of doxorubicin-induced cardiotoxicity at 10, 20, and 40 mg/kg; reduces hyperglycemia and renal levels of TBARS, TNF-α, and NF-κB, as well as attenuates impaired renal function in a rat model of STZ- and nicotinamide-induced diabetes; reduces BALF inflammatory cell infiltration and airway inflammation in a rat model of ovalbumin-induced asthma at 25 and 50 mg/kg
Cayman Chemical Adenosine-5'-O-diphosphoribose phosphate (sodium salt), Purity: ≥98%, 3.2 mg
An HMG-CoA reductase inhibitor; selectively inhibits rat liver microsomal HMG-CoA reductase in its non-allosteric form with apparent Ki values of 53 and 550 µM at high and low thiol concentrations, respectively, which are associated with its non-allosteric and allosteric forms
Cayman Chemical Cytidine 5'-methylenediphosphate (sodium salt), Purity: ≥95%, 2 mg
An inhibitor of ecto-5’-nucleotidase (Ki = 898 nM)
Cayman Chemical 2,3-Indolobetulin, Purity: ≥95%, CAS: 2365493-59-8, 100 mg
A derivative of betulin; has been used in the synthesis of α-glucosidase inhibitors
Cayman Chemical Betamethasone 21-phosphate (sodium salt hydrate), Purity: ≥95%, 250 mg
A synthetic glucocorticoid; prevents increases in macrophage and eosinophil numbers in BALF and decreases blood leukocyte numbers in a guinea pig model of parainfluenza-3 viral infection at 8 mg/kg; inhibits cell infiltration into the aqueous humor in a rat model of endotoxin-induced uveitis when administered topically or subcutaneously at doses of 0.01-1% or 1 mg/kg, respectively; increases maximal lung pressure volume curves in fetal sheep when administered to pregnant ewes at 0.75 gestation at doses of 80 and 170 µg/kg; increases body weight, impairs learning and memory, increases anxiolytic behavior, and reduces hippocampal neurogenesis in CD-1 mice but reduces body weight and increases neurogenesis with no effect on anxiety in high-anxiety DBA/2 mice when administered at a dose of approximately 25 mg/kg per day in the drinking water for seven weeks
Cayman Chemical 1-(2,3-Dichlorophenyl)urea, Purity: ≥95%, CAS: 13142-51-3, 250 mg
A building block; has been used in the synthesis of compounds with cytokinin-like activity
Cayman Chemical Scopolamine, Purity: ≥98%, CAS: 51-34-3, 500 mg
An alkaloid with diverse biological activities; an antagonist of mAChRs (Kis = 0.19, 1.41, and 0.18 nM for the rat M1, M2, and M3 receptors, respectively); reduces acetylcholine-induced contractions in isolated guinea pig ileum (IC50 = 8.1 nM); inhibits oxotremorine-induced tremors in mice (ED50 = 0.23 mg/kg); increases fine motor activity counts and ambulatory activity in rats in a home-cage activity test (ED50 = 0.12 mg/kg for both); has been used to induce learning deficiencies or amnesia in animal models
Cayman Chemical RabbItntIStagIgGDyLIght1ea
Rabbit anti-S tag IgG conjugated to DyLight 550 Antibody: Anti-S-tag (KETAAAKFERQHMDS) IgG Isotype: IgG Dye: DyLight 550 Excitation max. λ: 562 nm Emission max. λ: 576 nm Uses: Fluorescence-activated cell sorting, flow cytometry, and microscopy
Cayman Chemical L-Azidohomoalanine (hydrochloride), Purity: ≥95%, CAS: 942518-29-8, 250 mg
A clickable form of L-homoalanine; has been used for semiquantitative analysis of newly synthesized proteins in A549 epithelial cancer cells and neural progenitor cells derived from patients with fragile X syndrome
Cayman Chemical 2-Chloroadenosine-5'-O-diphosphate (sodium salt), Purity: ≥95%, CAS: 82927-78-4, 2.3 mg
A derivative of ADP; induces aggregation of, and inhibits PGE2-induced production of cAMP in, isolated human platelet-rich plasma; induces relaxation of precontracted isolated guinea pig taenia coli strips (pD2 = 6.74); decreases arterial blood pressure in rats; inhibits the ATPase activity of mortalin (apparent Ki = 45.05 µM for the human enzyme)