Goat Secondary Antibodies
Immunoreagents Inc GOAT A-HUMAN IGG/A/M AP
Secondary Antibody; Goat anti-human IgG + IgA + IgM - Affinity Pure, Host: Goat, Format: Liq, Label: None , Applications: WB, ELISA, IHC/ICC, IF, IP, FC
Immunoreagents Inc GOAT A-RAT IGG AP
Secondary Antibody; Goat anti-rat IgG (H&L) - Affinity Pure, Host: Goat, Format: Liq, Label: None, Applications: WB, ELISA, IHC/ICC, IF, IP, FC
Cayman Chemical Nicergoline, Purity: ≥98%, CAS: 27848-84-6, 500 mg
An α1-AR antagonist; binds to α1-ARs in rat brain membranes (Ki = 12.5 nM); inhibits α1-AR agonist-induced contractions in endothelium-denuded isolated rat aortic rings and perfused mesenteric vascular beds (pA2s = 8.6 and 11.1, respectively); inhibits cirazoline-induced pressor responses in rats at 0.5 µg/kg per minute, i.v.; improves postischemic glutamate uptake and reduces neuronal cell death and mortality in a rat model of global brain ischemia induced by mild hyperthermia at 32 mg/kg; increases corneal NGF levels and accelerates corneal wound healing in a rat model of ocular injury
Cayman Chemical Amylmetacresol, Purity: ≥98%, CAS: 1300-94-3, 5 g
A topical antiseptic and analgesic agent; inhibits depolarization-induced whole-cell sodium currents in HEK293 cells expressing human Na
Cayman Chemical 5-Aminothalidomide, Purity: ≥95%, CAS: 191732-76-0, 1 g
A derivative of (±)-thalidomide; inhibits the proliferation of EA.hy926 endothelial cells (IC50 = 200 µM); an intermediate in the synthesis of a PROTAC c-MET degrader with antiproliferative activity in c-MET-sensitive cancer cells; an intermediate in the synthesis of a thalidomide derivative that reduces clinical scores in a mouse model of EAE
Immunoreagents Inc GOAT A-MOUSE IGG AP
Secondary Antibody; Goat anti-mouse IgG (H&L) - Affinity Pure, min x w/Bo, Gt, Hu, Rb or Rt IgG, Host: Goat, Format: Liq, Label: None, Applications: WB, ELISA, IHC/ICC, IF, IP, FC
Cayman Chemical Tetradecylphosphocholine, Purity: ≥95%, CAS: 77733-28-9, 1 g
A zwitterionic surfactant; has been used in the solubilization and purification of GPCRs; has been used as the stationary phase in ion chromatography for the determination of inorganic acids; CMC = ~0.12 mM
Cayman Chemical Chlormezanone, Purity: ≥98%, CAS: 80-77-3, 500 mg
A muscle relaxant; induces paralysis in mice, guinea pigs, dogs, cats, and monkeys (EC50s = 133, <200, 100-250, 50, and 50 mg/kg, respectively); increases ataxia induced by pentobarbital and alcohol in mice; blocks the crossed extensor reflex of the spine without affecting the knee-jerk reflex in cats; induces head drop in rabbits
Cayman Chemical 1-Myristoyl-2-hydroxy-sn-glycero-3-PG (sodium salt), Purity: ≥95% (9:1 mixture of 1-acyl and 2-acyl), CAS: 326495-21-0, 1 g
A lysophospholipid; has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems
Cayman Chemical Norfloxacin, Purity: ≥98%, CAS: 70458-96-7, 25 g
A fluoroquinolone antibiotic; inhibits the growth of Gram-positive and Gram-negative bacteria (MICs = 4 and 1 μg/ml for S. aureus and P. aeruginosa, respectively); inhibits the growth S. pseudintermedius, S. aureus, E. coli, Pasturella, and S. canis isolates from dogs (mean MIC50s = 0.25, 1, 0.03, 1, and 1 μg/ml, respectively); topical administration reduces corneal ulcer size in a rabbit model of P. aeruginosa corneal infection at 0.1 % v/v; prevents encrusted cystitis in bladder and increases survival in a rat model of Corynebacterium group D2 infection at 80 mg/kg/day
Cayman Chemical Methylene Blue (hydrate), Purity: ≥95%, CAS: 122965-43-9, 250 g
A cationic dye with diverse biological activities; inhibits the catalytic function of inducible and constitutive nitric oxide synthases; inhibits MAO and increases the activity of mitochondrial cytochrome C oxidase; stabilizes systemic circulation without increasing peripheral resistance, decreases lipid peroxidation, and reduces anoxic tissue injury in brain and heart in a porcine model of global ischemia and reperfusion injury; inhibits MAO activity in brain and reduces the age-related decline in grip strength and spatial memory in old mice at 250 μM in drinking water; reduces immobility time in the forced swim test in mice at 15,30, and 60 mg/kg; commonly used to stain cells and tissues in research
Cayman Chemical (–)-Sitagliptin Carbamoyl Glucuronide, Purity: ≥90%, CAS: 940002-59-5, 1 mg
A minor phase II metabolite of (–)-sitagliptin; formed by N-carbamoyl glucuronidation; has been found in rat and dog plasma
Cayman Chemical W-Conotoxin MVIIC trifluoroa
An N-, P-, and Q-type calcium channel blocker; blocks N-type calcium channels on rat SCGs and P-type calcium channels on rat Purkinje neurons (Kds = 30 and ~50 nM, respectively, in the presence of 5 mM barium); blocks Q-type channels in rat CA3 neurons; completely blocks calcium uptake by rat brain synaptosomes (2.5 μM in the presence of 5 mM potassium); blocks potassium-evoked dopamine release from rat striatal slices (IC50 = ~128 nM) and potassium-evoked calcium-dependent glutamate release from rat brain synaptosomes
Cayman Chemical 1-O-Hexadecyl-sn-glycerol, Purity: ≥95%, CAS: 506-03-6, 500 mg
An alkyl glyceryl ether; reduces UVB-induced cell death and production of ROS and PGE2 in NHEKs; increases coronary flow and left ventricular developed pressure and reduces MDA formation ex vivo in a rat heart model of ischemia/reperfusion injury
Cayman Chemical n-Nonyl-β-D-glucopyranoside, Purity: ≥95%, CAS: 69984-73-2, 500 mg
An anionic chiral surfactant; commonly used for the solubilization and crystallization of biological membrane proteins; has been used in the separation of drug enantiomers by micellar electrokinetic chromatography