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Bioassays, kits, and reagents used to analyze various properties of living cell samples. Products include apoptosis assays, signal transduction assays, and cell growth and differentiation assays.
Homogeneous, colorimetric cell viability assay; requires mixing of MTS and PMS components prior to assay, then a 1- to 4-hour incubation. Standalone MTS powder for applications where optimization of assay for specific cell types or conditions is desired.
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Colorimetric assay for the determination of cell membrane integrity based on detection of LDH release, an indicator of cytotoxicity. Sample transfer steps are required.
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A fast homogeneous, fluorometric method for estimating the number of non-viable cells present in multiwell plates. Based on detection of LDH release, an indicator of cytotoxicity.
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The CytoTox-Fluor Cytotoxicity Assay is a single-reagent-addition, homogeneous, fluorescent assay that measures the relative number of dead cells in cell populations.
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The Kinase-Glo™ Luminescent Kinase Assays are homogeneous non-radioactive systems for determining the activity of purified kinases by quantifying the amount of ATP remaining in solution following a kinase reaction.
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Recombinant human PASK (981-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PASK or PAS domain containing serine/threonine kinase regulates the function of many intracellular signaling pathways involved in stress.
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Recombinant human EIF2AK2 (252-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EIF2AK2 (also known as double-stranded RNA-activated protein kinase) is shown to be involved in HIV/gp120-associated neurodegeneration.
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ACK is a tyrosine kinase that binds CDC42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of CDC42Hs.
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Recombinant full-length human GSK3 alpha was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. GSK3 alpha is a multifunctional protein serine kinase implicated in the control of several regulatory proteins.
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