Goat Secondary Antibodies
ABclonal Technology STAT3 Rabbit pAb
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. This gene also plays a role in regulating host response to viral and bacterial infections. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome.
Jackson Immuno Research Labs 4nm Colloidal Gold-AffiniPure Goat Anti-Human Serum IgA α Chain Specific (LM Grade)
4nm Colloidal Gold-AffiniPure Goat Anti-Human Serum IgA α Chain Specific (LM Grade)
Jackson Immuno Research Labs Alexa Fluor 594-AffiniPure Fab Fragment Goat Anti-Human IgM Fc5µ Fragment Specific
Alexa Fluor 594-AffiniPure Fab Fragment Goat Anti-Human IgM Fc5µ Fragment Specific
Jackson Immuno Research Labs Alexa Fluor 594-AffiniPure F(ab')2 Fragment Goat Anti-Human IgG Fcγ Fragment Specific (min X Bov Ms Rb Sr Prot)
Alexa Fluor 594-AffiniPure F(ab')2 Fragment Goat Anti-Human IgG Fcγ Fragment Specific (min X Bov Ms Rb Sr Prot)
Jackson Immuno Research Labs Rhodamine Red-X-AffiniPure Goat Anti-Human Serum IgA α Chain Specific
Rhodamine Red-X-AffiniPure Goat Anti-Human Serum IgA α Chain Specific
Cayman Chemical DIcyclomInhydrochlorIde 1g
A M1 and M2 muscarinic acetylcholine receptor antagonist (Kis = 3.16 and 44.7 nM, respectively); inhibits carbachol-stimulated inositol phosphate accumulation in guinea pig cortex (Ki = 12 nM; pA2 = 7.88); inhibits potassium-induced contraction of ileum, colon, and duodenum in anesthetized rats by 21.85, 30.81, and 37.86%, respectively (10 mg/kg, i.v.)
Cayman Chemical PefloxacInmesylate hydrate 10g
A broad-spectrum and synthetic fluoroquinolone antibiotic; active against clinical isolates of E. coli, K. pneumoniae, S. aureus, and G. vaginalis (MIC90s = 0.12, 0.5, 0.5, and 32 mg/L, respectively) selectively inhibits E. coli topoisomerase I and DNA gyrase over calf thymus topoisomerase I (IC50s = 45, 4.5, and >140 μg/ml, respectively) in cell-free assays; active against systemic E. coli, K. pneumoniae, and P. aeruginosa infections in mice (P50s = 6.5, 29.2, and 219 mg/kg, respectively)
Cayman Chemical 6-ThIogunosIn 1g
A thiopurine nucleoside; preincubation decreases uridine and methionine incorporation into ribosomal RNA in Novikoff-Hepatoma cells at 10 and 100 µM, respectively; inhibits the germination of B. anthracis spores (Ki = 98 µM) and prevents spore-induced cytotoxicity in RAW 264.7 macrophages in a concentration-dependent manner; is active against E. coli (IC50 = 2 µM); reduces the proliferation of MOLT-4 leukemia cells (IC50 = 0.19 µM)
Cayman Chemical Ethyl OrselInate 1g
A lichen metabolite and a derivative of lecanoric acid; inhibits the proliferation of human Hep-2 larynx carcinoma, MCF-7 breast cancer, and 786-0 kidney carcinoma cells, as well as B16-F10 murine melanoma and non-cancerous Vero cells (IC50s = 31.2, 70.3, 47.5, 64.8, and 28.1 UG/ml, respectively); toxic to brine shrimp (LC50 = 495 µM)
Immunology Consultants Affinity Purified Goat anti-Human IgM Antibody, 1.0 mg
Goats were immunized with highly purified human IgM and the resulting antiserum was collected. Antibody was solid phase adsorbed and immunoaffinity purified off a human IgM containing immunosorbent. Antibody concentration was determined using an absorbance at 280 nm: 1.4 equals 1.0 mg of IgG. This antibody reacts with human IgM as determined by IEP and ELISA techniques. It is suitable for blotting, ELISA and IHC applications. This antibody may cross react with IgM from other species. Optimal working dilutions should be determined experimentally by the investigator.
Cayman Chemical D-PenIcIlamIn 10g
A chelating agent; increases urinary and fecal copper excretion and decreases liver copper concentration in a rat model of copper overload when administered at 0.67 mmol/kg per day; dissolves copper-rich granules in hepatic lysosomes of LEC rats (100 mg/kg per day); has anticonvulsant and proconvulsant effects in mice when administered at 0.5 and 250 mg/kg, respectively, which are blocked by the NOS inhibitors L-NAME and 7-nitroindazole