Cayman Chemical MPC-6827hydrochlorIde 10mg
An inhibitor of tubulin polymerization with anticancer activity; inhibits tubulin polymerization in a cell-free assay at 0.5, 5, and 50 µM, as well as in A549 cells at 10 nM; induces apoptosis in T47D, HCT116, and SNU-398 cancer cells (EC50s = 2, 3, and 2 nM, respectively); reduces tumor growth in various mouse xenograft models from 2.5-10 mg/kg