Goat Secondary Antibodies
Cayman Chemical IsoxsuprInhydrochlorIde 10g
An adrenergic receptor modulator; induces vasodilation of NE-precontracted isolated equine common digital artery strips, an α-AR effect, and induces relaxation of isolated fowl cecum, an effect that can be blocked by the β-AR antagonist propranolol; has antinociceptive effects in an acetic acid writhing test in mice; inhibits oxytocin-induced contractions in isolated rat uterus (IC50 = 9.15 µM); delays labor onset in rats by 31.63 hours at 10 mg/kg on days 13-21 of gestation but increases heart rate with increasing concentration
Cayman Chemical Sp-2'-Deoxy-2'-fluoroadenosine-5'-O-(1-thiotriphosphate) (sodium salt), Purity: ≥95%, 2.6 mg
An isomer of 2'-F-dATP-a-S
Cayman Chemical 2- 6-Aminohexylthioadenosine
An aminohexylthiol-substituted derivative of ATP; has been used in the synthesis of biotinylated derivatives of ATP
Cayman Chemical Acenaphthene-d10, Purity: ≥99% deuterated forms (d1-d10), CAS: 15067-26-2, 1 g
An internal standard for the quantification of acenaphthene by GC- or LC-MS
Cayman Chemical Rp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) (sodium salt), Purity: ≥95%, CAS: 80902-29-0, 2.6 mg
A sulfur-containing derivative of dGTP
Cayman Chemical 1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin, Purity: ≥90%, CAS: 19408-74-3, 1 mg
A polychlorinated dibenzodioxin; induces the formation of liver adenomas or carcinomas in rats at 2.5 µg/kg once per week in combination with 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin; has been found in the air near municipal waste incinerators and in blood from individuals that lived near or in herbicide-sprayed regions
Cayman Chemical Isoconazole (nitrate), Purity: ≥98%, CAS: 24168-96-5, 10 g
An imidazole with antimicrobial activity; active against clinical isolates of Candida species with MIC values ranging from 0.12 to 2 μg/ml; active against T. mentagrophytes and T. rubrum at 0.1 µg/ml and the bacteria C. tuberculostearicum, methicillin-resistant S. aureus (MRSA), and S. epidermis (MICs = 3.9, 32, and 5.6 mg/L, respectively); induces ROS production in S. aureus; inhibits HO-1 and HO-2 in rat spleen and rat brain microsomes, respectively (IC50s = 5.6 and 32.6 µM, respectively)
Cayman Chemical BIBF 1120 (esylate), Purity: ≥98%, CAS: 656247-18-6, 500 mg
A VEGFR, FGFR, and PDGFR inhibitor (IC50s = 13-34, 37-610, 59, and 65 nM for VEGFR1-3, FGFR1-4, PDGFRα, and PDGFRβ, respectively); selective for VEGFR, FGFR, and PDGFR over a panel of 33 kinases but does inhibit FLT3, LCK, LYN, and Src (IC50s = 16-156 nM); inhibits growth factor-dependent proliferation of HUVECs, HSMECs, HUASMCs, and BRPs (EC50s = 7-290 nM); reduces tumor microvessel density and the number of PDGFRβ-expressing perivascular cells in a FaDu head and neck small cell carcinoma mouse xenograft model at 100 mg/kg; inhibits tumor growth in a Caki-1 renal cancer mouse xenograft model
Cayman Chemical Isoconazole (nitrate), Purity: ≥98%, CAS: 24168-96-5, 25 g
An imidazole with antimicrobial activity; active against clinical isolates of Candida species with MIC values ranging from 0.12 to 2 μg/ml; active against T. mentagrophytes and T. rubrum at 0.1 µg/ml and the bacteria C. tuberculostearicum, methicillin-resistant S. aureus (MRSA), and S. epidermis (MICs = 3.9, 32, and 5.6 mg/L, respectively); induces ROS production in S. aureus; inhibits HO-1 and HO-2 in rat spleen and rat brain microsomes, respectively (IC50s = 5.6 and 32.6 µM, respectively)
Cayman Chemical Teneligliptin (hydrobromide hydrate), Purity: ≥98%, CAS: 1572583-29-9, 250 mg
A DPP-4 inhibitor (IC50s = 0.37 and 0.29 nM for the human and rat enzymes, respectively); selective for DPP-4 over DPP-8 and DPP-9 (IC50s = 260 and 540 nM, respectively, for the human enzymes); inhibits increases in plasma glucose levels in an oral glucose tolerance test in Zucker fatty rats at 0.03-1 mg/kg; reduces body weight, inhibits hepatic steatosis, and decreases plasma insulin levels in a mouse model of high-fat diet-induced obesity at 30 and 60 mg/kg; scavenges hydroxyl radicals in a cell-free assay (IC50 = 0.315 mM); decreases urinary levels of 8-OHdG in a DPP-4-deficient rat model of STZ-induced diabetes at 10 mg/kg per day
Cayman Chemical Phenazopyridine (hydrochloride), Purity: ≥98%, CAS: 136-40-3, 5 g
An azo dye with analgesic properties; decreases the bladder distension-induced firing rate of afferent bladder Aγ-fibers, but not C-fibers, in anesthetized rats at 0.3, 1, and 3 mg/kg
Cayman Chemical Propylparaben, Purity: ≥98%, CAS: 94-13-3, 5 g
A paraben with diverse biological activities; active against several strains of P. stutzeri (MICs = 250-300 µg/ml); binds to estrogen receptors in a concentration-dependent manner; decreases sperm counts and serum testosterone levels in rats at 1% in the diet; has been found in influent and effluent wastewater
Cayman Chemical PAMAM Dendrimer G5.0 Succinamic Acid (water solution), 500 mg
A succinamic acid-terminated PAMAM dendrimer; ~59 Å in diameter; has 128 surface groups; inhibits plaque formation induced by MERS-CoV in Vero cells at 10 µM; active against S. aureus; PAMAM G5.0-SAH encapsulating doxorubicin decreases cell viability in KB carcinoma cells; does not induce mortality in zebrafish at 250 ppm in tank water
